1.Analysis on the use of antibacterial drugs during preoperative period of cesarean sections
Chinese Journal of Health Policy 2014;(9):68-71
Objective:To investigate the use of antibacterial drugs during the perioperative period of a cesarean section and observe the differences before and after antibacterial drug remediation. Methods:1 569 cesarean cases from 2010 to 2012 were investigated, and the use of antibacterial drugs, drug categories, drug combinations, medical expenses, and so on was statistically analyzed with the use of the statistical software SPSS13. 0. Results:The rate of antibacterial drug usage within the 1 569 cesarean cases was 100%;for pre-operative antibacterial drug remediation, azithromycin, cefathiamidine, and ornidazole were the top three, while the top three antibacterial drugs for post-oper-ative remediation were arecefathiamidine, cefuroxime, and clindamycin. There was no significant difference between the two groups of incision infections, and the rate for combined use of drugs dropped. The analysis of drug costs is of statistical significance. Conclusion:The analysis of antibacterial drug remediation is useful for the rational use of anti-bacterial drugs and a reduction of costs.
2.Expression of Inducible Nitric Oxide Synthase and NF-κ Bp65 in Patients with Psoriasis Vulgaris and Their Clinical Significance
Chinese Journal of Dermatology 2001;34(2):103-104
Objective To investigate the internal relationship between the expression of inducible nitric oxide synthase (iNOS) and the activation of NF-κ Bp65 in the skin of patients with psoriasis vulgaris(PV) and their roles in the pathogenesis of PV.Methods The expression and distribution of iNOS and NF-κ Bp65 were studied by in situ hybridization and immunohistochemistry in 20 patients with PV and 12 healthy controls.The severity of PV was assessed by Psoriasis and Severity Index(PASI) score.Results ① The expression of both iNOS mRNA and protein was significantly higher in lesional epidermis than those in non-lesional epidermis and epidermis of the controls (P<0.01).Weak exprssion of iNOS mRNA was found in basal cell layer in a small number of healthy controls, however, strong expression was observed in entire basal cell layer and focal parts of prickle cell layer in all PV epidermis.② There was significantly positive correlation between iNOS and NF-κ Bp65 protein expression in lesional epidermis (P< 0.01).③ There was significantly positive correlation between the level of expression of iNOS mRNA in lesional epidermis and PASI score of patients (P< 0.01).Conclusions The expression of iNOS and NF-κ Bp65 is markedly increased in lesional epidermis of patient with PV.The activation of NF-κ B probably takes part in the pathogenesis of PV.High-level expression of iNOS may be due to the activation of NF-κ B.
3.Social Factors Analysis of the Absence of Professional Ethics among Accountants
Chinese Medical Ethics 1996;0(01):-
As the repeated emergence of accounting communication distortion and criminal behaviors among accounts,the absence of accounts′ professional ethics is drawing increasing attention from the general public.The professional ethics absence is partially related to the imperfect self-discipline of accountants.However,self-discipline by its own can never solve the absence of accounts′ professional ethics to some extent.Certain social factors are also responsible,which are analyzed in this thesis,aiming to provide a welcoming external environment for the improvement of professional ethics among accountants.
4.The clinical observation of three-dimensional conformal radiotherapy simultaneously combined with XELOX program for local recurrence of esophageal carcinoma after radiotherapy
Chinese Journal of Postgraduates of Medicine 2012;35(20):26-29
ObjectiveTo investigate the clinical effect of three-dimensional conformal radiotherapy simultaneously combined with XELOX program(oxaliplatin +capecitabine) for local recurrence of esophageal carcinoma after radiotherapy.MethodsSixty patients with local recurrence of esophageal carcinoma after radiotherapy were divided by random digits table method into treatment group and control group with 30 cases each.The patients in treatment group were treated with three-dimensional conformal radiotherapy simultaneously combined with XELOX program chemotherapy.While control group received three-dimensional conformal radiotherapy.The efficacy between two groups were compared.ResultsThe complete remission rate and efficiency rate in treatment group were significantly higher than those in control group [ 53.3% (16/30) vs.23.3% ( 7/30 ),86.7% ( 26/30 ) vs.63.3% (19/30) ] ( P < 0.05 ).The 1,2,3-year survival rate and median survival time in treatment group were 65.5%,44.8%,34.5% and 24.8 months,which were significantly higher than those in control group (48.3%,41.4%,6.9% and 12.1 months)(P <0.01 ).The incidences of radioactive esophagitis,radioactive pneumonia and thrombocytopenia in treatment group were higher than those in control group,but there were no statistical differences between two groups (P >0.05).The incidences of nausea,vomiting,leukocyte decrease and anemia in treatment group were significantly higher than those in control group [36.7%(11/30) vs.13.3%(4/30),40.0%(12/30) vs.16.7%(5/30),43.3%( 13/30 ) vs.13.3%(4/30),P < 0.05 ].ConclusionsThree-dimensional conformal radiotherapy simultaneously combined with XELOX program can improve short-term efficacy and long-term survival rate of local recurrence of esophageal carcinoma after radiotherapy.
