Colorectal Neoplasms ; diagnosis ; prevention & control ; Humans ; Translational Medical Research

AIM: To study the expression level of gene SNC66 in gastric cancer tissues, and investigate the relationship between the expression of SNC66 and the pathogenesis of gastric cancer.METHODS: Paired normal and cancerous paraffin-embeded tissues from 20 gastric cancer patients were tested by in situ hybridization (ISH) and in situ reverse transcription and polymerase chain reaction (ISRT-PCR)using ?-actin as a control.RESULTS: ISH and ISRT-PCR both showed that SNC66 were all strong positive expressed in 20 normal gastric mucosa.But in 20 gastric cancer tissues,the ISH showed that 8 were negative,8 were weak positive and 4 were strong positive. The ISRT-PCR showed that 6 were negative,9 were weak positive and 5 were strong positive when the PCR cycled 10 times;4 were negative and 16 were strong positive when the PCR cycled 25 times. CONCLUSION: There was significant expression reduction or defect of SNC66 in gastric cancer tissues.SNC66 should be further investigated as a gastric cancer negative relative gene.

Angioplasty, Balloon, Coronary ; Chronic Disease ; Coronary Disease ; therapy ; Coronary Occlusion ; therapy ; Humans

Child, Preschool ; Dental Restoration, Permanent ; Dentition, Permanent ; Humans ; Infant ; Root Canal Therapy ; Tooth Avulsion ; therapy ; Tooth Crown ; injuries ; Tooth Extraction ; Tooth Fractures ; therapy ; Tooth Injuries ; therapy ; Tooth, Deciduous ; injuries ; Tooth, Impacted ; etiology

Humans ; Liver Transplantation ; standards ; trends

Child ; Dental Restoration, Permanent ; Dentition, Permanent ; Humans ; Incisor ; diagnostic imaging ; injuries ; Male ; Orthodontic Appliances ; Orthodontic Extrusion ; Orthodontics, Corrective ; Radiography ; Tooth Avulsion ; classification ; diagnostic imaging ; therapy ; Tooth Eruption

0.05). Conclusions The detections of survivin and MCM5 in urine sediments are sensitive and non-invasive diagnostic tests for bladder cancer.The combination of survivin and MCM5 may be more effective than either of them alone.

Biliary Tract Diseases ; etiology ; prevention & control ; therapy ; Cholestasis ; etiology ; prevention & control ; therapy ; Humans ; Liver Transplantation ; adverse effects

Child ; Humans ; Incisor ; abnormalities ; Maxilla ; Occlusal Adjustment ; Orthodontic Extrusion ; Tooth Abnormalities ; diagnosis ; etiology ; therapy ; Tooth, Impacted ; diagnosis ; etiology ; therapy

Child ; Humans ; Molar ; Orthodontic Wires ; Radiography, Panoramic ; Tooth Eruption, Ectopic ; diagnostic imaging ; pathology ; therapy