The paper introduced focally quantitative assessment of rehabilitation of children' s cerebral palsy, for example: evaluation methods and clinical application of muscle force, muscular tone, degree of jount movement children' s main reflex, motion function, self - care oneseff in daily life.

Totally 20 children with cerebral palsy of spastic type, aged 1.5-5.0 years, who were treated in Department of Children Nerve Rehabilitation, Nanhai Maternity and Kid Hospital Affiliated to Guangzhou University of Traditional Chinese Medicine, were selected from March to December 2005. Of them, 11 cases were moderate degree of cerebral palsy and 9 cases were severe. The diagnostic criterion of cerebral palsy referred to the diagnostic criterion established at the Countrywide Special Topic Proseminar of Cerebral Palsy in 2004. The method to diagnose cerebral palsy of spastic type referred to the method of Cerebral Palsy Academy of United States in 1956. Cerebral palsy was clinically characterized by the very brisk reflex of extending. The degree was graded by mild, moderate and severe according to the paralyzed part, mental development, speech development, activity of daily living and complication. The children were promoted to stand and walk by themselves mainly with standing promoting training and with restraining method as complement. The course of treatment was 6 months. The curative effect was evaluated by the abducent angle of the hip joint, the angle of popliteal fossa, the dorsiflexion angle of ankle, and the forth item of gross motor function measure, which were measured before and after the treatment. Theresult showed that the range of motion of 20 children was improved. The score of gross motor function measure of standing item improved evidently. A total of 8 cases had significant effect and 12 cases had valid effect. The total effective rate was 100%.

Objective To investigate the effective management approaches for mental retardation plus epilepsy in children.Method Sodium valproat[15～ 60 mg/（ kg· day)] or nitrazepam[0.5～ 1 mg/（ kg· day） ] and guanmaishu containing hyoscyamine(0.0045～ 0.045 mg/（ kg· day)] as adjuvant were administered for 1.5～2 consecutive years.EEG,three dimensional Doppler ultrasonic examination of cerebral vessels were performed.Result Favorable therapeutic effect was obtained in 25 cases(48.1％ ),good effect in 12 cases(23.1％ ).Conclusion Favorable therapeutic effect of hyoscyamine in epilepsy is correlated with improved cerebral microcirculation,cortical choline receptor blocking ,reduced conduction between synapses.These factors all inhibit onset of epilepsy.

Objective To observe the effect of Chinese Medical massage on the development of cerebral palsy infants. Methods 60 infants with cerebral palsy were randomly divided into treatment group (n=30), who accepted Vojta therapy and Chinese massage, and control group (n=30), who accepted Vojta therapy only, for 3 months. They were assessed with Gross Motor Function Measure (GMFM), Gesell Developmental Schedules (GDS) and Ashworth scale before, 3 months and 6 months after treatment. Results The scores of Dimension A of GMFM, the adaptative, personal social quotient of GDS improved more in the treatment group than in the control group (P<0.05) 3 months after treatment, as well as the scores of Dimension B and C of GMFM, and the scores of Ashworth scale 6 months after treatment (P<0.05). Conclusion Chinese medical massage can further improve the development of motor and social function in infants with cerebral palsy

Objective To explore the effect of specific nursing on quality of life of the parents of children with mental retardation (MR). Methods 160 parents of children with MR and 160 parents of normal children were evaluated with WHO Quality Of Life-BREF (WHO-QOL-BREF). The children with MR were divided into observation group (n=80) and control group (n=80). The control group received the traditional nursing care, and the observation group accepted specific nursing care. The scores of WHOQOLBREF were compared. Results The score of WHOQOL-BREF was lower in the MR group than in the normal group (P<0.01). The score decreased with the aggravation of MR (P<0.001). The score of WHOQOL-BREF was higher in the observation group than in the control group (P<0.01). Conclusion Specific nursing should be given to the parents of children with MR, which can promote their quality of life.

Objective To observe the clinical efficacy of needling the meridian muscle regions in treating the lower limb spasm in spastic cerebral palsy.Method Eighty patients with spastic cerebral palsy were randomized into a treatment group and a control group, 40 cases in each group. The two groups were both intervened by conventional rehabilitation. Besides, the treatment group was given acupuncture at the meridian muscle regions including Chengshan (BL 57) point and the point 1 cun above the upper margin of the Achilles-tendon attachment, while the control group was given acupuncture majorly at points from the Yangming Meridian of the affected lower limb. The modified Ashworth Scale (MAS), Composite Spasticity Scale (CSS), and Gross Motor Function Measure (GMFM) were evaluated before intervention and after 3 treatment courses.Result The MAS, CSS, and GMFM scores were significantly changed after intervention in both groups (P<0.01). After treatment, the MAS, CSS, and GMFM scores of the treatment group were significantly different from that of the control group (P<0.05).Conclusion Needling the meridian muscle regions can effectively improve the lower limb spasticity in spastic cerebral palsy, and it can help correct clubfoot and enhance the gross motor function.

