1.Influence on the effect of the two kinds of drainage patterns for patients with ventricular hemorrhage
Zhengshan ZHOU ; Haochen ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(1):65-66
Objective To summarize and discuss the clinical results of lumbar catheter drainage auxiliary ventricle drainage surgical puncture on patients with intraventricular hemorrhage about postoperative ADL.Methods The 86 patients with intraventricular hemorrhage admitted to our hospital were randomly divided into two groups,43 patients in control group were given conventional lateral ventricle puncture and continued external drainage,43 patients in observation group were given lumbar catheter drainage auxiliary ventricle drainage surgical puncture based on the conventional treatment.Clinical efficacy were observed,and functional outcomes were evaluated.Results The clearance rate of intraventricular hemorrhage and hospitalized days of the observation group were lower than those of the control group (t =4.23,11.82,all P < 0.05),Quality of life in the observation group was better than that in the control group(x2 =1.73,P < 0.05).Conclusion The clinical result of lumbar catheter drainage auxiliary ventricle drainage surgery for intraventricular hemorrhage in patients is satisfactory and worthy of clinical application.
2.A Research on Zheng Qing-an’s View on Balance of Yin and Yang and It’s Origin and Development
Zhengshan WANG ; Qicheng ZHANG
Journal of Zhejiang Chinese Medical University 2014;(11):1269-1272
Objective]To summarize and clarify the view on Yin and Yang of Zheng Qin-An ,in order to deepen the study on fire-spirit school. [Method]Read the related works of Chen Xiu-Yuan, Liu Yuan, Zheng Qin ’An, Lu ZhuZhi, etc, as wel as related research papers of modern researchers. Then we summarize the view on Yin and Yang of Zheng Qin-An, as wel as it ’s resources and evolution. [Result] Zheng Qin-An advocated the balance of Yin and Yang, didn’t admire Yang and despise Yin. He also had no preference on Yang aided medicine. Zheng Qin-An ’s view on Yin and Yang mainly was affected by Liu Yuan, and significantly different from Chen Xiu-Yuan. Lu Zhu-Zhi inherited the academic point of view of Zheng Qin-An and made some significant changes. After that, fire-spirit school only emphasized the importance of Yang Qi. Developed to the extreme, some fire-spirit school scholars held that al patients were Yang deficiency and al prescriptions should aid Yang Qi. These views had deviated significantly from its founding fathers. [Conclusion]Zheng Qin-An advocated the balance of Yin and Yang, but his successor ’s only emphasis on the importance of Yang Qi, was contrary to the original intention of Zheng Qin-An.
3.Clinical features of familial moyamoya disease in China
Zhengshan ZHANG ; Rui ZHANG ; Lian DUAN
International Journal of Cerebrovascular Diseases 2016;24(2):114-116
Objective To investigate the clinical features of familial moyamoya disease in China. Methods The patients w ith familial moyamoya disease admitted to the department of Neurosurgery, the 307th Hospital of PLA from March 2009 to June 2012 w ere analyzed retrospectively. Results Of 1 108 patients w ith moyamoya disease admitted to the department of Neurosurgery, the 307th Hospital of PLA, 87 patients (7.8%) w ith familial moyamoya disease w ere identified. Familial moyamoya disease w as observed both in the Han nationality and the minority nationalities. The male to female ratio w as 1∶1.02. The age at first onset ranged from 8 months to 59 years. There w ere tw o peak ages -of-onset, 5-9 years and 30-34 years, respectively). The most common initial symptom w as cerebral ischemia (74 .7%). The first degree relatives w ere the most affected in patients w ith familial moyamoya disease (78/87, 89 .66%), in w hich the siblings accounted for most of the disease ( 38/78, 48.72%), and the proportions of mother-to-child inheritance (21/78, 26.92%) and father-to-child inheritance ( 19/78, 24.36%) w ere similar. Conclusions There are tw o peak ages-of-onset, cerebral ischemia is the most common initial symptom, the first degree relatives are the most affected in patients w ith familial moyamoya disease in China.
