1.Cognitive processing of Chinese characters between hearing-disabled and normal people
Chinese Journal of Tissue Engineering Research 2005;9(12):234-235
BACKGROUND: At present, there are some researches on the cognitive identification of Chinese characters at home or abroad, however, most of them are based on the normal and healthy people.OBJECTIVE: To investigate the processing styles of optical information on phonemic code, graphic code and semantic code of Chinese haracters between hearing-disabled and normal people.DESIGN: Retrospective, observational and compared analysis based on the hearing-disabled as research subjects and the normal as the controlled group.SETTING: Department of education in a university.PARTICIPANTS: This study was completed in Xi' an between October 2001 and April 2002. With the mean age of 17 years and half in gender, 20hearing-disabled people, who were in grade 6 to grade 8, were selected from the Second School for the Deaf and Dumb in Xi' an. Inclusion criteria: The hearing loss of people was more than or equal to 92 dB. Exclusion criteria:People with acquired hearing-disabled were excluded. At the beginning of study in primary school, they were accepted oral training and taught Chinese pinyi, but gesture was the main communicated style in their daily life. With the mean age of 15 years and half in gender, 28 normal people, who were in grade 3, were selected from the No. 99 Middle School in Xi'an.METHODS: This study showed with serial opticum. The diagnostic method was compared with the cognitive identification of the three kinds of Chinese characters between the hearing-disabled and the normal respectively.phonemic code, graphic code and semantic code between hearing-disabled characters between hearing-disabled and normal people.RESULTS: The results showed that the function of graphic code in visual processing was strongly correlated with recognition of words of Chinese characters than the phoneme code and semantic code in both the hearing-disabled and hearing children. For hearing-disabled children, the alternative was the direct access that a semantic code was produced directly from a translation of the graphic code, however, the hearing children used the strategies of grapheme-phoneme conversion rules to interpret the meaning of words.CONCLUSION: The analysis of various results showe that no significant differences of mental processing are found between the hearing-disabled and hearing children. Perhaps both the direct access and the grapheme-phoneme conversion will be a comprehensive information processing activated each other.
2.Clinical analysis of 13 cases of spontaneous intracranial hypotension syndrome
Clinical Medicine of China 2009;25(2):158-159
Objective To study the clinical and imaging characteristics as well as cerebrospinal fluid chan-gea(CSF) of spontaneous intracranial hypotensian syndrome (SIHS).Methods The clinical characteristics, CSF and imaging data of 13 patients diagnosed as SIHS were retrospectively analyzed.Results All the 13 patients had orthostatic headache accompaning one or more numerous symptoms including nausea, vomiting, dizziness, diplopia and neck stiffness.All the patients had low CSF pressure,which was below 60 mm H2O and high CSF protein was in 5 patients, 8 had increased white cell counts and 9 had increased red cells counts;CT was performed in all patients.On CT scan the subdural effusion or small ventricles were compressed in 4 patients.MRI typically revealed diffused pachymeningeal enhancement in 2 patients;All the patients experienced relief of symptoms through conventional treatment.Conclusion Orthostatic headache is the most typical symptom in spontaneous intracranial hypotension syndrome and diffused pachymeuingeal enhancement is the most common imaging manifestation, and CSF hypovol-emia is the basis of pathophysiology of spontaneous intracranial hypotension syndrome.
3.Development of the group intelligence scale for military personnel ( Part B)
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(8):754-756
ObjectiveTo develop the group intelligence scale for Military Personnel ( Part B),and examining its reliability and validity of the scale.MethodsFollowing the intellectual shock theory,crystal and fluid intelligence theory,the group intelligence Scale for Military Personnel (Part B) had been constructed,which including two subscales,each subscale was divided into two subtests.The data was collected in 1200 military personnel who were chosen by random cluster sampling,then employing SPSS17.0 and AMOS7.0 for item analysis,reliability and validity,analysis of confirmatory factor.Resultsthe subtests' average index of difficulty was 0.55 ( 0.42 ~0.75 ) ; Discrimination index was 0.44 (0.33 ~ 0.52) ; the test-retest reliability between subtests and total scale ranged from 0.796 to 0.891 ; Cronbachs'a coefficient ranged from 0.619 to 0.892; and the split-half reliability ranged from 0.538 to 0.844; exploratory factor analysis revealed that four factors of the scale (including normal knowledge and generalizability,insight and word explain,picture completion and figure inference) could explain 59.067% of total variance.Furthermore,analysis of confirmatory factor indicated that the four factors model established in the present study fitted the sample data well.ConclusionThe item analysis,reliability and validity of the newly developed group intelligence scale for military personnel (part B) can meet the basic requirements of psychometrics.
