1.Prophylactic effects of intra-articular injection of salvia miltiorrhiza on joint adhesions in rabbit knee joints
Kan DUAN ; Changshen YUAN ; Hongyi YAO ; Yuxiang LIU ; Zhengzhi LIU
Orthopedic Journal of China 2009;17(22):1739-1742
[Objective]To investigate the prophylactic effects of intra-articular injection of salvia miltiorrhiza on joint adhesion. [Methods]Twenty-four Japanese male rabbits were randomly divided into 3 groups.All right hind knees were made in this way: the auterior wall of suprapatellar bursae was scraped, the posterior wall of suprapatellar bursae and the infrapatellar fat pad were cut off. Each knee was injected with physiological saline 0.3 ml for group A, sodium hyaluronate injection 0.3 ml for group B, and salvia miltiorrhiza injection 0.3 ml for group C. All right hind knees were immobilized in the extension position with a long leg plaster cast for 4 weeks, and injected weekly.[Results]After 4 weeks, the joint movement range in group B or C was larger than that in group A (P<0.01), and there was no significant difference (P>0.05)compared to group B and group C. The scoring of joint adhesions in group B or C was smaller than that in group A (P<0.01), and there was no significant difference(P>0.05)compared to group B and group C. The scoring of histological changed of the synovial membrane in group B or C was smaller than that in group A (P<0.01), and there was no significant difference(P>0.05)compared to group B and group C.Total collagens content of the synovial membrane in group B or C was smaller than that in group A (P<0.01), while that of group C was less than in group B(P<0.01). [Conclusion]Similarly to sodium hyaluronate, salvia miltiorrhiza can effectively prevent joint adhesions.
2.The implicit memory of individual depression in percept-driven process under the influence of sad mood induction
Qingying LIU ; Zhengzhi FENG ; Feng WANG ; Jiawen LI
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(5):444-447
Objective To investigate the effect of sad mood to implicit memory of depressed individuals under the condition of percept-driven process. Methods Using the percept-driven implicit paradigm improved by Paller,26 depression subjects and 25 normal subjects completed study-test task and reported the gender of different emotional faces. Results ①There were main effects of time(F = 4.61, P<0.05)and mood state(F= 21.61, P <0.05) ,significant interaction of time and emotion(F = 4. 13, P<0. 05) ,no significant difference of group on visual analogue scale(VAS) mood ratings. ②Among the accuracy rate of subjects' gender judging to different emotional faces,there were significant main effects on time(F = 4.12, P<0.05)and experiment type (F = 20.55, P < 0.05) , and there was significant interaction of time and experiment type (F=31.72,P<0.05). ③Further simple effects analysis showed that the positive((80 ± 13)%vs(92 ± 10)% , F=65.06, P<0.05) ,negative((58 ± 12)%vs(91 ±10)%,F=10.00,P<0.05),neutral((84±16)%vs(88±9)%, F= 12.49, P < 0. 05) faces when the presentation time was 3600ms in experiment type had significant simple effects; the positive ((76 ± 12)%vs(85±10)%,F=54.72, P<0.05) ,neutral((82 ± 10)% vs(80 ± 10)% , F = 54.57, P<0.05)faces when the presentation time was 300 ms in experiment types had significant simple effects, while the accuracy of neutral faces had significant simple effect between the two groups. Conclusion Sad mood enhance the implicit memory of both depressed and normal subjects to positive and negative faces,and the accuracy rate in implicit processing to neutral faces of depressed group were lower than that of normal group.
3.Incidence of depression in patients with advanced malignancy and its effect on quality of life
Mei YE ; Zhengzhi FENG ; Keyu LIU ; Huoming CHEN
Cancer Research and Clinic 2013;(4):260-262
Objective To investigate the incidence of depression in patients with advanced malignancy and its effect on quality of life.Methods Patients with advanced malignancy were evaluated with Beck depression and quality of life questionnaires.The correlation of Beck depression scoring with quality of life was analyzed.Results A total of 230 in-patients with advanced malignancy were enrolled in this study and 213 copies of valid questionnaire were collected.95.3 % (203/213) patients had depression.The Beck depression scoring had positive correlation with body,role,mood,cognition,society,vomiting,pain,dyspnea,agrypnia and appetite (all P < 0.05),and had negative correlation with total health factors (r =-0.296,P < 0.01).Conclusion Depression is prevalent in patients with advanced malignancy and correlated with quality of life.Therefore,psychological interventions are needed to relief depression and improve quality of life.
