1.RNA Sequence-structural Alignment Based on Quantum Evolutionary Algorithm
Progress in Biochemistry and Biophysics 2006;0(09):-
As a classical problem of computational molecular biology, the multiple sequences alignment is also important foundational process. RNA is one of biological polymer, and is different from protein and DNA that the secondary structure of RNA is more conservative than its primary sequence. Therefore, RNA multiple sequences alignment require not only information of sequences, but also information of secondary structures which those sequences will form. Here, a program——QEA-MRNA, which based on quantum evolutionary algorithm(QEA) to align RNA sequences, is proposed. The program introduce a full crossover operator and a fitness function which considering the information of RNA premary sequence and secondary structure, and improving on prematurity controling and the convergent speed. The effectiveness and performance of QEA-MRNA are demonstrated by testing cases in BRAliBase.
2.Brain Structural Basis For Autobiographical Memory
Chinese Journal of Clinical Psychology 2000;0(04):-
Autobiographical memory (AM) is the memory of personal events. At present, autobiographical memory has become another upsurge of memory research after implicit memory. Researches of the brain -based structure for autobiographical memory have also been fruitful, this paper which combined with recent researches reviewed the brain structural basis of autobiographical memory.
3.Confirmatory factor analysis of armymen's mental quality scale
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(7):658-660
Objective To analyze the structure of Armymen' s Mental Quality Scale. Methods Army-men's Mental Quality Scale was administrated to 1426 Chinese armymen in five areas of China,and quantitative methods,such as exploratory factor analysis ( EFA), confirmatory factor analysis ( CFA) was adopted . Results (1) Exploratory factor analysis showed that the 15 factors of armymen' s mental quality can explain 58.328% of total variance. (2)Fit indexes of 15-factor structure model were all consistent with model fitting condition. (3) One factor two and five factor one model of mental quality fitted well. The structure of armymen' s mental quality include 5 dimensions (concretely 15 factors):aptitude,loyalty,bravery,self-confidence and willpower respectively. The aptitude was comprised of judgment, decision-making and response; the loyalty consists of patriotism, dedication and responsibility; the bravery was constituted of determination,steadiness and constancy;the self-confidence consists of imperturbation,independence and team spirit;the willpower consists of adaptability,adjustment and endurance. Conclusion The structure model is reasonable and Armymen' s Mental Quality Scale has good structural validity.
4.Establishment of mental quality scale norms for servicemen in Chinese PLA and analysis of their application
Journal of Third Military Medical University 2003;0(13):-
Objective To establish the morms of mental quality scale for servicemen in Chinese PLA.Methods A total of 7 124 servicemen were randomly sampled from Chinese PLA.Their mental quality was assessed based on the "mental quality scale" we previously established by correlation,regression,variance and student's t test analysis.Results A significant difference existed in mental quality of servicemen,which can be greatly influenced by different services,official ranks,and lengths of military service.Four norms,including a total norm,a service norm,a rank norm,and a military service length norm,were accordingly established,which can be used as the objective criteria for the assessment of mental quality of servicemen in Chinese PLA.A significant difference was found in mental quality of servicemen between the services,official ranks,and lengths of military service (P
5.Application of Competency-based Education in Traditional Chinese Rehabilitation Therapy
Feng YAN ; Jianmei WANG ; Zhengzhi WANG
Chinese Journal of Rehabilitation Theory and Practice 2012;18(11):1098-1099
Objective To explore the effect of competency-based education on course of Traditional Chinese Rehabilitation Therapy.Methods 2 sophomore classes of rehabilitation technology were as the control group and the reform group. The control group was taught with traditional model, while the reform group were taught with the competency-based education. The achievement of these groups were compared. Results There was not significant difference in the theoretical test, but was in the skill test and questionnaire score between the groups (P<0.05). Conclusion The competency-based education can improve the performance of students studying Traditional Chinese Rehabilitation Therapy.
6.Study on Different Proteomics of Denuded tongue coating
Xiaoli ZHANG ; Zhengzhi WU ; Jiguo WANG
International Journal of Traditional Chinese Medicine 2008;30(5):323-325,366
Objective To investigate the microbiostatic mechanism of denuded tongue coating, Proteomic methods were used to find differential expression proteins in denuded tongue. Methods The total protein of normal or denuded tongue coating was separated by means of immobilized pH gradient-based two-dimensional gel electrophoresis (2-DE). The differential expression protein was analyzed by using ImageMaster 2D analysis software. Image analysis software was used for comparative analysis to find differential expression proteins; Mass spectrometry (mass spectrometry) was applied to get the corresponding peptide fingerprint (peptide mass finger print_ PMF). Search the database to identify differences in protein.Results Establish two-dimensional gel electrophoresis for normal and denuded tongue; Segregation analysis on four groups of proteome of tongue coating showed that gel could be detected in the protein spots at 1082=t=105 and 1143±140 respectively; Compared with normal group, there are eight points of protein expression being regulated upward and seven points down.Altogether 9 differences in protein expression were identified. Conclusion The sound resolution and repeatability Two-dimensional electrophoresis silver staining pattern were established; Some differences in protein expression related to denuded tongue were identified.