4.Non-aneurysmal perimesencephalic subarachnoid hemorrhage
International Journal of Cerebrovascular Diseases 2015;23(4):301-305
As a special type of subarachnoid hemorrhage,the prognosis of non-aneurysmal perimesencephalic subarachnoid hemorrhage (NAPSAH) is good.In recent years,with the development and popularization of neuroimaging technology,people have gradually deepened the awareness of the disease.This article reviews the progress in the diagnosis and treatment of NAPSAH.
5.Quantitative evaluation of vestibular function, balance function and optokinetic function in elderly person
Chinese Journal of Tissue Engineering Research 2005;9(23):231-233
BACKGROUND: Old people above 80 years old have a high incidence of dizziness and tumble, which are associated with weakening vestibular function, balance function and optokinetic function.OBJECTIVE:This study was designed to make a quantitative evaluation of vestibular function,balance function and optokinetic function in people over 80 years old.DESIGN:It was a quantitative study on posture function(vestibular and balance function),auditory function(frequency audiometry)and visual function (optokinetic function) in elderly persons.SETTING:Department of Otolaryngology ,General Hospital of Chinese PLA.PARTICIPANTS:Totally 41 old male inpatients with systemic diseases in Rehabilitation Department of the General Hospital of Chinese PLA, with an age from 80 to 94 were selected from March 1993 to January 1994.Of them,12 had tinnitus,20 had dizziness.During the same period,old cadres including 11 males and 7 females aged from 60 to 79 years with normal findings of physical examinations were selected as controls. No participant in this group suffered from tinnitus, deafness and dizziness. All the participants were voluntary.METHODS: Patients underwent full-scale otolaryngological examinations.Audiometry consisted of battery of tests including frequency audiometry and evoked auditory brainstem responses(ABR). Vestibular function (posture) was assessed by vestibular-ocular reflexes. Participants accelerated from 1 /s to 90 /s. Then, the angular speed was kept until the nystagmus disappeared,at the time a sudden stop was made.Changes in nystagmus during the tests were recorded.The eyes firstly turned to left and 10 minutes later turned to right.Slow-phase angular velocity was recorded and the imbalanced left/right rate was calculated.Vestibularspinal reflex (VSR) was measured using balance beam and the length of the sway of the center of gravity (CG) and the sway velocity of CG were all calculated. Balance tests using a cursor were employed to examine the central optokinetic system, including sweeping, tracking, and optokinetic responses.MAIN OUTCOME MEASURES: Frequency audiometry, vestibular-ocular reflexes, and vestibular-spinal reflex and optokinetic responses were examined to assess the posture function, auditory function and visual function in elderly persons over 80 years old.And the results were compared with those of balance function tests and visual function tests in old population aged from 60 to 79 years old.RESULTS:Practically,the number of old participants over 80 years old receiving the tests of frequency audiometry, vestibular-ocular reflexes, and vestibular-spinal reflex and optokinetic responses were 41,24,39,40 and 34 respectively;The number of 60-79 participants receiving balance tests and visual tests were 18 and 10.Individuals refusing to participate were omitted. ① Auditory function:In 41 elderly persons >80 years,13 ears (16%) had a normal middle frequency audiometry, 69 ears (84%) had a loss of hearing. ② Posture function: 15 (62%) had normal vestibular-ocular reflexes, and 9 (38%) had abnormalities in vestibular-ocular reflexes.Ten (26%) had a normal vestibular-spinal reflex and 29 (74%) had an abnormal vestibular-spinal reflex.③ Balance function:Of all the variables of balance function,the length of the sway of CG and the sway velocity of CG were most valuable. In populations in both brackets, the length of the sway of CG and the sway velocity of CG in eyes-closed condition were longer and faster than those in eyes-opened .condition (P < 0.01). In over 80 years group,the length of the sway of CG and the sway velocity of CG were longer and faster than in 60-79 group (P < 0.01). ④ Optokinetic responses:Optokinetic plus were not obviously different between over-80 group and 60-79 group (P > 0.05) and the latent period of sweeping and the distortion of tracking were significantly longer and greater in former group than in later(P < 0.05-0.01 ).CONCLUSION:Most of the elderly persons over 80 years have a decrease in auditory and posture functions.Their optokinetic and balance functions are degenerated more severely than 60-79 years old population.