4.Relationship of depression, automatic thoughts and personality in medical college students
Tao WANG ; Naiwen WANG ; Hongqun HU ; Zhengzhi FENG ; Yunbo LIU
Journal of Third Military Medical University 1988;0(05):-
Objective To explore the relationships of depression status of medical college students with their automatic thoughts and personality. Methods A total of 1 440 medical college students were tested by self-rating depression scale (SDS), automatic thoughts questionnaire (ATQ) and Eysenck personality questionnaire (EPQ). Results ①27.5% medical college students had different degree depressive mood. ② Compared with the non-depression group students, the depression group had higher scores in ATQ, EPQ-N(neurosism) and EPQ-P(psychoticism), lower scores in EPQ-E(extroversion), EPQ-L(lie) (P
5.MORPHOLOGICAL STUDY OF VIMENTIN IN SYNOVIAL CELL IN VITRO
Zhengzhi ZHANG ; Zhengjin LIU ; Shizhen ZHONG ; Guoying WANG
Acta Anatomica Sinica 1955;0(03):-
The pattern and distribution of vimentin intermediate filament in synovial cell in vitro were observed by means of immunohistochemistry,confocal scanning laser microscopy (CSLM) and three-di-mentional photograph reconstruction on adherent cell analysis and sorting (ACAS 570). The result showed that vimentin presented spongy stero-structure in whole cytoplasmic space. The reconstructed three-dimentional photograph was similar to the appearance of the cultured synovial cell. The relationship between the distribution of vimentin and the morphological change of cultured synovial cell in different growth period was discussed in this paper.
6.Influence of repeatedly suprathreshold and subthreshold presentation of sad face on attention bias of college students with depressive symptoms
Rong CHEN ; Zhengzhi FENG ; Yang'e LIU ; Qin DAI ;
Chongqing Medicine 2016;45(33):4636-4638,4642
Objective To explore the influence of repeatedly suprathreshold and subthreshold presentation of sad face on the attention bias of college students with depressive symptoms.Methods Five hundreds college students were extracted by using the cluster sampling method.The Beck Depression Inventory(BDI)and Self-rating Depression Scale(SDS)as the screening tool were applied to select the healthy control group(C),low-level depression group(B)and high-level depression group(A),20 participants in each group.Twenty neutral faces and 52 sad faces were selected from the emotional faces library researched and prepared by the Institute of Psychology of Chinese Academy of Sciences.Each face was suprathresholdly(1 000 ms)and subthresholdly(14 ms)presented four times to the participants.In the point detection task,the scores of response time,correction rate and attention bias of 3 groups to the emotional faces were recorded.Results (1)There was no statistically significant difference in the correction rate for 4 times suprathreshold and subthreshold presentations of sad faces between three groups;(2)The average response time of the fourth superathreshold and subthreshold presentation of sad faces in the group A was significantly lower than that of the first three times,the difference was statistically significant(P<0.01),but the times of sad emotional face presentation had no statistically significant difference between the group C and B(P>0.05);(3)compared with the group C,for the suprathesholdly presented sad face,the group A had significant a main effect in the aspects of average score of attention bias and sad emotional face presentation times(F=12.032,P<0.05;F=91.637,P<0.05),and had a significant interaction effect among the duration and times of presentation and group types(F=16.766,P<0.05);(4)the group A showed significant attention bias of suprathresholdly presented sad faces at first,second and third time of presentation,but lost the bias at the fourth time.Conclusion The fourth time of sad face presentation could eliminate the attention bias of college students with high-level depression.
