Objective Study the effect of Shuxuetong combined with Shenmai injection on serum CPR, SOD and MDA levels in elderly patients with acute myocardial infarction after PCI, and to analyze the main adverse cardiovascular events. Methods Chose 88 patients with PCI from June 2015 to June 2016 in our hospital, they were randomly divided into observation group and control group, 44 cases in each group. The control group was given conventional drug therapy before PCI. On the basis of this, the observation group was treated with Shuxuetong combined with Shenmai intravenous injection before PCI. The treatment of the two groups continued to one week after PCI. Compared the levels of serum malondialdehyde (MDA), superoxide dismutase (SOD) and hypersensitive C-reactive protein (hs-CRP) between the two groups before and after PCI, and compared the levels of coagulation factor, dynamic electrocardiogram, Left ventricular ejection fraction (LVEF) and myocardial infarct size, and compared the incidence of arrhythmia and major adverse cardiovascular events after PCI. Results The levels of serum MDA and hs-CRP in the observation group were significantly lower than those in the control group (P<0.05), the level of SOD was significantly higher than the control group (P<0.05); The level of coagulation factor in the observation group was significantly higher than that in the control group (P<0.05). The myocardial infarct size, the number of ischemic attacks, the decrease of ST segment and the descending time of ST segment were significantly lower than those of the control group (P<0.01). The incidence of MACE was significantly lower in the observation group than in the control group (P<0.05). Conclusion Conventional treatment combined with Shuxuetong combined with Shenmai injection can effectively prevent ischemia-reperfusion injury in elderly patients with AMI, improve cardiac function and reduce the main adverse cardiovascular events after PCI, which reflects the combination of traditional Chinese and western medicine Advantages, worthy of clinical use.

Virtual reality is a technology to simulate the real world by computer, with 3 characteristics of immersion, interaction and imagination. It is a new method applied to gait rehabilitation after stroke. This article briefly introduced the characteristics of virtual reality, and the value for rehabilitation in stroke patients. The recent development of the studies on virtual reality in gait rehabilitation for stroke was summarized, mainly included the advantages of virtual reality technology, virtual reality hardware devices applied to the gait rehabilitation, and its therapeutic effect.

The expression of tissue factor (TF) on the surface can be called TF positive MP, which participate not only in thrombosis, but also in the invasion and metastasis of tumors. Therefore, this article will review the role of TF positive MP in patients with malignant tumors.

Objective To analyse the detective rate and significance in diagnosis of cerebral and meningeal metastases by MR.Methods 115 cases with cerebral and meningeal metastasis were proved by operation and pathology.There were male 86 and females 29 ranged in age from 17-77 years old,plain MR scan and enhanced MR scan were performed in all cases.Results In this group included 46 cerebral metastases(40.0%),33 meningeal metastasis(28.7%),36 both cerebral and meningeal metastases(31.3%). Different degree of enhancement was showed on enhanced MRI in all cases, "mouse tail signs"or"target signs" were appeared in which cerebral metastasis with the adjoining meninges involved.Conclusion MRI is a good method for diagnosing cerebral and meningeal metastasis.Enhanced MRI has an important value.

Objective To select the optimum conditions of Echinococcosis ELISA kit and kit preparation by using orthogonal experiments,then to test their detection performance.Methods Taking the absorbance of the samples as the indicator,orthogonal experiments of three factors four levels were taken to optimize the conditions of hydatid disease detection ELISA kit.Through L16 (43)orthogonal experiments,the concentration of the antigen(A),the dilution multiple of the sample (B) and the dilution multiple of the enzyme labeled antigen (C) were studied.The specimen were provided by The First Affiliated Hospital of Xinjiang Medical University specimen library collected between March 2011 and June 2013,including 36 sera confirmed alveolar Echinococcus by the gold standard,56 sera confirmed Echinococcus granulosus disease by the gold standard and 72 sera as the control group(including healthy people,cirrhosis,hepatitis,etc).Detecting sensitivity and specificity were compared using F test for statistical analysis.Results Orthogonal design showed the size proportion of three factors of echinococcosis ELISA kit:antibody dilution ＞ sample dilution ＞ antigen coating concentration.The optimal preparation conditions were A1 B2 C4,that was,the concentration of antigen was 1 mg/L,sample dilution of 1∶ 100,dilution of secondary antibody of 1∶160 000.Through the 3-factor and 4-level orthogonal design using F-test analysis,the fact of the concentration of the kit antigen(A),F =1.181,P =0.393; the fact of the dilution multiple of the sample (B),F =2.544,P =0.152,the fact of enzyme labeled antigen dilution (C) F =2.544,P =0.039.The sensitivity of the kit to Echinococcus granulosus disease and alveolar Echinococcus were 83％ (30/36),and 91％ (51/56),respectively; the specificity was 91％ (29/32) and 83％ (33/40); the misdiagnosis rate of 17％ (6/36) and 9％ (5/56) ; the misdiagnosis rate 9％ (3/32) and 18％ (7/40) ; positive likelihood ratio 8.86％ (83/9) and 5.20％ (91/18) ; negative likelihood ratio of 0.18％ (17/91) and 0.11％ (9/83).Conclusion Orthogonal design is a good method that can find out optimal conditions of preparation for Echinococcosis ELISA kit and improve the test performance.