6.Implemented observation on three-week rehabilitation intervention procedure in patients with acute myocardial infarction in cardiological department of municipal hospital
Chinese Journal of Tissue Engineering Research 2005;9(19):198-200
BACKGROUND: The rehabilitation treatment for acute myocardial infarction has started since 1980' s, but it has not been popularized yet in municipal hospitals due to limited conditions.OBJECTIVE: To probe into the possibility of 3-week rehabilitation intervention in patients with acute myocardial infarction implemented in municipal hospitals.DESIGN: Controlled retrospective analysis was designed.SETTING: Department of Cardiology of YingKou Center Hospital.PARTICIPANTS: Sixty cases of acute myocardial infarction were collected in Department of Cardiology of Center Hospital in Yingkou City in 1996 and they were taken as experimental group. Totally 58 cases of acute myocardial infarction hospitalized in 1986 were taken as the control. In experimental group, 44 cases were males and 16 cases females, aged varied from 34 to 79 years; of which, 45 cases were diagnosed as cardiac dysfunction and cardiac arrhythmia. The situation in the control was near basically to that in experimental group. During the intervention, in experimental group, 10 cases presented chest oppression, 3 cases were afraid to accept the intervention; but by monitoring and explanation, all of those accomplished the experiment.METHODS: In the control, only rational clinical management was given. In experimental group, at the same time of clinical management implemented,the rehabilitation treatment for 3 weeks was carried out for patients with acute myocardial infarction, aiming to earlier movement, earlier getting up, earlier discharge. The rehabilitation procedure stood by gradually increased exercise amount and individualization and it was adjusted according to age, situation of sickness and psychological state, etc. For instance, if the signs of over-endurance presented, the exercise would stop temporarily or the exercise intensity be reduced.MAIN OUTCOME MEASURES: Comparisons of exercise endurance, recovery time of exercise and hospitalizing time in 3 weeks of two groups.RESULTS: The patients in experimental group all accomplished 3-week rehabilitation intervention. In experimental group, the cases, in which, the exercise endurance was up to 5 to 6 equivalents 3 weeks after acute myocardial infarction, were more than the control (78%, 12%, P < 0.05). The cases that were able to go up-down stairs were more than the control(83%, 7%, P< 0.05) . The cases hospitalized < 3 weeks were more than the control (78%, 10%, P <0.05).CONCLUSION: It is practical and safe to carry on rehabilitation procedure for acute myocardial infarction in municipal hospital. Rehabilitation exercise at the early stage accelerates remarkably the recovery of acute myocardial infarction.
7.Research progress of relationship between each component of metabolic syndrome and hypertension
Chinese Journal of cardiovascular Rehabilitation Medicine 2015;24(1):110-113
Metabolic syndrome (MS)is a syndrome of multiple metabolic abnormality aggregation,including over-weight,hypertension,glucose and lipid metabolic abnormality and insulin resistance etc.Some researches demon-strated that over 80% EH patients may be complicated with MS,those patients with EH+MS possess higher risk for cardio-and cerebrovascular diseases than pure EH patients.This article made an overview on research about rela-tionship between EH and MS in recent years.
8.Problems of rituximab as the targeting therapy for non-Hodgkin lymphoma
Journal of Leukemia & Lymphoma 2008;17(4):312-315
Ten years had passed for the molecular targeted therapy since approval by the U.S.Food and Drug Administration of the first monoclonal antibody-Rituximab,for the treatment of the B-cell non-Hodgkin's lymphomas with positive CD20- The targeting therapy,which may be a promising approach in the future,has significantly improved the patients'qualities of lives and prognosis because it has higher selectivity and less adverse effects than current chemotherapy and radiotherapy.In the past decade,with the fast development of novel targeting drugs and extension of therapeutic fields,the limitations associated with the targeted treatments were received attentions.
9.Syk and VEGF-C in breast cancer's expression with lymph node metastasis
Chinese Journal of Immunology 2014;(5):681-683
Objective:To explore the relationship of Syk and VEGF-C expression in breast cancer with lymph node metastasis . Methods:The expression of Syk and VEGF-C in 40 cases of breast cancer were determined using immunohistochemistry assay .Then, the positive rates of Syk and VEGF-C were compared with lymph node metastasis .Results:The expression rate of VEGF-C and Syk in breast cancer was respectively 77.5%(31/40), 37.5%(15/40).VEGF-C protein expression was not significant related with the tumor diameter (P>0.05) and histological grade (P>0.05), but was significantly associated with lymph node metastasis (P<0.05).Syk protein expression was not significant related with tumor diameter (P>0.05) and the histological grade(P>0.05), and was associated with lymph node metastasis (P<0.05).The difference of Syk and VEGF-C had statistics significance(P<0.05).Con-clusion:Syk and VEGF-C involved in the lymphatic invasion and metastasis , may be an important indicator of prognosis .
10.Design and implementation of temperature control system of high fever
Yongshou ZHANG ; Xiaochen ZHAO
China Medical Equipment 2013;(11):35-36
Objective: To cool down the implementation of field training injury cold and heat function of electric control part. Methods:To design of peripheral control circuit, the use of STM32 microcontroller software compiled program, temperature control function of the whole device. Results: Though the program running, it realized the function of temperature control device. Conclusion:STM32 MCU has powerful functions, low price, simple use, convenient development advantages, suitable for use in other medical equipment electrical control part.