Objective To investigate the effect of nerve growth factor(NGF)injection solution on immunosuppression in mice.Methods The immunosuppressed mice were induced by cyclophosphamide(Cy,80mg/kg,sc).The immunomodulatory effects of the drug were measured by cleaning carbon particle method,simple diffusion method,delayed type hypersensitivity(DTH),3H-TdR entering method and indirect immunofluorescence assay.Results The k value;a value,the level of serum IgG and ear swelling were remarkably decreased by NGF injection [0.01,0.1 mg/(kg? d)?10d,im].In addition,the number of L3T+4 Cells of peripheral blood and the ratio of L3T+4/Ly-2+ cell increase.Conclusion NGF has an enhanced effect on experimental immunosuppression in mice,which provides a theoretical basis for NGF treating tumor patients with nervous injure by chemotherapy or radiotherapy.

Objective To observe the effect of acupuncture at lumbar Jiaji (EX-B 2) points plus botulinum toxin injection on the seated function of patients with spastic cerebral palsy.Method Sixty patients aged 1-4 years old with spastic cerebral palsy were randomized into a treatment group and a control group, 30 in each group. The treatment group was intervened by acupuncture at lumbar Jiaji (EX-B 2) points plus botulinum toxin injection, while the control group was by conventional acupuncture plus botulinum toxin injection. After 3 treatment courses, the seated function zone (zone B) of Gross Motor Function Measure (GMFM) was used for evaluation, and the clinical efficacies were compared.Result Respectively after 1, 2, and 3 treatment courses, the total effective rates were 46.7%, 73.3% and 83.3% in the treatment group, versus 33.3%, 46.7% and 60.0%. There were significant differences in comparing the total effective rate between the two groups after 2 and 3 courses (P<0.05). After the first treatment course, the seated function score of GMFM was significantly changed in both groups (P<0.01). After the second course, the seated function score was significantly different from that after the first course in both groups (P<0.01). After the third course, the seated function score was significantly different from that after the second course in both groups (P<0.01). There was a significant between-group difference in comparing the changes of the seated function score during the second treatment course (P<0.01). There was a significant between-group difference in comparing the changes of the seated function score during the second treatment course (P<0.05). Conclusion Acupuncture at lumbar Jiaji (EX-B 2) points plus botulinum toxin injection can produce a more significant efficacy in improving the seated function of patients with spastic cerebral palsy.

ObjectiveTo observe the treatment efficacy of needling LIN’s three temporal acupoints in treating children with autism by using a randomized controlled study method.MethodSixty-eight patients with autism were randomized into an observation group and a control group. Because of dropouts and rejects, 33cases were finally recruited into the observation group, and 32 into the control group. The two groups both received speech training and special education. In addition, the control group received acupuncture at Shenting (GV24), Benshen (GB13), Sishenzhen (Extra), Emotional zone, Speech zone 1, Speech zone 2, and Speech zone 3; while the observation group received acupuncture at LIN’s three temporal acupoints based on the points selected in the control group except for Speech zone 3. Twisting needles and electroacupuncture were also applied in both groups. The treatment was performed once every other day, 10 sessions as a treatment course, with a 15-day interval between two courses, and the therapeutic efficacy was evaluated after 3 courses. Gesell test and Autism Behavior Checklist (ABC) were adopted for evaluation before and after the intervention.ResultBefore treatment, there were no significant between-group differences in comparing the social adaptation, speech and social intercourse ability from Gesell test and ABC score (P>0.05); after treatment,the social adaptation, speech, intercourse ability, and ABC scorewere significantly improved in both groups (P<0.01);there were no significant between-group differences in comparing the social adaptation and speech ability (P>0.05), while theimprovement of social intercourse ability and ABC scoreinthe observation group were more significant than thatinthe control group (P<0.05). ConclusionNeedling LIN’s three temporal acupoints possibly has a specialtreatment effect in improving social intercourse ability and abnormal behavior in autism patients.

Objective To discuss the clinical characteristics and efficacy analysis of children with cerebral palsy and neuronal migration disorders (NMD) by retrospective analysis. Methods From June, 2005 to June, 2015, 32 children with cerebral palsy and NMD were en-rolled as NMD group, while 60 children with cerebral palsy with periventricular leukomalacia (PVL) as PVL group. Both groups received comprehensive rehabilitation for three months. Their clinical classification, complications of epilepsy or epileptiform discharges, the score of Gross Motor Function Measure (GMFM), and development quotient (DQ) were compared, as well as the follow-up results of six months. Results There was significant difference in the clinical classification of cerebral palsy between two groups (χ2=24.529, P<0.001). The inci-dence of epilepsy and epileptiform discharges was higher in NMD group than in PVL group (χ2>4.605, P<0.05). After treatment, the score of GMFM improved with time in both groups (Ftime=6.850, P=0.010), and was significantly lower in NMD group than in GMFM group (Fgroup=29.885, P<0.001);the scores of DQ in all the functional areas improved with time in both groups (Ftime>25.041, P<0.001), and were signifi-cantly lower in NMD group than in GMFM group (Fgroup>32.347, P<0.001). Conclusion Children with cerebral palsy and NMD are charac-terized by mental retardation, epilepsy and spastic hemiplegia, and poor outcome.