5.Restrospective Analysis of Linezolid and Teicoplanin in the Treatment of Elderly Patients with Severe MRSA Infection
China Pharmacy 2015;(29):4140-4142
OBJECTIVE:To investigate therapeutic efficacy and safety of linezolid and teicoplanin in the elderly patients with severe MRSA infection. METHODS:97 elderly patients with severe MRSA infection were collected and divided into linezolid group (42 patients) and teicoplanin group (55 patients). Linezolid group was given linezolid 600 mg intravenously,bid;teico-planin group was given teicoplanin 400 mg intravenously,qd,double dose for the first day. Treatment course lasted for 7-21 d. Clin-ical effective rate,bacterium clearance rate and ADR were compared between 2 groups after treatment. RESULTS:The bacterium clearance rate of teicoplanin group was 52.6%,and that of linezolid group was 73.5%;the linezolid group was significantly higher than the teicoplanin group,with statistical significance(χ2=12.57,P=0.034). Clinical effective rate was 78.6% in linezolid group and 58.2% in teicoplanin group;the linezolid group was significantly higher than the teicoplanin group,with statistical significance (χ2=9.56,P=0.018). After 14 days of treatment,APACHEⅡ score of teicoplanin group and linezolid group were (14.56±3.04) and(10.29±4.84),respectively;the teicoplanin group was lower than the linezolid group,with statistical significance(t=10.97, P=0.014). The incidence of ADR was 11.9% in linezolid group and 20.0% in teicoplanin group,with statistical significance(χ2=1.13,P=0.287). CONCLUSIONS:Linezolid has superior curative effect to teicoplanin in the treatment of severe MRSA infection in elderly patients with good safety.
6.The features of oral and maxillofacial surgery in China and the challenges we are facing.
Chinese Journal of Stomatology 2011;46(4):193-196
China
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Cleft Lip
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epidemiology
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Cleft Palate
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epidemiology
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Dentist-Patient Relations
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Health Services Needs and Demand
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History, 20th Century
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History, Ancient
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History, Medieval
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Humans
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Malocclusion
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epidemiology
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Mouth Neoplasms
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epidemiology
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Prevalence
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Surgery, Oral
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education
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history
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organization & administration
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trends
7.Quantitative analysis of different files in full-text papers published in biomedical journals
Zhen GUO ; Hongyu KANG ; Zhen HOU ; Jiao LI
Chinese Journal of Medical Library and Information Science 2017;26(3):32-36
The variability and number of appendixes, publication year and publication journals of full-text files conforming to the JATS standards, selected from 891334 full-text papers published in biomedical journals, were analyzed, which showed that the number of non-text files increased sharply with their appendixes reached 45, and jpg, png, tif accounted for 81%.
Result Analysis
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