4.Headache in children w ith moyamoya disease
Rui ZHANG ; Zhengshan ZHANG ; Lian DUAN
International Journal of Cerebrovascular Diseases 2016;24(2):128-130
Headache is one of the most common symptoms in children w ith moyamoya disease. Its related pathogenesis, clinical manifestations, and operation effect remain unclear. This article review s the advances in headache in children w ith moyamoya disease by review ing the related literatures on the study of headache in children w ith moyamoya disease.
6.Clinical Study of Adenosine Triphosphate in Terminal Point Determining of Radiofrequency Catheter Ablation
Zhengshan GAO ; Xiouzhi LI ; Qing ZHANG
Journal of Chinese Physician 2001;0(07):-
3S in 2 cases(5 7%).Ventriculoatrial conduction block was observed in 27 cases(77 1%) and no changes in 6 cases(14 3%) under the pace of right ventricular.Conclusions ATP is a determing index of successful RFCA of AP.However,it is not always reliable,incremental doses of ATP were recommended.
7.Moyamoya disease associated w ith intracranial aneurysm:clinical features, risk factors of hemorrhage and treatment outcomes
Huaitao YANG ; Zhengshan ZHANG ; Lian DUAN
International Journal of Cerebrovascular Diseases 2015;(2):102-106
ObjectiveToinvestigatetheclinicalfeatures,riskfactorsforbleedingandtreatment outcomes in moyamoya disease patients w ith intracranial aneurysms. Methods The clinical symptoms, location and size of aneurysm, treatment and the long-term folow-up results of the moyamoya disease patients w ith intracranial aneurysms w ere analyzed retrospectively. Results A total of 34 moyamoya disease patients w ith intracranial aneurysms (35 aneurysms) w ere enrol ed, including 22 (64.7%) in the intracranial hemorrhage group and 12 ( 35.3%) in the non-intracranial hemorrhage group. Of the 35 intracranial aneurysms, 23 (main artery type 11, peripheral artery type 12) w ere in the intracranial hemorrhage group and 12 (main artery type 11, peripheral artery type 1) w ere in the non-intracranial hemorrhage group. There w ere 29 smal aneurysms and 6 medium aneurysms (al w ere patients w ith hemorrhagic moyamoya disease). The aneurysms w ere mainly peripheral arterial type in the intracranial hemorrhage group, and the aneurysms w ere mainly artery type in the non-intracranial hemorrhage group. There w as significant difference in aneurysm typing betw een the tw o groups ( P= 0.013 ). Tw o patients did not perform encephalo-duro-arterio-synangiosis (EDAS) in the intracranial hemorrhage group, other patients and those of the non-intracranial hemorrhage group performed EDAS. Angiographical reexamination revealed that 3 patients w ith peripheral aneurysm disappeared, and 1 aneurysm recurred after aneurysm embolization, and the remaining aneurysms did not have any change. Long-term fol ow-up show ed that 1 patient died of sudden cerebral hemorrhage at 1 year after procedure in the intracranial hemorrhage group, and the others did not have ischemic or hemorrhagic stroke. The modified Rankin scale scores w ere improved in 21 patients. Conclusions There are differences in moyamoya disease patients w ith intracranial aneurysm typing w ith different clinical manifestations. Moyamoya disease patients w ith intracranial aneurysms are mostly smal aneurysms and they can not temporarily be treated directly and can perform EDAS directly. Intracranial aneurysms after procedure may remain long-term stability, and some peripheral aneurysms may disappear.
