OBJECTIVE:To provide reference for rational use of TCM injection in the clinic. METHODS:Retrieved from CNKI,VIP,Wanfang database and PubMed database,literatures about top 10 TCM injections in the list of report number stated in 2014 CFDA ADR monitoring report were researched in recent 30 years. By literature retrospective study,ADR/ADE induced by TCM injection were analyzed. Combining with post-marketing drug safety re-evaluation and rationality study,the security of clini-cal use of TCM injection was evaluated. RESULTS:A total of 2013 literatures were retrieved,1354 were. Most organs or systems were involved in ADR,especially cardiovascular system,respiratory system,skin and its appendants. Allergic reaction was main clinical manifestation,among which server ADR was allergic shock. Ten ADR/ADE-inducing TCM injections had the lower consis-tency with instructions in the original diseases,solvent,dosage concentration and compatibility application. Consistency rate of original diseases,solvent and dosage concentration was 78.30%,77.94% and 74.64%;81.73% of them were used individually. CON-CLUSIONS:ADR/ADE induced by TCM injection is serious. It is urgent to improve post-marketing revaluation scheme from the aspects of safety and rationality.

The cultivation of medical humanistic quality is indispensable in the standardized training of pediatric residents, and it is urgent to explore new educational methods to improve their medical humanistic quality level. In this study, 60 standardized pediatricians participated in the standardized training, 36 in the experimental group received innovative interactive medical humanities education, while 24 in the control group were set up to receive traditional medical humanities education. Short-term and long-term test scores were conducted by questionnaire at the beginning of the standardized training and 2 years later. The results showed that there was no significant difference between the experimental group and the control group in the self-scores of professional quality, moral cultivation, communication skills, legal knowledge and innovative spirit (P>0.05) , but the scores of teaching teachers were improved except innovative spirit (P<0.05) . In addition, compared with the control group, the number of pediatricians with professional honor increased, the doctor-patient communication ability improved, the medical disputes reduced, and the family satisfaction improved in experimental group were increased (P<0.05) . These results indicated that innovative interactive medical humanistic education is an effective method to improve the medical humanistic quality of pediatric residents in standardized training.