1.Treatment of arteriovenous malformation in jaw bone
Journal of Practical Stomatology 1995;0(04):-
Objective: To study the effective treatment methods of arteriovenous malformation(AVM) in jaw bone through retrospective review. Methods:33 patients with jaw AVM were analyzed by history, treatment methods and outcome. Results: Among the 33 patients 6 were treated by embolization only, 12 by curretting, 10 by resection of the bone lesions. The cure rate in the three groups was 2/6,11/12 and 10/10 respectively. Conclusions: Embolization combined with curretting may be the effective methods to treat facial bone AVM without resection of bone.
2.Correlation between the surgical effect and clinical factors in retinal detachments with macular hole
Chinese Journal of Rehabilitation Theory and Practice 2005;11(6):485-486
ObjectiveTo investigate the correlation between the surgical effect and clinical factors in retinal detachments with macular hole patients.Methods71 patients were picked up from the rhegmatogenous retinal detachment (RRD) database in our hospital. All patients were well informed with clinical data and followed up. Logistic regression statistical analysis was performed to analyze correlation between the effect of operation and clinical factors.ResultsAll patients obtained successful retinal replacement and macular hole closure, but retinal detachment was relapsed in 10 patients from 3 days to 3 years after operation. Effect of retinal replacement was related with proliferative vitreoretinopathy (PVR) grade and course (P<0.05), while eyesight improvement was related with PVR grade, age and course (P<0.05).ConclusionAge, PVR grade and course affect the surgical effect.
3.Multidrug resistant gene mdr1 expression in oral squamous cell carcinoma before and after chemotherapy
Jie ZHANG ; Jianguo ZHANG ; Fuyun ZHAO
Journal of Practical Stomatology 2000;0(05):-
Objective: To compare the expression of multidrug resistant gene( mdr 1 ) in oral squamous cell carcinoma (SCC) before and after chemotherapy. Methods: Mdr 1 gene expression in 21 cases of oral SCC was detected before and after chemotherapy by dot blot hybridization, Results: Before and after sigle drug chemotherapy mdr1 mRNA(?10 5 copies/?g) in SCC tissue was 1.98?1.72 and 3.74?3.24( P
4.Observation on Microsurgery of the Willis Circle by Combined Frontotemporal-Orbitozygomatic Approach
Zhigang ZHANG ; Xianrun YUAN ; Jie ZHAO
Journal of Chinese Physician 2001;0(09):-
Objective To get more detailed information about the microsurgery of the Willis circle,in order to provide evidence of clinical operation.Methods The microsurgical anatomy of the Willis circle via combined frontotemporal-orbitozygomatic approach was studied in 5 adult cadaver brains under microsurgical scope. Results The Willis circle was composed of anterior communicating artery (ACOA), A 1 segments of the right and left anterior cerebral arteries (ACA), right and left internal carotid arteries(ICA) right and left, posterior communicating artery (PCOA), Pi segments of the right and left posterior cerebral arteries (PCA).The variation are present obviously in A 1 segment of the ACA. The outer diameter of left A 1 segment are larger than that of right ones. There are many perforating arteries of each part of Willis circle. Most of them arise from their original arteries, then course medial-superiorly to the optic tract, the pituitary stalk, the optic chiasm, the thalamus, hypothalamus, the floor of third ventricle, basal nuclei and internal capsule etc blood supplied areas. Conclusion To understand the microsurgical anotamy of the Willis circle and protections against its penetrating branches perfectly are the key to gain a good curative effect during the concerned operation .
5.Relationship between Gastric Acid and Stress Ulcer Produced by Water Immersion in Young Rats
jie, ZHAO ; wen, ZHANG ; xiao-mei, TONG
Journal of Applied Clinical Pediatrics 2006;0(19):-
Objective To establish the animal model with stress ulcer(SU) and probe the relationship between the gastric mucosal injury and lasting stress time,the dynamic structural changes of pH of gastric juice.Methods Twenty-four SD young rats were randomly divided into 4 groups:control group,45 min(groupⅠ),90 min(groupⅡ),3 h(groupⅢ)groups under water immersion restraint stress(WRS).The change of gastric mucosal ulcer index(UI),pH of gastric juice were observed.Results Acute gastric mucosal damage was induced by WRS,with the WRS time prolonged,UI increased gradually and pH of gastric juice remarkably decreased in experimental rats.UI was positively rela-ted with stress time(r=0.957 P
6.Diagnosis and treatment of childhood bronchiolitis obliterans
Yuqi ZHAO ; Yongju ZHANG ; Jie ZHANC
Chinese Journal of General Practitioners 2011;10(12):899-900
Clinical data of 28 cases of childhood bronchiolitis obliterans treated from September 2008 to November 2010 were retrospectively analysis.Pulmonary high-resolution CT (HRCT) showed that bronchial wall thicken was seen in all 28 patients,the mosaic pattern in 26 cases,patchy shadows in 18 cases,bronchiectasis with typical signet ring sign in 2 cases,atelectasis in 2 cases without pleural effusion.Pulmonary function tests and flexible bronchofiberscopy were performed in 6 cases,which showed the inflammation in bronchial tunica intima and obstruction of small airway.Blood routine,blood sedimentation,c-reaction protein,TORCH,hepatic function,renal function and immune function were normal.Patients received comprehensive treatment with methylprednisolone,clarithromycin and montelukast.The clinical conditions of 28 cases were improved with varying degrees after treatment and no significant side effects were observed.
