1.Assessment of left ventricular systolic synchronicity with omnidirectional M-mode echocardiography in dilated cardiomyopathy patients
Chinese Journal of Medical Imaging Technology 2009;25(10):1803-1805
Objective To assess left ventricular radial systolic synchronicity with omnidirectional M-mode echocardiography (OME). Methods OME examination was performed in 21 patients with dilated cardiomyopathy (DCM) and 27 healthy controls. The time to peak radial systolic movement were measured and adjusted by R-R interval. The standard deviation (Tc-SD)and the maximal temporal difference (Tc-dif) of the time to peak radial systolic movement of left ventricular short-axis segments at basal and mid-levels, the septal-to-posterior wall motion delay (SPWMD), septal-to-anterior wall motion delay (SAWMD), septal-to-laterior wall motion delay (SLWMD), septal-to-inferior wall motion delay (SIWMD) and anterior-to-inferior wall motion delay (AIWMD) were used as indicators of systolic dyssynchrony.Results Compared with the controls, Tc-dif, Tc-SD, SLWMD, SPWMD and SIWMD in basal level were significantly higher in the DCM group (P<0.05), while Tc-dif, Tc-SD, SAWMD, SPWMD, SIWMD and AIWMD in mid-level were significantly higher in the DCM group (P<0.05).Conclusion Omnidirectional M-mode echocardiography is useful to evaluate the radial systolic synchrony of the left ventricular in patients with dilated cardiomyopathy.
2.Spinal Sequence Automatic Stitching Based on Biorthogonal Wavelet Transform and Feature Matching
Xue MENG ; Zhensheng DENG ; Xin GUO
Chinese Journal of Medical Physics 2010;27(2):1726-1730
Objective: An automatic seamless stitching method with spinal X-ray image sequence is presented in this paper. Methods: First, biorthogonal wavelet transform is used to implement decomposing of the multi-resolution and the effective edge of the image can be extracted by this method combined with Canny operator. The feature points of the image can be obtained by calculating the edge contour matrix E and the value matrix H. Second, the roughly matching of feature points can be achieved by using Normalized Cross Correlation (NCC) algorithm and the random sample consensus (RANSAC) algorithm is introduced to remove false matching pairs and to achieve precisely matching. Third, the image sequence is automatically sorted with the improved genetic algorithm to achieve automatic stitching. At last, the weighted average fusion algorithm is appfied to achieve smooth and seamless image stitching. This algorithm is robust for the weak-contrast X-ray image sequence. Results: Experimental results show that high-quality and fast image sequence stitching can be obtained automatically by using this method. Conclusions: To a certain extent, it overcomes the shortcomings of X-ray image sequence such as the strong image noise, concentration of values ofpixels, blurred boundaries, large overlap area and the sequence constraint, and therefore it may be applied to in medical imaging field widely.
3.Evaluation of left ventricular radial myocardial motion velocity gradient in assessment of regional myocardial function by omni-directional M-mode echocardiography
Wei GUO ; Bin CHEN ; Zhensheng YE
Chinese Journal of Ultrasonography 2010;19(7):565-568
Objective To assess regional myocardial function by left ventricular radial myocardial motion velocity gradient(MVG) measured by omni-directional M-mode echocardiography(OME). Methods There were 32 patients with hypertrophic cardiomyopathy(HCM), 20 patients with hypertension of left ventricular hypertrophy(HLVH),and 36 healthy volunteers in the study, LEJ-2 mode OME was used to measure and calculate MVG of 16 segment on left ventricular short axes. Results In the control group,MVG on left ventricular short axes were found to be decreased progressively from base plane to apical plane. Compared with the control group,the left ventricular MVG were reduced in HCM group and HLVH group( P <0. 05). Conclusions The left ventricular MVG can correspond directly to regional thickened myocardial motion,and can be used to evaluate left ventricular myocardial function in patients with thickened myocardium.
