1.Use of bioelectrical impedance analysis measurement in malnutrition patients
Guohao WU ; Zhaohan WU ; Zhaoguang WU ;
Parenteral & Enteral Nutrition 1997;0(02):-
Objectives:The purpose of this study was to measure the body composition of malnourished patients by bioelectrical impedance analysis. Methods:Body composition was measured by bioelectrical impedance analysis in 68 malnourished patients and 78 healthy subjects. Results:The investigation showed that malnutrition patients were characterized by a depletion in fat mass,fat free mass, body cell mass,intracellular mass and an expansion of extracellular mass( P
2.Dual-energy X-ray absorptiometry in the assessment of body composition in malnutrition patients
Guohao WU ; Zhaohan WU ; Zhaoguang WU ;
Parenteral & Enteral Nutrition 1997;0(02):-
Objectives:The purpose of this study was to measure the body composition of malnourished patients by dual energy X ray absorptiometry. Methods:Body composition was measured by dual energy X ray absorptiometry in 56 manlnourished patients and 72 healthy subjects. Results:Compared with control,patients had lost?(on average)?17.8?kg of body weight (P0.05). Conclusions: Reduced body weight in malnourished patients was due to loss of fat tissue and lean body mass.
3.APPLICATION OF TOTAL NUTRIENT ADMIXTURE SOLUTION IN PARENTERAL NUTRITION
Dexiang HUANG ; Zhaohan WU ; Zhaoguang WU
Acta Nutrimenta Sinica 1956;0(02):-
Lipid emulsion, glucose, amino acids, electrolytes, vitamins and trace ele- ments were mixed in a definite order to prepare 10 different total nutrient admixture solutions. The pH and osmolality of these solutions did not change significantly during 14 days of storage at 4℃.Mean diameters of the lipid particles on different occasions for the different solutions varied from 0.3135?0.1012?m to 0.4813?0.1893 ?m. 94.93% of particles were less than 0.6 ?m, and none greater than 6?m. Cultures were all negative.74 patients received 1,796 such infusions. No adverse clinical reactions or abnormal laboratory parameters were observed. Patients on treatment for more than one week showed improved nitrogen balances. Serum transferrin and albumin were increased to varying levels when treatment was for more than two weeks.
4.Application of anterior intervertebral fusion with SOLIS for the treatment of traumatic cervical disc protru-sion
Zhaoguang MAO ; Qingxin WU ; Chunde LL ; Shenggen XU ; Tianyue ZHU
Chinese Journal of Primary Medicine and Pharmacy 2008;15(10):1593-1594
Objective To evaluate the application of SOLIS in the surgery on anterior intervertebral fusion for the treatment of traumatic cervical disc protrnsion. Methods 53 traumatic single segment cervical disc protrusion were divided into three groups randomly. The A group (SOLIS) :n=18, SOLIS filled with autocancellous bone were implanted between the cervical vertebrae. The B group(Syncage) :n =16, as the first group Syncage filled with auto-cancellous bone were implanted. The C group:n=19,anterior cervical decompression and fusion with bone autograft and internal fixation with ACPS. The operations of the surgery on anterior cervical decompression in three groups were the same. Recovery of nerve function was observed by JOA score and the fusion state, stability and changes of interver-tebra height of fusion segment were evaluated by X ray. Results The average duration of the follow-up was 16.5 months in 53 cases. Bony fusion could be found 3~9months after operation in all cases. In all A (SOLIS) group cases,the movement of the implanted $OLIS Cage were not found. The heights of the cervical intervertebral spaces and the physiological curvature were restored without loss in the duration of follow-up. The average JOA was(10.4±2.4) be-fore operation and(14.9±2.0)after operation. There was highly significant variation between the former and the latter (P<0.01). In the B (Syncage)group,5 cases had cage subsidence, therefore the height of intervertebra and the phys-iological curvature were lost. The average JOA was (10.6±2.5) before operation and (13.2±2.3) after operation.There was significant variation between the former and the latter(P<0.05). In the C group the third group, the move-ment of the fixed titanium plate were not found in the duration of follow-up in 18 cases. The titanium plate fixation was loose in 1 case. The average JOA was(10.5±2.4) bofore operation and(15.1±1.9) after operation. There was high-ly significant variation between the former and the latter(P<0.01). After operation,there was significant difference in the JOA score between the A group and the B group,between the C group and the B group(P<0.05) ,and there was no difference between the A group and the C group(P>0.05). Conclusion Treatment of single segment prolapse of the cervical intervertebral disc with SOLIS cage has some advantages such as higher fusion rate, higher recovery rate of nerve function and low rate of loss of intervertebra] height.
