1.Quality as life,metrology as guarantor
Chinese Medical Equipment Journal 2003;0(10):-
This paper introduces the forming of the metrology control network which attracts great attention of the hospital's leadership.The result indicates that the metrology knowledge training is strengthened,its level is raised,and the metrology control becomes more scientific,effective and standardized.Now a new atmosphere appears in our hospital that every staff values and participates in the metrology work.Both the examined rate and qualified rate of the measuring appliances reach 100%.Accurate,reliable,safe and effective measuring appliances are provided for the clinical work.
2.Applied anatomy of the transposition of spine of scapular flap pedicled with thoracoacromial artery
Zhenguang CHEN ; Heping ZHENG ; Fahui ZHANG
Chinese Journal of Microsurgery 1998;0(01):-
Objective To provide the anetomic base for the transposition of spine of scapular flap pedicled with thoracoacromial artery Methods The course, branches and distribution of thoracoacromial artery were observed on 40 adult cadaver specimens Results The main branch of thoracoacromial artery was the acromial branch Its length was (5 1?0 1) cm, the originated diameter was (1 2?0 2) mm The deltoid muscular branch went outward intermuscular ditch between deltoid muscle anspectoralis major muscle, and anastomosed with anterior humeral circumflex artery constantly besides distributing to deltoid muscle and pectoralis major muscle, its diameter was (1 9?0 2) mm, the length form the originated dot to the entrancing muscular dot of deltoid muscle or pectoralis major muscle was (4 8?0 5) cm or (3,2?0 4) cm respectively Conclusion The transposition of lateral segment spine of scapular flap pedicled with the acromial branch of thoracoacromial artery or deltoid muscular branch acromial branch may be designed for repairing proximal humerus
3.Transposition of vascularized tarsal bone flaps to repair bone lesions in ankle and foot
Zhenguang CHENG ; Fahui ZHANG ; Guorong YU
Chinese Journal of Microsurgery 2000;0(03):-
Objective To provide a series of surgical approaches for treatment of bone lesions in ankle and foot. Methods Based on the anatomic investigations,vascularized cuboid bone,medial cuneiform bone,navicular bone and lateral part of calcaneum bone grafting were designed for repaired bone lesions in the area of ankle and foot,and applied to 55 clinic cases. Results Forty-eight cases among them were followed up from 1 year to 10 years,4 years and 6 month in average,the results were satisfactory. Conclusion The designed four types of vascularized tarsal bone flaps are easy and reliable for dissection because of their superficial pedicle.
4.Sleep disorders in patients w ith ischemic stroke:pathophysiological mechanisms and treatment
Zhaoyang YAN ; Zhenguang LI ; Pengfei WANG ; Yong ZHANG ; Jiangshan ZHANG
International Journal of Cerebrovascular Diseases 2016;24(11):1039-1044
Sleep disorder is a common complication after is chemicstroke.If it is nottimely diagnosed and treated, it may affect the rehabilitation of stroke and recurrence. The manifestations of sleep disorders have various forms according to the different locations of infarction. For the treatment of sleep disorder after stroke, the method of the combination of drugs and physical therapy is used in clinical practice at present. In recent years, w ith the w idely use of the polysomnography, poststroke sleep disorders can be diagnosed clearly and carefuly. The treatment for sleep disorders after stroke may significantly improve the prognosis of patients.
5.Antiplatelet therapies in ischemic stroke patients with diabetes mellitus or insulin resistance
Zhenguang LI ; Tong WANG ; Jinbiao ZHANG ; Xinghua CUI ; Jiangshan ZHANG
International Journal of Cerebrovascular Diseases 2016;24(10):930-935
Diabetes mellitus is an independent predictor of high platelet reactivity after antiplatelet therapy in patients with ischemic stroke,and the latter is closely related to the increased risk of recurrence of stroke.The mechanisms of high platelet reactivity in patients with diabetes or insulin resistance are associated with a variety of factors.Some circulating molecules can be used as markers for predicting the reactivity of platelets.Monitoring of platelet reactivity after treatment with new antiplatelet agents may provide basis for individualized antithrombotic therapy in ischemic stroke patients with diabetes or insulin resistance.
6.Clopidogrel resistance and its countermeasures in the prevention of ischemic stroke
Jiangshan ZHANG ; Zhenguang LI ; Jinbiao ZHANG ; Chao SUN
International Journal of Cerebrovascular Diseases 2015;23(4):274-280
Clopidogrel can inhibit platelet aggregation and reduce the risk of recurrent stroke.However,it is a great difference in antiplatelet inhibition in different populations.This article reviews the mechanism of clopidogel resistance and its countermeasures in the prevention of ischemic stroke.
