1.Curative effect of calcium hydroxide paste combined with root canal in treatment of pulpitis and apicitis
Chinese Journal of Biochemical Pharmaceutics 2016;36(6):79-81
Objective To investigate the clinical curative effect of calcium hydroxide paste combined with root canal in treatment of pulpitis and apicitis.Methods A total of 76 patients with pulpitis and apicitis from Dec.2014 to Aug.2015 were collected and randomly divided into two groups, 38 cases in each group.Control group (65 tooth ) were treated by routine root canal therapy, with zinc oxide iodoform clove oil cement filling root canal;experimental group (71 tooth) were treated by routine root canal therapy, with calcium hydroxide paste filling root canal.Periodontal index, pain during root canal therapy ( IAE ) , serum inflammatory factors and clinical curative effect were observed and compared between two groups pre-and post-treatment.Results Compared with pre-treatment, periodontal index of PLI, BI, PD and GI in two groups were all lower (P<0.05), and IL-6, IL-8, IL-1βand TNF-αwere lower(P<0.05).Compared with control group, PLI, BI, PD and GI of experimental group were lower (P<0.05), IL-6, IL-8, IL-1βand TNF-αwere lower(P<0.05),too.The difference of IAE incidence between two groups was significant (P<0.01) and the clinical curative effect of experimental group was 88.73%, higher than 72.31% of control group (P<0.05).Conclusion Calcium hydroxide paste combine with root canal therapy in treatment of pulpitis and apicitis are effective, which can significantly improve periodontal condition of tooth, reduce the occurrence of pain during root canal therapy.
2.Build Staff Performance Evaluation System of Medical Research Institutes
Youqin HE ; Jingliang GU ; Tianmin ZHEN
Chinese Journal of Medical Science Research Management 2016;29(3):209-212
Objective To establish staff performance evaluation system of academy of medical sciences.Methods The Delphi method was employed.Results The main indicators of staff performance evaluation were selected by two-round of the Delphi method,and the evaluation system was established.Evaluation indicators covered different types of jobs of science research,medical services,disease prevention,medical education,science and technology support.Conclusions After two-round of consultation,there were more consistencies among experts regarding to selection of evaluation indicators.It will be tested and justified by further theoretical and empirical research.
3.Air Pollution on Activity of Aryl Hydrocarbon Hydroxylase in Placenta Tissue of Women in Taiyuan
Heng GU ; Yinlong JIN ; Zhen XU
Journal of Environment and Health 2007;0(11):-
Objective To know the effects of air pollution on the activity of aryl hydrocarbon hydroxylase (AHH) in the placenta tissue of women in Taiyuan, Shanxi Province. Methods The decrement of BaP after the metabolic procedure was used as the indicator of AHH activity. 151 lying-in women were selected and the AHH activity in the placenta was determined by fluorescence spectrophotometer, the precooling EDTA was added in the determination to inactivate AHH and to stop the reaction completely in order to get more stable result. Results The AHH activity in the placenta tissue increased as the atmospheric particle concentration and the BaP concentration in the particles increased. Conclusion The air pollution may induce the AHH activity increase in the placenta tissue of pregnant women in Taiyuan. The AHH activity can be used as the biological monitoring indicator in the PAHs polluted areas.
4.Serum levels and clinical significance of IL in patients with delayed encephalopathy after acute carbon monoxide poisoning.
Long ZHEN ; Ren-jun GU ; Ping ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(9):561-562
Adult
;
Aged
;
Aged, 80 and over
;
Carbon Monoxide Poisoning
;
complications
;
Female
;
Humans
;
Interleukins
;
blood
;
Male
;
Middle Aged
;
Neurotoxicity Syndromes
;
blood
;
etiology
5.Diagnostic analysis of different index in adult onset Still's disease
Zhen WANG ; Lindi JIANG ; Jie GU
Chinese Journal of Rheumatology 2010;14(3):192-194
Objective To evaluate the value of clinical findings and different diagnostic criteria for the diagnosis of adult onset Still's disease (AOSD). Methods The AOSD patients admitted to Zhongshan Hospital affiliated to Fudan University from 2003 to 2009 were enrolled. Non-AOSD patients with fever were selected. Different diagnostic criteria of AOSD were applied to all patients. Two indenpendent samples t test and wilco-xon test were used for statistical analysis. Results The clinical features such as rash, arthralgia, arthroncus, sore throat, myalgia, lymph node enlargement, hepatomegaly, splenomegaly, leuko-cytosis, neutrophil ≥80% and serum level of ferrin≥ 2000 ng/ml hadhigher specificity (65.87%~98.41%) with 2.00~5.00 of the positive likelihood ratio.High fever ( ≥39.0℃), negative of ANA and RF had higher sensi-tivity (85.25%~93.65%). Combinations of three parameters such as high fever, rash, sore throat, leukocy-tosis, arthralgia had higher positive likelihood ratio. The specificity of ARA criteria was the highest. The sensitivity and accuracy of Yamaguchi criteria were the highest. Conclusion There is no single parameter that could be specific to the identification of AOSD. Combing with several parameters can improve the diagnostic efficiency. The results of this study have shown that the commonly used diagnostic criteria has high specificity.