5.Comparison of therapeutic effects of transureteroscope holmium laser lithotripsy and retroperitoneal laparo-scopic ureterolithotomy for unilateral upper ureteral calculi
Zhaoguang WANG ; Guiming SUN ; Guolin LIU ; Shutian WU
Chinese Journal of Primary Medicine and Pharmacy 2014;(17):2614-2616
Objective To compare the therapeutic effects of transureteroscope holmium laser lithotripsy ( URL) and retroperitoneal laparoscopic ureterolithotomy ( RLU) for unilateral upper ureteral calculi and evaluate the selection of indications and clinical value of URL and RLU .Methods 37 patients were enrolled into the study . 14 patients received URL ,23 patients received RUL .Double-J stent was routinely indwelled in both groups .The oper-ation time,hospitalization time,clearance rate of the stone and incidence of postoperative complications .Results The stone clearance rate after postoperation of RLU group was 100%, which was significantly higher than that of URL group 64.4%(χ2 =4.15,P<0.05).The mean operation time in RLU group was(132.0 ±7.8)min,which was sig-nificantly longer than URL group(46.5 ±7.2)min(t=6.23,P<0.05).The mean intraoperative blood loss of RLU group was(38.0 ±4.6)mL,which was significantly higher than URL group (10.0 ±3.2)mL(t=5.20,P<0.05). The postoperative complication rate of RLU group was 8.7%,which was significantly lower than URL group 21.5%(χ2 =4.06,P<0.05).There was no significant difference in hospitalization time and stone clearance rate between the two groups(P>0.05).Two cases converted to operation in URL group ,while only 1 case converted to operation in RLU group.Conclusion Laparoscopic ureterolithotomy has a higher stone clearance rate and shorter operation time compared with ureteroscopic lithotripsy .Laparoscopic ureterolithotomy is a safe and effective therapeutic method for unilateral upper ureteral stones .
6.Content Analysis of 5 Kinds of Heavy Metal in Yougui Pills
Cunjin LI ; Ting XIE ; Yunfeng ZHOU ; Jiehua DENG ; Zhe WU ; Zhaoguang HUANG
China Pharmacy 2021;32(19):2377-2382
OBJECTIVE:To investigate the contents of 5 kinds of heavy metal as copper (Cu),arsenic(As),cadmium (Cd),mercury(Hg)and lead (Pb)in Yougui pills ,and to evaluate its safety risk. METHODS :Using yttrium (89Y),indium (115In)and bismuth (209bi)as internal standard ,the contents of each element were determined by ICP-MS. ICP-MS condition included that atomization gas flow rate was 0.95 L/min,auxiliary gas flow rate was 1.2 L/min,plasma gas (argon)flow rate was 18 L/min,pump speed was 30 r/min. RF power of inductively coupled plasma was 1 200 W,the voltage in simulation stage was 1 750 V,the voltage in pulse stage was 1 300 V,the voltage of deflection device was -12 V,and the detector was in analog and pulse dual-mode. The determination methods of various elements were investigated ,and 45 batches of marketed Yougui pills were determined. Hazard index (HI)was used to analyze the non-carcinogenic risk of each element and calculate the maximum residual limit(MRL)of each element. RESULTS :The linear range of Cu ,As,Cd,Hg and Pb ranged from 10-200,1-50,0.4-30,0.2-6 and 2-100 μg/L(all r>0.999 0),respectively. The limits of quantitation were 0.67,0.23,0.20,0.07,0.27 μg/L. The limits of detection were 0.20,0.07,0.06,0.02,0.08 μg/L. RSDs of precision,stability and reproducibility tests were all lower than 3.5% (n=6 or n=5). Average recoveries were 92.96%-100.89%(RSD=2.23%-3.62%,n=3). Average contents of Cu ,As,Cd,Hg and Pb in 45 batches of Yougui pills were 2.72,0.28,0.07,0.05,0.62 mg/kg,and superimposed HI of each element was less than 1. The contents of 5 kinds of heavy metals in Yougui pills were lower than the proposed MRL (MRL of Cu ,As,Cd,Hg and Pb were 20,2,1,0.2,5 mg/kg or 111.11,4.44,2.22,1.48,8.89 mg/kg respectively ). CONCLUSIONS :Established method can be used for the determination of content of 5 kinds of heavy metal in Yougui pills ;the heavy metal pollution rate of marketed Yougui pills is low and the safety risk is small.