7.Evidence-based Guidelines on Medication Therapy for Purulent Meningitis in Children:A Systematic Review
Hongliang ZHANG ; Nan LI ; Zhenguang HUANG ; Yimei LIAO ; Taotao LIU
China Pharmacy 2016;27(21):2948-2950
OBJECTIVE:To systematically review the related evidence-based guidelines of purulent meningitis in children,and to provide evidence-based reference for clinical treatment. METHODS:Retrieved from PubMed,EMBase,CBM,Wanfang Data-base,CJFD and VIP,NGC,GIN,TRIP and websites of domestic and international medical associations and industry bodies,the treatment guidelines about purulent meningitis in children were collected. Evidence-based evaluation was performed after data extrac-tion and quality evaluation. RESULTS:Finally 3 guidelines were enrolled in total,with development time ranging from 2004 to 2012,from USA,Britain and Australia,respectively. All of the recommendations were level B,scope and purpose and clarityshowed the higher scores in AGREEⅡ,more than 70%,and applicability showed generally low scores. Penicillin and cefotaxi-me were recommended in purulent meningitis of neonates,and vancomycin combined with cefotaxime or ceftriaxone were recom-mended for infants and children(it was combined with vancomycin when Streptococcus pneumoniae infection was suspected). The dose and duration of each guideline were certain different,and the period of treatment should be longer in neonates. In addition, the glucocorticoid was recommended in all guidelines. CONCLUSIONS:The recommendations of medicines for the treatment of pu-rulent meningitis are basically unanimous,with no regional difference,but there are some differences about dose and the course of treatment. In addition,the classification criteria of the levels of evidence and recommendation are still suboptimal,which needs fur-ther improvement. And guidelines on purulent meningitis should be improved inrigourandapplicabilityin future.
8.Analysis on illuminated dose level of operators' eyes in imaging quality control test of positron emission tomography
Xianpeng ZHANG ; Haitao YU ; Wei LI ; Zhenguang WANG ; Guoyong DING
Chinese Journal of Radiological Medicine and Protection 2017;37(4):294-297
Objective To investigate the eye lens dose to the operators who tended to test the quality control of positron emission tomography (PET).Methods Before encapsulation and in preparation of point source,line source 1 and line source 2,the two operators were worn with lens thermoluminescence dosimeter each at the left of the left eye,the front of the left eye,between the right eye and the left eye,the left of the right eye,and the front of the right eye.Measurement and analysis were made of the radiation doses to eye lens received by the operators in order to calculate their maximum annual doses.Results The maximum lens dose was 2 439.80 μSv for the test of 5 PETs.There appears to be the same trend in the eye lens doses for the first and second operators.(x2 =15.629-16.155,P < 0.05).The first operator have received higher eye lens dose higher than the second(Z =2.611,P < 0.05).Conclusions The dose to the eye lens for a single PET test is relatively low.
9.Evidence-based evaluation of the effect of mouse nerve growth factor on fracture healing
Hongliang ZHANG ; Zhenguang HUANG ; Yan WEN ; Shuangyi TANG ; Taotao LIU
Chinese Journal of Biochemical Pharmaceutics 2015;37(5):72-76
Objective To evaluate the effect of mouse nerve growth factor on fracture healing.Methods Cochrane library, Pubmed, EMbase, CNKI,VIP,Wanfang Data and CBM were searched for the randomized controlled trials(RCTs)of mouse nerve growth factor on fracture healing from the date of establishment of the databases to May 2014.Three independent rese archers evaluated the included studies using GRADE,according to recommend classification method of GRADE system by three researchers,crtical evaluated and data extracted of the quality of the included studies,which conform to the quality standard of RCT was analyzed by Meta analysis.The extracted data were analyzed by RevMan 5.0 and GRAED proiler.Results A total 5 trials were discovered and all of these were in Chinese.Compared with conventional treatment was improved a lot[MD =-8.74,95%CI( -9.79,-7.68),P<0.0001].However, adverse drug reaction in patients with mouse nerve growth factor were increased[OR =14.66,95%CI(1.89, 113.99),P=0.01].The both outcomes were low quality in the GRADE system.Conclusion Mouse nerve growth factor can improve fracture healing and the side effects will also increase.
10.Correlation between serum cystatin C levels and cerebral microbleeds in patients with acute ischemic stroke
Hairong SUN ; Zhenguang LI ; Xiaohua JU ; Jing WANG ; Jinbiao ZHANG
International Journal of Cerebrovascular Diseases 2015;23(1):11-15
Objective To investigate the correlation between serum cystatin C (CysC) levels and cerebral microbleeds (CMBs) in patients with acute ischemic stroke.Methods The patients with acute ischemic stroke were enrolled.Susceptibility weighted imaging was used to identify the presence of CMBs.Particle-enhanced turbidimetric immunoassay was used to detect the levels of serum CysC.Results A total of 485 patients with acute ischemic stroke were enrolled,including 151 (31.1%) with CMBs.The level of serum CysC of the CMB group was significantly higher than that of the non-CMB group (1.24± 0.13 mg/L vs.1.02± 0.11 rmg/L; t=4.261,P< 0.001).Multivariate logistic regression analysis showed that the increased serum CysC level was an independent risk factor for the presence of CMBs in patients with acute ischemic stroke (each increase in one standard deviation,odds ratio 4.063,95% confidence interval 2.142-8.127; P <0.001).Multiple linear regression analysis showed that the number of CMBs in patients with acute ischemic stroke increased with the increasing serum CysC level after adjusting for other confounders (r2 =0.361,P =0.017).Conclusions In patients with acute ischemic stroke,the serum CysC levels are independently associated with the CMBs,and the number of CMBs increases with the serum CysC level.