1.The Significance of the Memorial Hall Construction for the Donator of Cadaver
Qingzhong HU ; Zeen WANG ; Zhenshan PENG
Chinese Medical Ethics 2016;29(4):633-634,638
Based on the analysis of the current situation of memorial hall construction for the donator of cada-ver, this paper discussed the significance of memorial hall construction:respecting the donor′s personal dignity, in-carnating humanistic care to the donators′relatives, guiding and promoting the cadaver donation, and becoming the medical ethics education base for medical students.
2.Analysis of drug resistance of Klebsiella pneumoniae lower respiratory tract infection in patients with coexisting pulmonary tuberculosis and diabetes
Peng GAO ; Zhenshan LEI ; Jinbin WU
International Journal of Laboratory Medicine 2016;(3):359-361
Objective To investigate the drug resistance characteristics of Klebsiella pneumoniae lower respiratory tract infection in the patients with coexisting pulmonary tuberculosis (TB) and diabetes mellitus (DM ) to provide a basis for the prevention and treatment of Klebsiella pneumoniae infections .Methods The lower respiratory tract specimens were collected from the patients with coexisting pulmonary TB and DM in the Shenzhen Hospital of Peking University from January 2009 to May 2015 .The bacteri‐al species was identified by using the France Bio‐Merieux Vitek2‐Compact automatic microorganism identification instrument ,the drug susceptibility tests adopted the disk method (K‐B) ,and extended spectrum β lactamase (ESBLs) detection was conducted ,the drug susceptibility test results were judged according to the CLSI standards .The data were analyzed by the WHONET 5 .6 and SPSS18 .0 software .Results 139 strains of Klebsiella pneumoniae were isolated from the lower respiratory tract specimens in the patients with coexisting pulmonary TB and DM ,the ESBLs producing rate was up to 46 .0% .The drug susceptibility testing results showed that the resistance of non‐ESBLs producing and ESBLs producing Klebsiella pneumoniae to cefoperazone / sulbactam ,pip‐eracillin/tazobactam ,imipenem ,meropenem ,cefotetan and amikacin was lower and less than 15 .0% ,the resistance of ESBLs‐produ‐cing strains to most antibacterial drugs was significantly higher than that of non‐ESBLs producing strains (P< 0 .05) .Conclusion Klebsiella pneumoniae isolated from the patients with coexisting pulmonary TB and DM complicating lower respiratory tract infec ‐tion in this hospital has the high detection rate of ESBLs producing strains and strong drug resistance ,therefore clinic should strengthen the ESBLs detection and drug resistance monitoring for preventing the generation of multi‐drug resistance .In the treat‐ment of its infection ,the first choice is containing enzyme inhibitors and carbapenems antibacterial drugs .
3.Effect of preemptive analgesia of katamine and clonidine on postoperative pain and stress response
Yingjun GUAN ; Ke PENG ; Zhenshan YAN
Chinese Journal of Primary Medicine and Pharmacy 2009;16(1):16-17
Objective To observe the preemptive analgesia effects of katamine and elonidine, and to find out the influence of preemptive on stress responses. Methods 36 patients with hysteromyoma undergone hysteromyomec-tomy were randomly assigned to three groups (n = 12 each group) :group Ⅰ , control group, without preemptive analge-sia,the patients in control group were given continous epidural analgesia with 2% lidoeaine 12 - 14ml. Group Ⅱ ,the patients were injected 0. 6mg/kg katamine into epidural analgesia 30 minutes before operation. Group Ⅲ,the patients were injected 0. 6mg/kg katamine and 1.5μg/kg clonidine into epidural analgesia 30 minutes before operation. The patients in three groups were recorded VAS score on 2h ,4h ,6h, 12h ,24h after operation, also recorded the change of epinephrine(E) and norepinephrine(NE) and sensation and movement recovery time after operation. The side effects such as dizziness nausea,vomit,and exited talking were observed during the operation. Results The VAS score were significantly different between group Ⅰ ,Ⅱ and Ⅲ. The levels of E and NE in plasma in group Ⅰ were increased more than group Ⅱ and Ⅲ within 24 hours after operation, also there is significant difference in group Ⅱ compared with group Ⅲ in T1 ,T2 ,T3. The time of sensation and movement recovery were remarkably longer in group Ⅲ com-pared with group Ⅰ and Ⅱ, showing significant difference. There were no significant difference in side effects after operation in three groups. Conclusion The preemptive analgesia of kutamine and colnidine can relieve the pain of lower abdominal surgery and stress response after operation,and it do not increase the side effects.
4.Application of LVIS stent-assisted coil embolization in intracranial wide-neck small aneurysms:clinical analysis of 32 cases
Liming QIU ; Yingbiao HONG ; Jiebo CAI ; Zhenshan WANG ; Hui PENG
Chinese Journal of Primary Medicine and Pharmacy 2017;24(14):2110-2113
Objective To discuss the application effect of LVIS stent-assisted coil embolization in intracranial wide-neck small aneurysms.Methods The clinical data of 32 patients with intracranial wide-neck small aneurysms treated with stent-assisted coil embolization were analyzed retrospectively and evaluated.Results In 32 cases,the embolization grade was Raymond Ⅰ in 23 cases,Raymond grade Ⅱ in 7 cases,and Raymond Ⅲ in 2 cases.The successful embolization rate was 93.8%.No aneurysm was ruptured during embolization.One patient had thrombotic event in the surgery,but the occluded artery was recanalized after the treatment of immediate thrombolysis.Disorder of contralateral limb's activity and confusion were appeared in two patients after surgery.The symptoms improved by giving clopidogrel,aspirin and increasing the dosage of nimodipine.All the survival patients recovered well after 6 months of follow-up.No recurrence of aneurysm was confirmed by DSA and parent artery was patent.Conclusion Lvis stent is simple to be operated and has various models,suitable for most intracranial aneurysms,showing good performance.It suits embolization therapy in intracranial wide-neck small aneurysms,but the strong thrombosis should be valued.