1.Summary of the experiment study on Angelica Decoction for Replenishing Blood
Zhaosheng HUANG ; Jianan WEI ; Zongwei WANG
Chinese Traditional Patent Medicine 1992;0(09):-
Having referred the Chinese academic publications on TCM during the last decade ,we summarized the researches in Angelica Decoction (AD), which included immunoregulatory, circulatory system, the basis of decoction composition, anti-oxidation, liver injury and compaibility. AD can improve the immunity action, meliorate abnormal circulation, and also has the effects of anti-oxidation and protection of liver injury. Futher study on AD should be focused on its mechanism and material basis in the future.
2.Effect of Combination of Rhizoma Coptidis and Fructus Evodiae in Various Proportions on Rat Models with Heat Syndrome Induced by Radix Codonopsis Pilosulae and Radix Astragali seu Hedysari
Shengqing LI ; Zhaosheng HUANG ; Yaoquan HUANG ; Pingqing WEI
Journal of Guangzhou University of Traditional Chinese Medicine 2001;0(01):-
[Objective] To observe the effect of combination of Rhizoma Coptidis (RC) and Fructus Evodiae (FE) in various proportions on rat models with heat syndrome. [Methods] Rat models with heat syndrome were set up by gastric infusion of Radix Codonopsis Pilosulae and Radix Astragali seu Hedysari. Fifty rats were allocated to five groups: normal control group (Group A), model group (Group B), model rats treated with RC and FE at the proportion of 6∶1 (Group C), model rats treated with RC and FE at the proportion of 2∶1 (Group D) and model rats treated with RC and FE at the proportion of 1∶1 (Group E). [Results] Ultrastructure of hepatic cells were improved in Group C, Group D and Group E. Indexes of heat syndrome such as temperature, serum corticosteroid (Cor) level and 17 - hydroxycorticosteroid (17-OHCS) content in homogenate of adrenal glands were decreased in Group C and Group D but stayed unchanged in Group E as compared with Group B ( P
3.The Pathological Study on Effective Compounds of TongMai in Treating MsPGN in Rats
Mingping LIU ; Zhaosheng HUANG ; Nizhi YANG ; Pingqing WEI ; Qingguang WU
Chinese Journal of Experimental Traditional Medical Formulae 2009;(7):54-57
Objective: To observe the therapeutic effects of effective compounds which were extracted from TongMai. Methods: SD rats experimential model with MsPGN were induced by subcutaneously injection rabbit anti-rat thymocyte serum(ATS) and forced swim. The rats were respectively ig with different dose(1.2,0.6,0.3 g'kg-1) of effective compound of TongMai for 4 weeks. Then the proliferative degree of mesangium was examined by HE stain, PAS stain and immunfluorescent respectively. Mesagium area proportion in glomerular capillaries area was calculated using image analyzing system. The expression of PCNA in the glomeruli was examined by immunohis to chemistry. Results: The effective compounds of TongMai can control the hyperplasia of the glomemlar mesangial cells (GMG)and the mainifold of the mesangial matrix, and prevent the deposit of IgG in mesangium. The proportions in glomerular capillaries area in model control group were significantly higher than that in the treatment groups; The express of proliferative cell nuclear antigen (PCNA) were ascended either. Conclusion: The effective compound of TongMai can improve the damage s of pathology in glomerular.
4.Effect on proliferation of glomerular mesangial cell by the dose compatible proportion between Radix Astrsgali and Radix Notoginseng in Tongmai Oral Liquid
Mingping LIU ; Zhaosheng HUANG ; Qingguang WU ; Pinqing WEI
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(03):-
Objective To study the effect on proliferation of glomerular mesangial(GMC) cell by the dose compatible proportion between Radix Astrsgali and Radix Notoginseng in Tongmai Oral Liquid(TMOL) so as to select the optimal dose proportion.Methods We used serological pharmacological methods to prepare Decoction of Tongmai of different dose proportions and assay its effect on the proliferation of GMC to confirm the best dose compatible proportion between Radix Astrsgali and Radix Notoginseng of Decoction of Tongmai.Results Both TMOL and the different proportions between Radix Astrsgali and Radix Notoginseng(6∶1,3∶1,1.5∶1) of Decoction of Tongmai could inhibit the proliferation of GMC cultured either in fetal cow serum(FCS) or in FCS plus lipoplysaccharide.The inhibitory effect of Decoction of Tongmai(3∶1) group was better than both Decoction of Tongmai 6∶1 and Decoction of Tongmai 1.5∶1.Conclusion The dose compatible proportion between Radix Astrsgali and Radix Notoginseng in TMOL was reasonable.