7.The characteristics of the fear emotion enhanced regulation of the soldiers with different mental quality levels
Juan JIANG ; Xintao SONG ; Jing TU ; Keyu LIU ; Tingting TUO ; Zheng DU ; Zhengzhi FENG
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(2):108-111
ObjectiveTo investigate the characteristics of autonomic nervous response of armymen with different mentalqualityuse the enhanced emotion regulationstrategies during fear emotion processes.Methods Mental Quality Questionnaire of Armymen was used to select participants from 818 armymen,screening out 30 armymen with low mental quality,30 armymen with moderate and 30 armymen with high.With elicitation of fear emotion,the participants adopted enhance emotion regulation strategies (cognition emphasis and emotion catharsis),and their blood volume pulse( BVP),skin conductance( SC ),normalized high frequency spectral component(HFnorm),standard deviation of all normal intervals(SDNN) and the recovery time of BVP and SC were recorded.Results ( 1 ) The different mental quality of army men activity in the autonomic physiological changes were not significant differences in resting state.(2) When using the cognition emphasis,the SC of different mental quality of armymen were reduced,and low mental quality of armymen( ( -0.67 ± 1.05 )μ.Ω),moderate mental quality of armymen ( ( - 0.49 ± 0.75 ) μΩ) had larger SC than high mental quality of armymen ( ( - 2.16 ± 2.18 ) μΩ ) ;high mental quality of armymen( ( - 2.17 ± 8.96) nU ) had lower HFnorm than the control( ( 6.96 ± 7.08 ) nU ).When using emotion catharsis,high mental quality of armymen ( ( 1.95 ± 6.58 ) nU ) had lower HFnorm than the control( (6.96 ±7.08)nU).(3)When using the cognition emphasis,low mental quality of armymen ((65.50 ±43.43 )s) had longer recovery time of BVP than high mental quality of armymen( (26.50 ± 25.72)s).When using emotion catharsis,low mental quality of armymen( (71.50 ± 48.36)mm Hg)had longer recovery time of BVP than high mental quality of armymen ( ( 21.00 ± 35.50 ) mm Hg) ; low mental quality of armymen ( ( 103.50 ± 38.01 ) s)had longer SC than moderate( (63.50 ±48.59)s) and high mental quality of armymen( (61.50 ±33.09) s).Conclusion The ability to regulate sympathetic in low mental quality group is weaker than the high mental quality group,although sympathetic can be suppressed when enhanced emotion regulation are adopted.
8.The relationship and the path model construction among stressful life events, social support and depression in People′s Liberation Army
Ran YU ; Liying GAN ; Xuecheng LI ; Zhengzhi FENG ; Guangyi ZHU ; Keyu LIU
Chongqing Medicine 2014;(15):1907-1909,1957
Objective To investigate the relationship among stressful life events ,social support and depression through researc‐hing a large number of Chinese army men ,then discovered the social psychological mechanism of the depression .Methods 11 ,400 officers and soldiers were tested with three scales ,the center for epidemiologic studies depression scale ,life events scale and social support scale .The differences between groups were determined with the variance ,SPSS 18 .0 software and AMOS7 .0 were used to analyse and build model .In addition ,we built the path model of life events and social support on depression with AMOS 7 .0 soft‐ware .Results (1)There is a significant positive correlation between Chinese soldiers depression levels and life events (r=0 .382 , P<0 .01) .(2) There is a significant negative correlation between Chinese soldiers depression levels and the social support (r= -0 .379 ,P<0 .01) .(3) It was established the path model of life events ,the social support and depressive symptom level .Con‐clusion Depressive symptom is related to the military life events ,which may predict the occurrence of the depression .Moreover ,so‐cial support ,a protective factor for mental health ,can relieve the depression of officers and men .
9.Metacarpal fascial spaces of the hands by computerized three-dimensional reconstruction: Applied anatomic characteristics
Xiaowei LIU ; Guiyou BAI ; Bingsheng WANG ; Zhengzhi ZHANG ; Hua SUN ; Chuandong LU
Chinese Journal of Tissue Engineering Research 2007;11(22):4436-4439
BACKGROUND: The metacarpal fascial spaces of hand are the potential structure that is not virtual, so that difficulties are presented in diagnosis and treatment of diseases of the metacarpal fascial spaces of hand. In order to solve the difficulties,anatomical borderline and abut relationship of the metacarpal fascial spaces of hand have to be sufficiently understood. OBJECTIVE: The borderline and abut of the metacarpal fascial spaces of hand were detailedly observed and researched by fresh cadaveric dissection, thin sectional anatomy and computer image recognition technology, and the 3-D reconstruction technology was utilized to reconstructed the metacarpal fascial spaces in this paper, so the abut relationship of the metacarpal fascial spaces of hand could be displayed, and the detailed anatomical data of imaging diagnosis and surgical treatments of disease of the fascial spaces of hand could be