7.Application of retroperitoneal laparoscopic partial nephrectomy in the treatment of unilateral multifocal renal tumors
Qiang ZHAO ; Qian ZHANG ; Jie JIN
Chinese Journal of Urology 2014;35(4):241-244
Objective To discuss the safety and efficacy of retroperitoneal laparoscopic partial nephrectomy in the treatment of unilateral multifocal renal tumors.Methods The data of 12 patients with unilateral multifocal renal tumors managed with retroperitoneal laparoscopic partial nephrectomy between 2009 and 2012 were reviewed retrospectively.The 12 patients had a mean age of 42 years (28 to 62) and body mass index of 23.5 kg/m2 (18.6 to 29.3),including 4 males and 8 females.Four cases were in the left side,7 cases were in the right side,and 1 case had bilateral renal tumors.The diameter of renal tumors ranged from 0.5 cm to 4.7 cm,and all tumors were projected on the surface of kidney.Nine cases were diagnosed as renal cell carcinoma,and 3 cases were diagnosed as angiomyolipoma before operation.All patients underwent retroperitoneal laparoscopic partial nephrectomy under general anesthesia,while 1 patient with bilateral renal tumors experienced radical nephrectomy of the contralateral renal tumor 3 months after the first operation.Results All the oprations were successful without conversion to open surgery.The mean renal artery cut off time,operative time,estimated blood loss and hospital stay were 36 min (26-60),126 min (75-184),142 ml (50-300) and 5 d (3-9),respectively.No complication occurred and 1-week postoperative serum creatinine was (78.1 ±8.1)μmol/L.Histopathological study revealed 9 cases of renal cell carcinomaand 3 cases of angiomyolipoma.During the follow-up for 33 months (13-51),1 patient with yon Hippel-Lindau syndrome was operated with ipsilateral radical nephrectomy for a local recurrence while the remains had no local recurrence or metastasis.Conclusions For localized and exogenous unilateral multifocal renal tumors,retroperitoneal laparoscopic partial nephrectomy is feasible and safe.Those who have hereditary and/or malignant renal tumors should be monitored closely.
8.Retroperitoneal laparoscopic radical nephrectomy versus transperitoneal laparoscopic radical nephrectomy: a meta-analysis of safety and efficiency
Qiang ZHAO ; Qian ZHANG ; Jie JIN
Chinese Journal of Urology 2014;35(5):326-329
Objective To compare the safety and efficiency of retroperitoneal laparoscopic and transperitoneal laparoscopic radical nephrectomy by meta-analysis.Methods A systematic review of the literature about laparoscopic radical nephrectomy was performed,searching Medline,Embase,Cochrane library,CBM,CNKI,VIP and Wan Fang database from January 2000 to October 2012.The key words were transperitoneal,retroperitoneal,laparoscopy,radical nephrectomy.Two researchers evaluated the quality of included studies.A meta-analysis was conducted using Review Manager 5.0 software.Results Nine controlled clinical studies were concluded,including 1 306 patients (520 in retroperitoneal group and 786 in transperitoneal group).The extracted data were comparable.Meta-analysis results showed that significant difference existed in operative time and complication rate (OR =16.23,95% CI 1.62,30.84; OR =2.44,95%CI 1.35,4.41) (P<0.05).It seemed that the retroperitioneal laparoscopic radical nephrectomy was prior to the transperitoneal laparoscopic radical nephrectomy in those items.There was no significant difference between transperitoneal and retroperitioneal laparoscopic radical nephrectomy in incision length,estimated blood loss,stay-in hospital,conversion rate,5-year disease-free survival and 5-year overall survival (P> 0.05).Conclusions Retroperitoneal laparoscopic radical nephrectomy demonstrated significant lower operative time and complication rate than those in transperitoneal laparoscopic radical nephrectomy.However,there is no significant difference in efficacy.Each center can choose a modality according to their convention.
9.Experience of adult inguinal hernia treated with the open preperitoneal herniorrhaphy under local anesthesia
Liang ZHAO ; Jie ZHANG ; Zuojun LIU
International Journal of Surgery 2014;41(7):464-466
Objective To investigate experience in adult inguinal hernia treated with the open preperitoneal herniorrhaphy.Methods Eight hundred and twenty-six cases were retrospectively analyzed from February 2004 to December 2011 in our hospital.The effect of operative methods and treatment were observed simultaneously.Results All the patients were cured completely without special complications; Followed up for 12 months,some negative factors such as incision infection,recurrence,special discomfort,and chronic pain have not been appeared.Conclusions The open preperitoneal herniorrhaphy under local anesthesia for adult inguinal hernia is safe,reliable and effective.
10.Current situation of Xinjiang medical students′AIDS discrimination and influence factors analysis
Jie WU ; Jinfeng MA ; Zhao ZHANG
Chongqing Medicine 2015;(11):1529-1532
Objective To understand the status quo of AIDS discrimination among Xinjiang medical college students and its influence factors .Methods By using the stratified cluster sampling method ,583 students in a Xinjiang medical college were conduc‐ted the AIDS related questionnaire investigation .Results If medical undergraduate students found that the schoolmates carried HIV ,18 .01% of college students would not directly contact with them ,45 .97% of medical college students would not give sympa‐thy and concern ,31 .22% of students would not keep normal communication with them ,53 .17% of medical college students thought that they should drop out of school to go home ,32 .76% of medical college students would not keep a secret to the outside world ;40 .99% of the medical college students would advise them to restrain their own behaviors ,24 .87% of medical college students would choose to report it to the teacher or leader .By the multivariate analysis of covariance ,gender ,nationality ,family monthly in‐come ,origin of students ,AIDS related knowledge ,etc .were the factors affecting the level of AIDS discrimination .Conclusion The medical college students have a certain degree of discrimination to the AIDS patients ,learning the AIDS related knowledge should be strengthened for reducing the fear psychology on AIDS ,thus to eliminate the discrimination towards AIDS .