Objective To analyse the MRI appearances of giant cell tumors of the bone and the relationship with their pathologic bases.Methods Histologic examinations were conducted in 21 cases,and their correlations with the MRI appearances were further evaluated.Results There were 3 cases of the Ⅰ grade,3 cases of the Ⅰ～Ⅱ grade,13 cases of the Ⅱ grade,2 cases of the Ⅲ grade of the giant cell tumors.Most tumors were composed of solid content that presented sligthly low to intermediate signal intensity on T 1WI,sligthly high to high signal intensity on T 2WI.The minority of the tumors were composed of the half of the solid and cystic contents expectively.Specific tumors was mainly composed of cystic content or combined with fluid-fluid level on T 2WI.Soft tissue masses were found in 8 cases.Conclusion The location and their extension into the soft tissue of the tumors can be clearly demonstrated on MR imaging,but there is no relationship between the grades of the tumors and their MRI appearances.

Objective To evaluate the clinical value of rotational digital subtraction angiography(DSA).Methods The rotational DSA was performed 48 cases in 30 patients with PHILIPS V5000 digital imaging system.Among them,cerebral(n=8),carotid(n=2),limbs(n=7),hepatic(n=2),pulmonary(n=1),iliac(n=2),aortic(n=1),renal(n=2)and uterine(n=5)arteries were included.Results The origins,running,distributions,numbers and contours of diseased segments of arteries and pseudoaneurysm were clearly displayed in 28 of 30 patients with the technique of RDSA.Conclusion The RDSA is very useful in the preoperative diagnosis and selection of treatment for the diseased arteries.

0.05). The median duration of survival was 11.5 months for TEP gr oup versus 8.5 months for EP group (P0.05,no statistical difference). The main toxicity wa s myelosuppression for the two groups.The incidence rate of Ⅲ～Ⅳ degree neutro p enia and thrombocytopenia was higher in the TEP group than that in the EP group( P

Objective It has been known that NSAIDs can inhibit the growth of tumors through cyclooxygenase, but it is unknown that whether there are other mechanisms involved. It is essential to detect the effect of indomethacin for proliferation and apoptosis in the HCT116 and explore its anti tumor mechanism. Methods Human colon adenocarcinoma cell line HCT116 was treated with different concentration of indomethacin for 24 h and CDK 2,CDK 4, Bcl 2, Bax and p21 WAF1/CIP1 protein were detected by Western blot. Results Indomethacin down regulated the expression of CDK 2, CDK 4, Bcl 2 and up regulated the expression of p21 WAF1/CIP1 , however, the expression of Bax remained unchanged. Conclusions Inhibiting proliferation and inducing apoptosis contribute to the anti tumor activity of indomethacin by down regulating the expression of CDK 2, CDK 4, Bcl 2 and up regulating the expression of p21 WAF1/CIP1 .

Objective To determine the relation between the expression of urocortin and corticotropin-releasing hormone receptor 2? (CRH-R2?) in the placenta and pathogenesis of preeclampsia. Methods Placentas were collected from 20 pregnant women with preeclampsia as study group and 20 normal pregnant women as control group. Urocortin mRNA and CRH-R2? mRNA were measured by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR). Urocortin peptide was measured by immunohistochemistry. Results (1) The mRNA expression of urocortin was significantly higher (P