4.Development of Protective Mask with Dual Canisters & Big Eyes Window for Liquid Propellant
Zhuozhen HAN ; Jixin CONG ; Zhensheng GUO
Chinese Medical Equipment Journal 1989;0(01):-
Objective To develop MFT-2S protective mask with dual canisters and big-eye-window and to improve the three-grade system of protective equipment,so as to solve the problems on protective mask in environment with gas of high concentration.Methods MFT-2S protective mask was derived from MFT-2,with the advantages of MFT-2.The fixation intensity was effectively guaranteed by installing two sets of joint components and stainless steel clamps in the lower part of mask bilaterally.The sealing component was installed in communication component.Each canister was fixed at one side respectively.The fogproof lenses were reinstalled and the length of canister was increased properly.Results The results showed that,compared with MFT-1 mask,the inspiration resistance of MFT-2S mask decreased by a half,its total weight became about 50% of MFT-1 mask,and the leakage coefficient of MFT-2S mask was 0.005 percent.Its antidim character was improved and MFT-2S mask had better protective performance than MFT-2 by twice.Conclusion According to the transformed protection indices,MFT-2S mask,with the advantages of being light,simplified and standardized,can take the place of MFT-1 mask.
5.Experimental study of the change of early regional myocardial function with diabetic using omni-directional Mmode echocardiography
Wei GUO ; Zhensheng YE ; Ying DAI ; Bin CHEN
Chinese Journal of Ultrasonography 2011;20(10):883-886
ObjectiveTo evaluate the role of detecting early change of left ventricular regional myocardial function in the rabbit with type Ⅰ diabetes using omni-directional M-mode echocardiography (OME).MethodsEighty New Zealand rabbits were selected in this study..40 health rabbits were included in the control group,the other 40 with type Ⅰ diabetes were included in the experiment group.The OME was used to measure the peak time of myocardial motion during systole (Ts) and diastole (Td),myocardial velocity gradient during systole (MVGs) and diastole (MVGd) on the left ventricular short axis.These parameters were measured during the first,second,fourth,sixth and eighth week.ResultsOME was able to detect significant changes of Td during the second week,Ts and MVGd during the fourth week,and MVGs during sixth week after modeling ( P <0.05 ).ConclusionsOME is an important method to detect early changes of regional myocardial function in the patients with diabetes.
6.Levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 in serum of cerebral infarction patients with the different classification of TOAST
Lili GAO ; Ruiyou GUO ; Yongchun TANG ; Zhensheng ZHAO
Chinese Journal of Postgraduates of Medicine 2008;31(10):29-31
Objective To determine and compare the levels of serum matrix metalloproteinase (MMP)-2 and MMP-9 in acute stage of cerebral infarction and the relationship and prognosis between them and the classification of TOAST. Methods The levels of MMP-2 and MMP-9 were detected by ELISA in 60 cerebral infarction patients(CI group)while 30 healthy donors were served as control group (NC group).Results The level of MMP-2 in CI group was significantly lower than that in NC group (P<0.01) and the level of MMP-9 was significantly higher than that in NC group (P<0.01).Compared with lacunar infarction (LI) group,the level of MMP-9 was significantly higher in cardiogenic cerebral embolism group(CCE group) and large artery arteriosclerosis cerebral infarction group (LAA group);The serum level of MMP-9 was related to NIHSS.The serum level of MMP-9 in good prognosis patients was significantly lower than that in poor prognosis patients (P<0.01).Conclusions The serum level of MMP-9 is increased after cerebral infarction.The serum level of MMP-9 in the CCE group and LAA group is significantly higher than that in LI group.The level of MMP-9 is a reliable parameter in evaluating the disabilities in cerebral infarction.The level of serum MMP-9 within 24 hours of onset can predict the prognosis of cerebral infarction independently.
7.Diagnostic value of echocardiography for cardiac tumors of 87 cases
Chun WANG ; Wei GUO ; Ying DAI ; Mi OU ; Zhensheng YE
Chinese Journal of cardiovascular Rehabilitation Medicine 2014;23(5):566-568
Objective:To explore the diagnostic value of color Doppler echocardiography for cardiac tumors .Meth-ods:Clinical data of 87 patients with cardiac tumors were retrospectively analyzed ,including their diseased loca-tion ,clinical manif′estations and echocardiography feature .Results:All cardiac tumors obtain pathologic confirma-tion .There were 73 patients (83.9% ) with benign cardiac tumors ,including 66 patients (90.4% ) with myxoma and seven patients with other types ;there were 14 patients (16.1% ) with malignant cardiac tumors .Echocardiography indicated that myxoma was often located in left atrium (n=58) ,most cases possessed pedicell,its activity was large ;Other type benign cardiac tumors feature :The 6 case (86% ) were generated inside cardiac muscle without pedicell, its echo was more strong ;malignant tumors:its attachment surface was wide without pedicell,and it may show with globular or cauliflower ,and accompanied hydropericardium mostly .Conclusion:Echocardiography can dynamically observe the form ,size ,echo and hemodynamic changes of tumors ,its diagnostic accuracy is high .Myxoma is most frequent cardiac tumor .
