1.MORPHOMETRIC STUDY OF THE POSTERIOR COMMUNICATING ARTERY IN CEREBRAL ARTERIAL CIRCLE OF WILLIS
Acta Anatomica Sinica 1955;0(03):-
Objective\ The posterior communicating arteries (PCoA) are the most variable in the cerebral arterial circle of Willis. The figure of Chinese in Taiwan is required to be filled up in the category of Chinese stream. Methods\ In this study, the outer diameter of the PCoA was measured through an imaging computing system with enlargement up to twenty times for the collected fifty formalined adult human brains of Chinese in Taiwan. Results\ The external diameter of the internal carotid end of the PCoA averaged 1\^72?0\^77( ?s )(0\^7 4 3) mm in the left and 1\^69?0 78(0\^8 3\^3) mm in the right; 1\^59?0\^58(0\^8\|3\^0) mm in the left side of the posterior cerebral end and 1\^59?0\^68(0\^5\|3 2) mm in the right side of it. Conclusion\ These data display close to the white people values and are wider than that of Mainland Chinese. It is due to virtue in the usage of measurement.\;[
2.Study of syndrome differentiation factor of gouty arthritis with blood stasis syndrome based on connection number.
Bin LI ; Rong XU ; Fulun LI ; Keqin ZHAO ; Ming ZHANG ; Zhengcheng XU
Journal of Integrative Medicine 2009;7(8):724-8
To find the related syndrome factors of gouty arthritis with blood stasis syndrome by mathematical methods of set pair analysis and connection number so as to guide the diagnosis.
3.Qinzhu Liangxue Decoction in treatment of blood-heat type psoriasis vulgaris: a randomized controlled trial
Fulun LI ; Bin LI ; Rong XU ; Xun SONG ; Yang YU ; Zhengcheng XU
Journal of Integrative Medicine 2008;6(6):586-90
OBJECTIVE: To explore the clinical efficacy of Qinzhu Liangxue Decoction (QZLXD), a compound traditional Chinese herbal medicine, in patients with blood-heat type psoriasis vulgaris. METHODS: Fifty-eight patients diagnosed with blood-heat type psoriasis vulgaris were randomly divided into two groups: QZLXD group (30 cases) and ampeptide group (28 cases). Patients in both groups were treated for 4 weeks. Psoriasis Area and Severity Index (PASI) score, Dermatology Life Quality Index (DLQI) score and the level of serum vascular endothelial growth factor (VEGF) were obtained to evaluate the efficacy of the two treatments. RESULTS: There was a better curative result in QZLXD group than in ampeptide group (P<0.05). The response rates in QZLXD and ampeptide groups were 83.33% and 64.28% respectively. DLQI score was also significantly improved during 4-week treatment in QZLXD and ampeptide groups (P<0.05). There was no significant difference in VEGF level between QZLXD and ampeptide groups. CONCLUSION: QZLXD is remarkably advantageous in treatment of psoriasis vulgaris of blood-heat syndrome and improvement of patient's quality of life. The mechanism may be related to decrease in serum VEGF level and action against neogenesis of blood vessels.
4.Cardiovascular and Renal Damage in Hypertensives Complicated with Metabolic Disorders
Xingsen XU ; Wantao YANG ; Daoyan LIU ; Jian ZHONG ; Zhiqiang TIAN ; Zhengcheng YAN ; Yinxing NI ; Jing CHEN ; Zhigang ZHAO ; Zhiming ZHU
Chinese Journal of Hypertension 2006;0(11):-
Objective To study the target organ damage in patients of hypertension with metabolic disorder. Methods 1033 patients were divided into five groups: hypertension without complications(102 cases), hypertension with dyslipidemia (117 cases), hypertension with abdominal obesity(119 cases), hypertension with type 2 diabetes mellitus(135 cases), hypertension with metabolic syndrome (560 cases). The structure and the function of heart and blood vessel were examined by color Doppler. Urinary microalbuminuria was determined. Results (1)Only 9.9% patients of hypertension were without metabolic disorder, 90.1% hypertensives complicated with the metabolic disorder; (2)Compared with hypertension with dyslipidemia, hypertension with type 2 diabetes mellitus (P90%) complicated with the metabolic disturbance. Hypertension complicated with abdominal obesity accentuate left ventricular hypertrophy. Hypertension with diabetes mellitus and metabolic syndrome accentuated the vascular and renal lesion.
5.Construction of a nomogram model for predicting risk of spread through air space in sub-centimeter non-small cell lung cancer
Xiao WANG ; Yao ZHANG ; Kangle ZHU ; Yi ZHAO ; Jingwei SHI ; Qianqian XU ; Zhengcheng LIU
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2025;32(03):345-352
Objective To investigate the correlation between spread through air space (STAS) of sub-centimeter non-small cell lung cancer and clinical characteristics and radiological features, constructing a nomogram risk prediction model for STAS to provide a reference for the preoperative planning of sub-centimeter non-small cell lung cancer patients. Methods The data of patients with sub-centimeter non-small cell lung cancer who underwent surgical treatment in Nanjing Drum Tower Hospital from January 2022 to October 2023 were retrospectively collected. According to the pathological diagnosis of whether the tumor was accompanied with STAS, they were divided into a STAS positive group and a STAS negative group. The clinical and radiological data of the two groups were collected for univariate logistic regression analysis, and the variables with statistical differences were included in the multivariate analysis. Finally, independent risk factors for STAS were screened out and a nomogram model was constructed. The sensitivity and specificity were calculated based on the Youden index, and area under the curve (AUC), calibration plots and decision curve analysis (DCA) were used to evaluate the performance of the model. Results A total of 112 patients were collected, which included 17 patients in the STAS positive group, consisting of 11 males and 6 females, with a mean age of (59.0±10.3) years. The STAS negative group included 95 patients, with 30 males and 65 females, and a mean age of (56.8±10.3) years. Univariate logistic regression analysis showed that male, anti-GAGE7 antibody positive, mean CT value and spiculation were associated with the occurrence of STAS (P<0.05). Multivariate regression analysis showed that associations between STAS and male (OR=5.974, 95%CI 1.495 to 23.872), anti-GAGE7 antibody positive (OR=11.760, 95%CI 1.619 to 85.408) and mean CT value (OR=1.008, 95%CI 1.004 to 1.013) were still significant (P<0.05), while the association between STAS and spiculation was not significant anymore (P=0.438). Based on the above three independent predictors, a nomogram model of STAS in sub-centimeter non-small cell lung cancer was constructed. The AUC value of the model was 0.890, the sensitivity was 76.5%, and the specificity was 91.6%. The calibration curve was well fitted, suggesting that the model had a good prediction efficiency for STAS. The DCA plot showed that the model had a good clinically utility. Conclusion Male, anti-GAGE7 antibody positive and mean CT value are independent predictors of STAS positivity of sub-centimeter non-small cell lung cancer, and the nomogram model established in this study has a good predictive value and provides reference for preoperative planning of patients.