Objective To explore the application value of noninvasive positive pressure ventilation for acute left heart failure. Methods 86 patients with acute left heart failure were selected and randomly divided into study group and control group,43 patients in each group. Two groups of patients after diagnosis,the control group were treated with conventional treatment, while patients in the study group were given breathing machine with noninvasive positive pressure ventilation treatment. Results Compared with control group,the efficiency and total effective rate in the study group were significantly increased, but the ineffictive rate significantly lower, there were significant differences (P<0. 05). At the same time,patients in the study group,HR and RR were significantly decreased,while PaO2 and SaO2 treatment were significantly higher, there were significant differences (P < 0. 05). Conclusion Use of noninvasive positive pressure ventilation for acute left heart failure,its effects were positive,significant effect on the treatment of acute left heart failure is of great clinical value.