7.Clinical study of low dose continuous infusion of ceftazidime (CAZ)forthe treatment of low respiratory tract infections
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(03):-
0.05). Conclusions Low dose continuous infusion of CAZ to treat low respiratory infections is efficacious ,safe and economical.
8.Application of patients with specific behaviors in the facial trauma clinical teaching
Zhen YANG ; Fazhi QI ; Jianying GU
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(11):1029-1030
Objective To detect the feasibility of patients with specific behaviors in the facial trauma clinical teaching. Method 47 medical students were randomly divided into experimental group ( n = 22 ) and control group(n=25). Students from experimental group at least dealed with 5 ~ 10 facial trauma patients with specific behaviors, while specific behaviors patients in control group were not more than 2. Teaching results were compared. Results There was no significant difference in operation test scores between the two groups ( (84.68 ±3.41 ) vs ( 83.96 ± 3.46 ), P = 0. 476 ). Composite score of teachers in the experimental group was significantly higher than that in control group( (90.09 ± 5.69 ) vs (83.48 ± 5.19), P < 0.01 ). The results of questionnaire survey showed that two in five self-assessment results were higher in the experimental group(P < 0. 01 ). Conclusion Medical students are more appropriately involved in treating special behaviors patients, which can improve the overall quality of students. Teaching with special behaviors patients has good effect, and is feasible.
9.Research on the Construction and Development Strategy of Electronic Medical Records---taking the development state of hos-pitals Electronic Medical Records in Shandong province as an example
Xueshu XIE ; Tianmin ZHEN ; Jingliang GU ; Weili ZHAO
Journal of Medical Informatics 2015;(6):13-17
〔Abstract〕 Based on investigating construction and utilization status of hospital Electronic Medical Records ( EMR ) in Shandong province, the paper understands the current development status of EMR in various level hospitals in Shandong province.In view of the problems it puts forward some countermeasures and suggestions, so as to provide references for promoting the development of EMR of the hospitals at all levels scientifically, optimizing the allocation of health resources.
10.Monitoring low-risk death cases through Beijing-diagnosis related groups for improvement of the medical ;quality
Wenfeng WANG ; Jing CHEN ; Wanying LIU ; Shui GU ; Zhen WANG
Chinese Journal of Hospital Administration 2015;(7):520-523
Objective To explore methods of quickly identifying loopholes in medical quality management and to improve medical quality by means of analyzing low-risk death cases.Methods Two rounds of analysis of 1 14 low-risk death cases of hospitals in Beijing in 2012 in terms of data quality and medical procedures,in an effort to identify problems and to verify the feasibility and accuracy of the method through interaction with other data.Results Totally 585 760 inpatients were discharged in 2012 from 21 hospitals,of whom 1 5 1 1 93 being low-risk cases.Such cases included 1 14 low-risk death cases, accounting for 0.01 9% of the total discharged,and 0.075% of low-risk discharged cases.Analysis of these medical records found 50 cases of problematic diagnosis (43.86%),45 cases of possible defects in diagnosis and treatment (39.47%),39 cases of missing items of secondary diagnosis (34.21%),and 28 cases of missing items of surgery/operation (24.56%). Some of the abovementioned cases had overlapping mistakes.Conclusion Analysis of low-risk death cases can help focus among massive data of medical records,problems of diagnostic and therapeutic insufficiency,pinpointing common problems in medical service and improving medical quality and fine management of hospitals.