1.Extracorpoveal Circulation Speed-Measuring Apparatus
Chinese Medical Equipment Journal 1989;0(04):-
This paper introduces a simple speed-measuring apparatus equipped with single-chip microcom- puter,MCS-51.It can be used in wide fields with excellent precision.A progressive method of time sampling is adopted for programming,i.e.transfer the time per revolution to speed (with precision of 0.001s).So the characters of MCS-51,good controlling and running ability,are fully utilized.In the time-measuring pro- gramm,two impulse signals,sampled by photo-electric transformation are wisely adopted to start and stop the counter respectively.
2.Technological transformation to luminous flux of DTG160 single-pan analytical balance
Chinese Medical Equipment Journal 1989;0(04):-
This article analyses the deficiencies of DTG160 single-pan analytical balance and elaborates the basis of its technological transformation.Luminous fluxes of 20 balances are successfully transformed.What' s more,this transformation method is also suitable for other mechanical single-pan or double-pan analytical balance.
3.Extraction of Liver Focal Lesions in Abdominal CT Image Based on Local OTSU and Zone Market Screening
Chinese Medical Equipment Journal 1993;0(05):-
Objective To prepare for extraction of liver focal lesion in view of its characteristics of images. Methods A region of interest in the liver region comprising the focal lesion to create a local image was selected firstly, then the threshold to pre-segment the local image was got automatically by using local OTSU in clusters algorithm, at last mark sifting methods to get red of inner holes and outer dissociate areas to get the final contour was used. Results The algorithm can efficiently extract the focal liver lesion. Conclusion The way of extraction of liver focal lesions with local OTSU and zone market screening is rapid and effective.
4.Fingerprints of Radix Glycyrrhizae by HPLC
Zhaohui WU ; Jiabo LUO ; Wenwei YOU
Chinese Traditional and Herbal Drugs 1994;0(12):-
Objective To establish the HPLC fingerprints of Radix Glycyrrhizae. Methods The RP-HPLC method was used, Zorbax SB C_ 18 column (250 mm?4.6 mm, 5 ?m) was employed; the acetonitrile-1.2% acetic acid (gradient elution) was used as mobile phase, analytic time was 70 min, and detective wavelength was at 254 nm. Results The HPLC fingerprints of Radix Glycyrrhizae were set up. The result showed that 38 peaks were common in different sources. The results of method validation met technical standard of fingerprints. Conclusion The method is stable and reliable with a good reproducibility and provides a reference standard for the quality control of Radix Glycyrrhizae.
5.Expression and significance of neuropeptides in callus of rats after brain injury and tibial fracture
Bing LI ; Zhaohui HU ; Tongqing LUO
Chinese Journal of Tissue Engineering Research 2007;0(02):-
AIM:It is suggested that the peptidergic nerves containing substance P(SP),calcitonin gene-related peptide(CGRP),vasoactive intestinal peptide(VIP),neuropeptide Y(NPY) and tyrosine hydroxylase(TOH) co-exist in bone tissues and distribute in the active bone metabolism area,indicating these peptidergic nerves are closely related with bone growth and development. In this study,the expression of neuropeptides in tibial callus of rats after brain injury was observed. METHODS:The experiment was conducted in the Experimental Animal Center of Guangxi Medical University from February to May 2007. ①130 male Wistar rats of 3-4 months old and 450-550 g were randomly divided into fracture group(n =60),brain injury plus fracture group(n =60) and control group(n =10). ②The right parietal bone of anesthetized rats was exposed,and bone window of 5 mm was opened 2 mm near median line,then moderate brain injury was made by sap pressure,and the rat models of tibial fracture were established. The fracture group was only subjected to cranial bone window,and the control group was not given any treatment. ③The distribution of neuropeptide in tibia and callus succession as well as fracture healing were observed by HE and immunohistochemical staining on postoperatively days 3,7,14,21,28,and 35 days. The callus area in brain injury plus fracture group and fracture group was detected by computed radiography(CR) at 14,21 and 28 days after operation. RESULTS:All 130 rats were involved in the result analysis. ①At early stage after brain injury,there were a quantity of fibrous callus and cartilaginous callus formation in brain injury and fracture group and many neuropeptides immunoreactive nerve fibers in callus were found. Strong immunoreactivites of CGRP,SP,VIP,NPY,TOH occurred to osteogenitor cells and chondroblast,which proliferated in thickened endothecium. ②In brain injury and fracture group on day 14,the chondrocyte group was enlarged and subperiosteum chondrocyte layer was thickened;on day 21,bone trabecula was significantly thickened,and cartilage islands were increased;on day 28,there were still quantity of fibrous callus and cartilaginous callus,and sparse woven bones surrounding chondrocyte groups. In fracture group,periosteal reaction was slight,and fibrous callus was few;osteogenesis in bone and cartilage occurred,but mainly in bone. Moreover,the fracture healing was remarkably later than brain injury and fracture group. ③Callus area in brain injury and fracture group was larger than that in fracture group on days 14 and 21(P
6.THE PRELIMINARY STUDY ON THE CHANGES IN THE EXPRESSION OF G PROTEINS ? SUBUNIT mRNA IN THYROID TUMOR
Zhaohui LU ; Guochun LUO ; Changy PAN
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
To investigate the changes in the expression of G proteins ? subunit mRNA in non functioning thyroid adenoma (NFTA) and thyroid papillary cancer (TPC). Eleven thyroid specimens were obtained during surgery, 6 of which from patients with NFTA and 5 from patients with TPC. The expression levels of stimulating and inhibiting G protein ? subunit mRNAs were determined by reverse transcription polymerase chain reaction (RT PCR). The expression levels of Gsa mRNA in TPCs were significantly higher than those in normal thyroids and NFTAs( P