5.Variability analysis of human cytomegalovirus
Chinese Journal of Laboratory Medicine 2003;0(07):-
Objective Comparing the variability of four genes of HCMV in the population and the therapy process of single patient.Methods Using PCR to amplify the four genes and restriction enzyme to validate four fragments, These four genes are UL55,UL57,UL86 and UL122 whose coding products are glycoprotein B,single chain binding protein,main capsid protein and IE pp86 separately. Then we use AD169 to optimize the conditions of PCR and restriction enzyme. then we use these conditions to detect 200 blood specimens. Results The PCR positive rate of UL55 is 12.5% and restriction positive rate is 10.0%, which has marked difference with other 3 gene segments(P
6.Factors affecting accumulation of hydrolysable tannins in cultured mycelia of Inonotus obliquus
Chinese Traditional and Herbal Drugs 1994;0(12):-
Objective To study the factors affecting the accumulation of hydrolysable tannins in cultured mycelia of Inonotus obliquus. Methods Taking dry weight of mycelia and hydrolysable tannin content as index, different carbon and nitrogen sources, pH levels, and metal ions were evaluated for the accumulation of hydrolysable tannins in the submerged culture of I. obliquus. Results The optimal carbon and nitrogen sources were glucose and peptone. Optimal initial pH value was 5.5. The accumulation of hydrolysable tannins was greatly enhanced in the medium with the presence of Cu2+ at 0.8 mmol/L, Co2+ and Zn2+ at 1.6 mmol/L, Mn2+ at 1 mmol/L, and NH4+ at 4 mmol/L when compared to the control. Conclusion The accumulation of hydrolysable tannins is maximized in the medium containing glucose and peptone with pH value at 5.5. Supplementation of Cu2+, Co2+, Zn2+, and Mn2+ into the medium is an effective method for further increasing the accumulation of hydrolysable tannins in cultured mycelia of I. obliquus.
7.THE DISTRIBUTION OF LYSINE,METHIONINE,VALINE AND THREONINE IN WHOLE RICE GRAIN IN RELATION TO THE DEGREE OF MILLING IN MODERATION
Acta Nutrimenta Sinica 1956;0(01):-
Whole rice grain was dissected by hand into fractions of pericarp, ale-urone, scutellum, embryo and endosperm. For the convenience of having enough amount of samples for amino acids assay some of which were recom-bined and finally three parts, pericarp +aleurone layer, scutellum + embryo and endosperm, were obtained. Protein, lysine, methionine, threonine and valine contents were determined for each part. The data obtained indicated that although total weight of the first two parts accounted for only 7.27-8.43% of the whole grain, they contributed 14.5-15.8% protein, 29.0-30.5% lysine, 11.8% melhionine, 16.8% valine and 19.4% threonine, contained in the whole grain. During husking process it indicated that the lesser amounts of pericarp, aleurone, scutellum and embryo were retained and the larger percentage of protein and lysine was lost. This fact was identified either by a specially designed miller in the laboratory or a commonly used sand wheel miller in the factory. The suitable degree of milling for rice was discussed and it was proposed that 92% extration for rice rather rational.
8.LYSINE AND METHIONINE CONTENTS IN PROTEINS OF RICE VARIETIES GROWN IN DIFFERENT PROVINCES
Acta Nutrimenta Sinica 1956;0(02):-
Lysine and methionine contents were determined in proteins of 21 rice samples including 17 varieties grown in 11 provinces. Ranges of lysine and methionine contents on crude protein basis were 3.21-3.76% and 1.63-2.06% respectively. The lysine content was found to be negatively correlated with the protein content of rice, but no correlation was found in case of methionine when they were expressed on the basis of crude protein. The absolute amounts of lysine and methionine were positively correlated with protein contained in the samples. The importance of breeding rice variety with protein of high lysine content was discussed in relation to promoting the protein nutritive status in South China.
9.SULFUR AMINO ACIDS CONTENT IN PROTEINS OF CEREALS, BEANS, FISHES AS WELL AS MEATS
Acta Nutrimenta Sinica 1956;0(03):-
A convenient microbiological method with high accuracy for cystine assay was introduced. Common foods including cereals, beans, sweet potato, fishes and other aquatic products as well as meats were selected for cystine and methionine analysis. Based on the data obtained, a brief discussion was made on the way for resolution of sulfur amino acids problem inherently in our traditional soy-cereal based diet.
10.Activity and Localization of ?-GT, ANAE, AKP and G-6-P in the Epididymis of the Rat
Journal of Third Military Medical University 1984;0(02):-
Activity and localization of y-glutamyl transpeptidase (?-GT) , ?-Naph-thyl acetate esterase (ANAE) , alkaline phospbatase (AKP) and glucose-6-phosphatase (G-6-P) in the epididymis of the rat has been investigated histo-chemically by light microscopy.?-GT activity was mainly localized on the supranuclear region and the ste-reocilia of the epithelial cells. The intensity in the epithelium of the segment Ⅱ is the highest of the rat epididymis. There was a gradual decrease in the intensity of this enzyme from segment Ⅲ through Ⅳ and it was absent from the segment Ⅳ. Activity of ANAE in the segment Ⅳ, Ⅴ and Ⅵ was higher, but that in the segment Ⅰ,Ⅱ and Ⅳ was less. ANAE activity was localized throughout the cytoplasm of the epithelial cells in the segment Ⅰ,Ⅲ, Ⅴ and Ⅵ. Whereas the activity in the segment Ⅱ and Ⅳ was localized on the basal region of the epithelial cells. AKP activity was present in the basement membrane of the epididymal epithelium and the bloodvessel wall of subepithelial connective, tissue of the epididymal duct. G-6-P was distributed homogenously in the cytoplasm of the epithelial cells throughout the epididymal duct.The possible function of these enzymes in the rat epididymis are briefly discussed.