7.Relationship of depression, automatic thoughts and personality in medical college students
Tao WANG ; Naiwen WANG ; Hongqun HU ; Zhengzhi FENG ; Yunbo LIU
Journal of Third Military Medical University 1988;0(05):-
Objective To explore the relationships of depression status of medical college students with their automatic thoughts and personality. Methods A total of 1 440 medical college students were tested by self-rating depression scale (SDS), automatic thoughts questionnaire (ATQ) and Eysenck personality questionnaire (EPQ). Results ①27.5% medical college students had different degree depressive mood. ② Compared with the non-depression group students, the depression group had higher scores in ATQ, EPQ-N(neurosism) and EPQ-P(psychoticism), lower scores in EPQ-E(extroversion), EPQ-L(lie) (P
8."Exploration on Correspondence between Food Efficacy and Body Constitution Types under the Guidance of ""Donguibogam"""
Tianhong WANG ; Yi ZHANG ; Weiwen LIANG ; Zhang WANG ; Zhengzhi CUI
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(1):116-122
Donguibogam was introduced from traditional Chinese medicine (TCM) instead of the local representa-tive work of the Democratic People's Republic of Korea (DPRK). It is also the concrete manifestation of theories of different schools of doctors according to Dr. Xu Jun's medical thoughts. In this paper, from Dr. Xu's advocacy to Taoism and the concept of aftercare spirit, the exploration was made on health cultivation for different body constitu-tions. According to the health cultivation effects of the medicinals and edible food, the focus was made on the sys-tematic collation and induction of more than 1 400 kinds of herbs contained in the soup liquid from papers in three volumes. The medicinals were divided into eight categories, which were benefiting qi, nourishing yin, tonifying yang, clearing heat and promoting dieresis, drying dampness and resolving phlegm, promoting blood circulation for remov-ing blood stasis, dispersing stagnated liver qi, nourishing blood for hemostasis. Donguibogam specified the health cultivation concept from the correspondence between the body constitution and the medicinal performance. It has a certain guiding significance to the current health cultivation.
9.A preliminary study on the curriculum model for master degree graduate students of medical psy-chology
Yichao WANG ; Juan JIANG ; Zhengzhi FENG ; Yungui WANG ; Yue WU
Chinese Journal of Medical Education Research 2016;15(11):1104-1109
Medical psychology master's degree graduate student course mainly includes basic cour-ses, professional courses and psychological skills training, professional practice skills learning and scientific research quality training. Due to the constraints of discipline development starting late, teachers being rela-tively weak and other objective factors, in curriculum setting, there exist problems of unclear objectives, confusing the primary with secondary, unclear standard, lacking principles, and in particular, there are obvious deficiencies in the training and cultivation of students' ! professional skills . Based on the above objective problems, we made preliminary discussion on the training objectives, the main problems, curricu-lum setting, assessment standards and principles to follow, in order to achieve the purpose of cultivating high-level application-oriented talents through curriculum design and teaching practice.
10.Puzzles and solutions of the cultivation of medical psychology undergraduates
Yichao WANG ; Juan JIANG ; Zhengzhi FENG ; Yungui WANG
Chinese Journal of Medical Education Research 2014;(7):657-660
As an emerging discipline, medical psychology undergraduate education is restricted by many conditions, such as subject orientation, training objectives, curriculum setting, teaching con-tent, teaching material system, teaching mode, professional practice, assessment and graduation and so on. To improve the training quality and level, the paper explores the corresponding education strat-egy from the aspects of subject orientation, training objectives, curriculum and teaching contents. For example in the subject orientation and training objectives the principle of paying equal attention to medical and psychological disciplines is reflected, and at the same time the construction of the curricu-lum, teaching contents and curriculum system is strengthened to highlight the psychology and medical integration and mutual penetration. In the link of teaching, professional practice, graduation appraisal and award process, practical skills training and assessment are focused on, and the relevant national qualification examination is taken as award criteria.