5.Investigation and Analysis on the Status Quo of Current Nurse -Patient Relationship in Guangzhou
Xiaohong BI ; Pusheng ZHENG ; Jie LIU ; Zhaosheng WEI ; Yunan HUANG
Chinese Medical Ethics 1995;0(02):-
An investigation of the current nurse-patient relationship is conducted in Guangzhou city,by analyzing the data it can be concluded that the attitude of nursing service and skills of communication,the degree of nurses' knowledge on their patients' cases have a significant influence on the nurse-patient relationship.Nurses should play a leading role in nurse-patient relationship.There is a lack of mutual consideration and understanding between nurses and patients,which lead to nurse-patient misunderstanding and conflicts.There is a strong desire to discuss the case together intensively between nurses and patients.Furthermore,the lack of effective communication and teamwork between medical staff will also hinder the relief of tension in current physician-patient relationship.
6.Comparative Studies on the Anti- inflammatory and Analgesic Actions of Huang qi Guizhi Wuwu Decoction and Its Compositions
Zhaosheng HUANG ; Xuguang SHI ; Wei ZHU ; Zhendong ZHAO ; Zhongwei WANG ;
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(02):-
Objective To investigate the anti- inflammatory and analgesic a ctions of Huangqi Guizhi Wuwu Decoction (HGWD) and its compositions and to study its rule of compatibility.Methods Analgesic action of HGWD and its compositio ns were observed by hot- plate method and acetic- acid- induced body twist me thod. Anti- inflammatory action of HGWD and its compositions were observed on t he models of xylene- induced auricular swelling in mice, celiac capillary perme ability in mice, cotton- induced granuloma in rats, albumem- induced arthritis and adjuvant arthritis in rats.Results HGWD and its drug pairs could inhibit the acute inflammation induced by albumen and xylene and rat adjuvant arthriti, decrease the celiac capillary permeability, inhibit the proliferation of granu loma, increase the pain threshold in mice and reduce the frequencies of body tw ist induced by acetic acid.Conclusion HGWD has significant anti- inflammatory and analgesic actions, so does single drug; Radix Astragali alone, but when Ra dix Astragali is used with the other drugs in HGWD, its effect can be enhanced.
7.The study on organ weights, blood physiological and biochemical parameters and immune cells in Rag2 knockout mice
Yu WANG ; Xuying WU ; Zhaosheng WEI ; Jinfeng WU ; Huizhen LIU ; Yushu TIAN ; Wenming ZHANG ; Zhiwei YANG
Chinese Journal of Comparative Medicine 2014;(5):56-61
Objective To measure the organ weights , blood physiological and biochemical parameters , and immune function of Specific Pathogen Free ( SPF) Rag2 knockout ( KO) mice.Methods Rag2 knockout mice were selected at five and ten weeks , and the organ weights , blood physiological and biochemical parameters were observed .The percentages of CD3+, CD4+, CD8+, CD19+, B220+, NK1.1+, and CD11b+were checked by FCM in Rag2 KO mice at six week of age in terms of its T , B lymphocyte function and NK cell activity .Results Among the same sex group of NOD/SCID mice, the weights of brain, lung, spleen, liver, heart, kidney, and the levels of TBIL, WBC in 10 weeks of age are higher than 5 weeks.At the same age, the weights of heart, kidney, liver, spleen, and the levels of AST, ALP, A/G, GLU, PLT, PCT, WBC, and LYM%in male mice are higher than females.The Rag2 KO mice lacks T cells(0.36 ±0.15)%、CD4+T cells(0.21 ±0.06)%、CD8+T cells(0.23 ±0.07)%、CD19+B cells(0.28 ±0.04)%、B220+B cells(2.03 ±0.42)%).The percentage of NK cells is(24.13 ±3.62)%, and the percentage of granulocytes is (57.20 ±3.85)%.Conclusion The study suggests that the organ weights , blood physiological and biochemical parameters are affected by age and gender in Rag2 KO mice, which main biological characteristics are similar with C 57BL/6J mice.The Rag2 KO mice show the deficiency of T , B cells function .
8.Development of automatic temperature and thermal current detection system for physiological protection equipment of the aviator
Qiong WANG ; Junqin LI ; Zhaosheng REN ; Wei LI ; Liyong SHI ; Lihao XUE ; Yanghua OU
Chinese Medical Equipment Journal 1989;0(02):-
The apparatus introduced in this paper can be used to measure and record the realtime environmental parameters and such physical information of individual protection equipment as the temperature,thermal current and thermal insulating value.The apparatus has several advantages including high accuracy,practicability,reliability and easy to operate.