8.Consistency of omnidirectional M-mode echocardiography and two-dimensional strain in assessment of left ventricular systolic asynchrony
Zhensheng YE ; Wei GUO ; Shunqiong CHEN ; Ying DAI ; Shi YAN ; Min XIE
Chinese Journal of Medical Imaging Technology 2010;26(3):496-499
Objective To investigate the consistency of omnidirectional M-mode echocardiography and two-dimensional strain in assessment of left ventricular (LV) radial systolic asynchrony. Methods Thirty patients with heart failure (HF) and 28 healthy volunteers underwent omnidirectional M-mode echocardiography and two-dimensional strain at the same time. The time to peak radial systolic movement (T_m) of LV in 12 segments were measured with omnidirectional M-mode echocardiography and its standard deviation (T_m-12-sd), and the maximum difference (T_m-12-dif) were calculated. The time to peak radial systolic strain (T_(SR)) of LV in 12 segments were measured with two-dimensional strain and its standard deviation (T_(SR)-12-sd), and the maximum difference (T_(SR)-12-dif) were calculated. The T_m-12-sd, T_m-12-dif, T_(SR)-12-sd and T_(SR)-12-dif were used as systolic asynchrony indicators. The value (-x)±2s in the control group was defined as the normal upper limit which represents 97.7% of the control group distribution. Any values above this limit in HF patients were classified as LV asynchrony. The results of two methods were analyzed with Kappa test. Results Compared with the controls, T_m-12-sd, T_m-12-dif, T_(SR)-12-sd and T_(SR)-12-dif were significantly higher in the HF group (P<0.001); there was consistency between T_m-12-sd and T_(SR)-12-sd, T_m-12-dif and T_(SR)-12-dif in detecting LV systolic asynchrony in HF group (Kappa=0.661, 0.733). Conclusion T_m-12-sd and T_m-12-dif of omnidirectional M-mode echocardiography have consistency with T_(SR)-12-sd and T_(SR)-12-dif of two-dimensional strain. These two technologies both have ability to evaluate LV radial systolic synchronicity.
9.The study of relationship between intelligence impairment and interictal epileptiform discharges spreading in mesial temporal lobe epilepsy.
Zhensheng LI ; Quwen GAO ; Wei WANG ; Jian LIN ; Kairun PENG ; Xiaofei GUO ; Lihui XIA ; Zijuan QI
Chinese Journal of Nervous and Mental Diseases 2018;44(1):6-10
Objective To investigate the relationship between intelligence impairment and interictal epileptiform discharges spreading in mesial temporal lobe epilepsy(mTLE)patients. Method We assessed 145 patients diagnosed as mTLE and their general materials, analyzed the relationship between intelligence impairment and interictal epileptiform discharges spreading. Results ①Patients with mTLE with longer disease course and higher frequencies of epilepsy tended to have a severe impairment in the total intelligence quotient (IQ), verbal intelligence quotient (vIQ) and performance intelligence quotient (pIQ). ② IQ of was negatively correlated with the condition that interictal epileptiform discharges spreading to the ipsilateral central and parietal region in patients with left lesion; pIQ was negatively correlated with the condition that interictal epileptiform discharges spreading to the ipsilateral frontal region, while positively correlated with the condition that interictal epileptiform discharges spreading to the ipsilateral occipital region in patients with right lesion. Conclusion ①Intelligence impairment of mTLE patients is related with courses and frequencies.②Total IQ is more severely impaired by interictal epileptiform discharges spreading to the ipsilateral central and parietal region in left mTLE patients, and the pIQ is more severely impaired by interictal epileptiform discharges spreading to the ipsilateral frontal region in right mTLE patients.