8.Clinical features and prognosis of patients with moyamoya disease and renal artery stenosis
Zhengshan ZHANG ; Huaitao YANG ; Rui ZHANG ; Lian DUAN
Chinese Journal of Cerebrovascular Diseases 2015;(4):185-188
Objective To investigate the clinical features and prognosis of patients with moyamoya disease and renal artery stenosis. Methods The clinical data such as the first symptom,intracranial vascular lesions,renal artery lesions,treatment and follow-up results of the 15 patients with moyamoya disease and complicated with renal artery stenosis (RAS group)and the baseline-matched 30 moyamoya diseased patients without renal artery stenosis (MMD group)treated at the Department of Neurosurgery,the 307 th Hospital of People′s Liberation Army from March 2009 to June 2012 were analyzed retrospectively. Results (1)The moyamoya diseased patients with renal artery stenosis accounted for 1. 6%(15 / 927)of the total number of patients with moyamoya disease admitted in the same period. In the RAS group,the left renal artery stenosis accounted for 5 cases,the right renal artery stenosis accounted for 4 cases,and the bilateral renal artery stenosis accounted for 6 cases. Mild stenosis accounted for 71. 4%(15 / 21 sides), proximal stenosis accounted for 85. 7% (18 / 21 sides). The incidence of hypertension (80. 0%,n = 12) of the RAS group was significantly higher than that of the MMD group (30. 0%,n =9). There was significant difference (χ2 = 10. 045,P < 0. 05). There was significant difference in the distribution of Suzuki stage between the patients of the two groups (Z = -6. 184,P <0. 01). (2)Four patients underwent interventional therapy,their blood pressure decreased to normal level after procedure. Three patients were followed up for 9 months to 108 months with angiography after interventional treatment. No restenosis occurred in renal artery.
Conclusion The incidence of hypertension in patients with RAS is significantly higher than that without RAS,and there is difference between the degree of intracranial vascular lesions and the patients without RAS. Renal artery stenosis is mainly the proximal mild stenosis. Interventional therapy is an effective method for the treatment of moyamoya disease with severe renal artery stenosis;however,the long-term prognosis needs to be further followed up.
9.Bronchopulmonary Lophomonas blattarum infection: two cases report and literature review
Guozhong YAO ; Liqiang ZENG ; Bo ZHANG ; Zhengshan CHANG
Chinese Journal of Internal Medicine 2008;47(8):634-637
Objective To improve the recognition and diagnosis of pulmonary Lophomonas blattarum infection. Methods Two cases of bronchopulmonary Lophomonas blattanan diagnosed in this hospital were reported. The clinical features of 13 cases in the literature during the period of 1993 to 2006,1 case with sinus infection and 12 cases with bronchopulmonary infection, were also analyzed. Results For the 2 cases diagnosed in this hospital, severe asthma and bronchiectasis withprolonged infection were the underlying diseases, respectively. The diagnosis of these 2 cases and the 13 cases reported in the literature were all confirmed by the presence of parasites in airway samples. The most common symptoms included fever (64.3% ), cough and expectoration (71.4%). Fifty percent of the patients showed increased eosinophils in peripheral blood. Chest radiograph and CT scan showed changes similar to pneumonia(83.3%). Chronic cases were manifested with asthma attack, branchiectasis or lung abscess. Smear preparations of sputum or specimen by bronchoscopy were direct methods for diagnosis. Conclusion Pulmonary Lophonomas blattarum infection is an emerging infectious disease caused by protozoon of hypermastigote parasitized in the bronchus or the lung. Epidemiological characteristics including host, route of transmission and susceptible population of Lophomonas blattarum infection are not fully understood. The optimal treatment also needs further investigation.
10.Magnetic resonance imaging presentations of 26 patients with neurosyphilis
Chang ZHOU ; Demao DENG ; Chen ZHANG ; Yongfeng XU ; Zhengshan LIU ; Boning LUO ; Cheng ZHANG ; Quanfei MENG
Chinese Journal of Neurology 2008;41(2):93-96
Objective To analyses the magnetic resonance imaging(MRI)findings of different clinical patterns of neurosyphilis(NS).Methods Clinical records and MRI of 26 patients with NS were retrospectively studied.Results Abnormal MRI was found in 17 patients of 26 patients with NS.In 7 patients were with meningo-vascular syphilis,the MRI commonly showed multiple cerebral ischemia focus and cerebral infarction focus,very few similar to those of encephalitis;Six patients had general paresis,who presented cerebral MRI abnormalities of frontal and temporal atrophy,and few simultaneously with cerebral ischemia focus,granular apendymitis and hippocampus sclerosis;Three patients had syphilitic myelitis,their MRI showed mild tumefaction with multiple ischemic focus all the way through lower cervical spinal cord to lower thoracic spinal cord:One patient was with tabes dorsalis,whose cerebral MRI showed ischemic locus.Another 9 patients had normal MRI,of whom 4 patients with meningitis NS and 5 with tabes dorsalis.Conclusion The MRI of neurosyphilis has diverse presentations,and clinicians should pay much attention to it.