7.Alopecia areata: a clinical analysis of 118 cases
Min LUO ; Jinhua HUANG ; Zhaohui LIAO
Chinese Journal of Medical Aesthetics and Cosmetology 2001;0(06):-
Objective To investigate clinical features of alopecia areata such as sex, age, and subjective symptoms, and relationships between these factors and disease severity. Methods Clinical materials of patients who were diagnosed as alopecia areata were collected. The role of sex was analyzed in the disease and the correlation between disease severity and sex, age or psychological factors was analyzed. Results 118 patients including 101 cases of localized alopecia areata (AA), 5 alpecia totalis (AT) and 12 alopecia universalis (AU) were collected. The ratio of male to female was 1.2:1 and there was no correlation between sex and disease severity. The patients were from 1 to 76 years old while average age was 31.3?1.3 years, and that of the female patients was 28.9?1.9 and the male was 33.2?1.8; The median course was 2.5 months, while AA was 2 months, and AT/AU was 18 months; 14.4% patients (17/118), including 11 cases of AA and 6 AT/AU had subjective symptoms; 20.3% patients (24/118) had psychological factors before onset, 60.2% patients (71/118) had difficulties in sleeping, nail changes were found in 15.2% patients (18/118), and ocular symptoms were found in 5.9% patients (7/118), 5.9% patients (7/118) had family history, 3.4% patients (4/118) were accompanied by disease of thyroid gland, 1.7% patients (2/118) were accompanied by vitiligo, TGA and TMA levels elevated abnormally in 4.8% patients (3/62). Conclusion Alopecia areata often affects young to middle-aged people, and there is no correlation between sex and disease severity; Female patients are younger than male; A few patients are induced by psychological factors, and some accompanied by other autoimmune diseases. AT/AU is easier to have subjective symptoms than AA.
8.Study on influence of compatibility on amygdalin in Mahuang Decoction by HPLC
Zhaohui WU ; Jiabo LUO ; Xiaotian HU
Chinese Traditional and Herbal Drugs 1994;0(03):-
Object To set up the quantitative method of amygdalin in decoctions prepared from various combinations of the recipe named Mahuang Decoction by HPLC and to determine the change of amygdalin contents in different decoctions and study the influence of compatibility on the contents of amygdalin in decoctions. Methods By L 8(27) orthogonal design and statistic analysis (SPSS 10.0), eight decoctions with Semen Armeniacae Amarum were prepared and analyzed, their amygdalin contents were determined by HPLC. Results The method was simple, accurate, and sensitive and was not interfered by other constituents in the prescription, it can be used to determine the contents of amygdalin in Mahuang Decoction. Influence of Herba Ephedrae, Ramulus Cinnamomin, and Radix Glycyrrhizae on the contents of amygdalin in decoctions were insignificant. Interactions between two of three separately were insignificant too. Conclusion The content of amygdalin in Mahuang Decoction is not markedly influenced by Herba Ephedrae, Ramulus Cinnamomin, and Radix Glycyrrhizae.
9.Association between health literacy and infectious diseases in foreign populations
Zhaohui YANG ; Hui WANG ; Ping LUO
Chinese Journal of Medical Library and Information Science 2017;26(2):23-27
Health literacy is the key factor that influences the public to understand health information and to make effective decision for their health and nursing. Papers on the association between health literacy and infectious dis-eases were thus retrieved from Medical Literature Database, PubMed and Nursing Database from 1999 to 2016 and the influence of health literacy on infectious diseases was analyzed, which showed that there were papers that repor-ted the knowledge and use of antibiotics, immunization for influenza and measles, sexual behavior-transmitted dis-ease and virus hepatitis with tuberculosis, malaria, hand sanitization and infectious diarrhea seldom involved, and that health literacy was associated with preventive measures.
10.Clinical study on evaluation of pulmonary recruitment with different body position and positive end-expiratory pressure mode in stage of mechanical ventilation in severe acute respiratory distress syndrome
Kaiyuan HE ; Zhenji LUO ; Zhaohui WANG ; Dongmei LI ; Lixiu WU
Chinese Journal of Postgraduates of Medicine 2017;40(6):504-508
Objective To evaluate the effects of pulmonary recruitment (RM) in severe acute respiratory distress syndrome (ARDS) with different body position and positive end-expiratory pressure (PEEP) mode in stage of mechanical ventilation. Methods From June 2013 to June 2016, 80 cases of ICU hospitalized patients with clinical data were enrolled, and they lay in the prone or supine position (prone position group and supine position group, each of 40 cases). The hemodynamic parameters including heart rate (HR), central venous pressure (CVP) and peripheral arterial pressure, respiratory mechanics index including respiratory rate (RR), respiratory system compliance (Crs) and platform pressure (Pplate), and the changes of blood gas analysis index were monitored to observe the effects of RM in different positions with positive end expiratory pressure increasing method. Results The levels of oxygenation index and arterial partial pressure of oxygen (PaO2) were improved 3, 5 and 7 d after treatment compared with those 1 d after treatment (P<0.05), and they were improved significantly in prone position group than those in supine position group 3 and 5 d after treatment (P<0.05). The levels of RR, Crs and Pplate 15 min, 30 min, 1 h, 6 h, 12 h and 24 h after RM had significant differences compared with those before RM (P<0.01). The levels of HR, CVP, peripheral arterial pressure 15 min, 30 min, 1 h, 6 h, 12 h and 24 h after RM had no significant differences compared with those before RM (P>0.05). Conclusions For patients with severe ARDS, early implementation of prone position ventilation combined with PEEP increasing method re-expansion treatment is safe and reliable. It can effectively improve oxygenation level and help to improve the survival rate.