provided. DESIGN: Repeated measuring design.SETTING: The 251 Hospital of Chinese PLA and Central Laboratory of the Third Military Medical University of Chinese PLA. MATERIALS: Twelve adult fresh cadaveric hands which involved six right hands and six left hands and wrist joint, had no organic damage by naked observation, provided by the Department of Anatomy, the Third Military Medical University of Chinese PLA, among one right hand and one left hand were waiting for being mill-cut and thin cross-section dissected and imaging reconstructed. Among ten hands were observed by fresh cadaveric anatomy. METHODS: The trial was carried out in the 251 Hospital of Chinese PLA and Central Laboratory and Department of Anatomy of the Third Military Medical University of Chinese PLA from May 2003 to February 2006. Based on the gross anatomy, thin cross-section anatomy, visible human and virtual human technology theory, the metacarpal fascial spaces of hand were three-D reconstructed in microcomputer.MAIN OUTCOME MEASURES: Anatomical borderline and about relation of the metacarpal fascial spaces of hand. RESULTS: Display of observation result of adjacent and dimension of the midpalmar space and the thenar space by fresh cadaveric anatomy combined with thin cross-section anatomy, computer image recognition technology, and the 3-D reconstruction technology: The anterior borderline of the MPS was the digital flexor tendons of middle finger, ring finger, little finger and the 2nd lumbrical muscle (LM), 3rd LM, 4th LM; the posterior borderline was the palmar interosseous fascia before 3rd palmar bone, 4th palmar bone, 5th palmar bone and corresponding interosseous muscles; the lateral borderline was the palmar intermediate septum; the medial borderline of the MPS was the medial intermuscular septum of palm. In addition, the distal section of the MPS which was separated into three little spaces by two septums of connective tissue, and 3rd 4th, 5th digital flexor tendon and 2nd, 3rd, 4th LM were respectively contained by the three little spaces. The proximal of this space opened to the posterior space of antebrachial flexor by the carpal canal; the distal of this space opened to 2nd, 3rd, 4th web space (WS) by 2nd, 3rd, compartment of 4th LM, and continuously the dorsal subcutaneous space and the subaponeurotic space. The anterior borderline of the TS was the 1st digital flexor tendon and the 1st LM; the posterior borderline was the fascia of abductor pollicis; the medial borderline was the palmar intermediate septum (PIMS); the lateral borderline was the tenden sheath of flexor pollicis longus and the lateral intermuscular septum of palm. The distal of this space opened to 1st WS by compartment of the 1st LM, and continuously to the dorsal subcutaneous space and the subaponeurotic space; the proximal of the TS was close.CONCLUSION: The proximal of the thenar space is close, the distal section of the metacarpal fascial spaces is separated into three little spaces, and the computerized three-D renconstruction of the fascial spaces of hand can provide some guidance for imaging diagnosis and surgical treatments.
10.Development and reliability, validity analysis of overgeneral autobiographical memory questionnaire
Wen JIANG ; Keyu LIU ; Zhengzhi FENG
Chinese Journal of Behavioral Medicine and Brain Science 2020;29(9):847-853
Objective:To develop overgeneral autobiographical memory questionnaire(OGMQ) and test its reliability and validity.Methods:Through literature search, expert opinions and group discussion the initial items of the questionnaire were formed. A random cluster method was adopted to select 1 911 college students for the preliminary test.Totally 1 840 valid questionnaires were obtained, and 920 of which were assessed for exploratory factor analyses and 920 of which were assessed for confirmatory factor analyses and reliability and validity analysis. Thirty subjects with depression and 30 normal subjects were selected to test its criterion validity.Results:The questionnaire consisted of 19 items, two dimensions (construction, elaboration) and four factors (spatial-temporal factor, control factor, context factor, emotion factor). Exploratory analysis extracted 4 factors and 19 items, KMO (Kaiser-Meyer-Olkin) = 0.905, Bartlett test: χ 2=4 728.134, df=171, P<0.001.Confirmatory analysis showed that the factor loads of spatio-temporal factor and control factor in the construction dimension were 0.770 and 0.539 respectively, while the factor loads of context factor and emotional factor in the elaboration dimension were 0.911 and 0.800 respectively. The questionnaire had good internal consistency reliability (Cronbach α=0.870), structural validity (χ 2/ df=3.550, RMSEA=0.053, GFI=0.944, CFI=0.970, NFI=0.958, IFI=0.970) and criterion validity ( r(OGMQ, AMT)=0.870, r(OGMQ, BDI)=0.507), and it was able to effectively distinguish between depressed and normal groups (AUC=0.795). Conclusion:The OGMQ has satisfactory validity and reliability, and meets the needs of psychometrics, which can be used in depression-related research and practice.