With the constant development of medical science and technology, great changes have taken place in the role of medico-technical departments. In light of the basic characteristics and development situation of medico-technical departments in modern hospitals, the paper proposes the following ways to step up their management: ①enhancing organizational management and raising the level of scientific management; ②reinforcing standardized management and improving the quality of diagnosis and treatment; ③tightening personnel management and bettering the quality of technical personnel; ④strengthening horizontal ties and coordinating relations with clinical departments; ⑤augmenting disciplinary integration and bringing into full play the role of advantaged specialty groups; ⑥giving full play to the “two initiatives” and setting up a highly efficient operational mechanism within the departments.