Objective To study the distribution rule of syndrome factors in each diagnosis and staging of colorectal cancer.to Analyze the relationship between the syndrome factors and the clinical presentations of colorectal cancer,and then to provide a basis for further studying of the distribution and combination rule of syndrome factors in colorectal cancer.Methods The clinical data of patients with colorectal cancer was collected from Jiangsu Province Hospital of Traditional Chinese Medicine 2011.1-2011.12.According to the related standard,the spleen,large intestine,kidney,liver,qi deficiency,qi stagnation,wet,heat,blood stasis,poison,yang deficiency,yin deficiency,and blood deficiency altogether 13 common syndrome factors of colorectal cancer were selected.Retrospective study method was adopted to study the distribution of syndrome factors.And SPSS 17.0 statistical software was used to analyze the relationship between the syndrome factors and the clinical presentations of colorectal cancer.Results 6 clinical presentations include loose stool had a relationship with syndrome factor of liver; 7 clinical presentations include dark tongue had a relationship with syndrome factor of spleen; 4 clinical presentations include blood stool had a relationship with syndrome factor of large intestine; 8 clinical presentations include emaciation had a relationship with syndrome factor of kidney; 6 clinical presentations include tired with qi deficiency; red tongue with wet syndrome factor; 2 clinical presentations include dark tongue had a relationship with blood stasis syndrome factor,8 clinical presentations include pantothenic acid had a relationship with qi stagnation syndrome factor; 10 clinical presentations include pale tongue had a relationship with blood deficiency syndrome factor; red tongue had a relationship with heat syndrome factor; unsmooth pulse had a relationship with poison syndrome factor.Conclusions The syndrome factors of qi deficiency,spleen and qi stagnation are more common in colorectal cancer.11 in 13 syndrome factors have several relative clinical presentations.But the diagnosis of syndrome factor based on clinical presentations need further study.

Objective To analyze the polymorphism of excision repair cross-completion gene 1(ERCC1) in colorectal cancer pa-tients ,and to provide guidance for personalized therapy of colorectal cancer .Methods The polymorphism of ERCC1 in 259 patients with colorectal cancer was detected by PCR .Results The genotype of ERCC1 was mainly C/C(55 .71% ) in male patients ,and then C/T(37 .86% ) ,the genotype of T/T accounted for 6 .43% .The genotype of ERCC1 was also mainly C/C(59 .66% ) in female pa-tients ,and then C/T(36 .97% ) ,the genotype of T/T accounted for 3 .36% .The genotype was mainly C/C(51 .72% ) aged 25 to 44 patients ,and then C/T(41 .38% ) ,the genotype of T/T accounted for 6 .90% .The genotype was mainly C/C(57 .95% ) aged more than 44 to 59 patients ,and then C/T (40 .91% ) ,the genotype of T/T accounted for 1 .14% .The genotype was mainly C/C (58 .45% ) aged more than 59 patients ,and then C/T(34 .51% ) ,the genotype of T/T accounted for 7 .04% .Conclusion The poly-morphism of ERCC1 is mainly C/C in colorectal cancer patients .

Objective:To evaluate the effects of different nutritional supports in gastric cancer patients undergoing radical resection.Methods:Sixty patients with gastric cancer were randomly divided into three groups: parenteral nutrition(PN)group,enteral nutrition(EN) group and parenteral nutrition combined with enteral nutrition(PN-EN) group.The rate of complication, recovery time of the gut function,average post-operative hospital stay,changes of liver function,levels of blood glucose,serum albumin,prealbumin and transferrin,levels of nitrogen balance and change of body weight were observed in the three groups.The therapeutic effects of post-operational nutritional support were studied.Results:There are no significant difference in the rate of complication,average post-operative hospital stay,changes of liver function and level of blood glucose.The recovery time of the gut function in EN group was shorter than that in PN and PN-EN groups(P

Objective To develop a kind of system of simulation and training on ECG for studying ,training and assessing of biomedical engineer. Methods The simulation training system was designed based on PC. In the hardware system, ADuC848 SCM was adopted as the primary controller, QuickStart exploration platform was used to develop firmware, and intelligent assessing system was explored by C++ Builder. Results Biomedical Engineer could be trained, checked and evaluated by the system. Conclusion The system, combining practice and examination, pays attention to basic skill training and thus improves studying efficiency.

Version 2015 of the National Comprehensive Cancer Network (NCCN) Guidelines for Uterine Neoplasms uses the 2009 International Federation of Gynecology and Obstetrics (FIGO) staging system.These NCCN guidelines divide pure endnmetrioid cancers into three categories to delineate treatment:(1) disease limited to the uterus;(2) cervical involvement;(3) extrauterinc disease.Surgery is recommended for medically operable patients.Continuous progestin-based therapy may be considered for highly selected patients with stage IA disease who wish to preserve their fertility.Preoperative chemotherapy can be considered if extrauterine disease is suspected.Factors that may influence the decision regarding adjuvant therapy include lymph vascular space invasion (LVSI),patient age,tumor volume,and lower uterine segment or surface cervical glandular involvement.When administering adjuvant radiotherapy,it should be initiated as soon as the vaginal cuff has healed,no later than 12 weeks after surgery.

Bladder cancer stem cells may give the cause of the recurrence and metastasis of bladder cancer patients,and CD47 mediated the suppress of cytophagy maybe the important mechanism of cancerous cells' immunologic escape.It is practical to isolate bladder cancer stem cells and cure the bladder cancer by targeting the CD47.In this paper,the authors will address the progress of bladder cancer stem cells and CD47 as therapeutic target.

Objective To study the clinical and imaging characteristics as well as cerebrospinal fluid chan-gea(CSF) of spontaneous intracranial hypotensian syndrome (SIHS).Methods The clinical characteristics, CSF and imaging data of 13 patients diagnosed as SIHS were retrospectively analyzed.Results All the 13 patients had orthostatic headache accompaning one or more numerous symptoms including nausea, vomiting, dizziness, diplopia and neck stiffness.All the patients had low CSF pressure,which was below 60 mm H2O and high CSF protein was in 5 patients, 8 had increased white cell counts and 9 had increased red cells counts;CT was performed in all patients.On CT scan the subdural effusion or small ventricles were compressed in 4 patients.MRI typically revealed diffused pachymeningeal enhancement in 2 patients;All the patients experienced relief of symptoms through conventional treatment.Conclusion Orthostatic headache is the most typical symptom in spontaneous intracranial hypotension syndrome and diffused pachymeuingeal enhancement is the most common imaging manifestation, and CSF hypovol-emia is the basis of pathophysiology of spontaneous intracranial hypotension syndrome.

Objective To investigate the influence of early postoperative enteral nutrition on the immunologic function and inci-sion infection in the patients with colorectal cancer .Methods 81 postoperative cases of colorectal cancer were randomly divided into the early parenteral nutrition(41 cases) ,and the early enteral nutrition(40 cases) by the random number table method .The anal ex-haust time ,ambulation time and occurrence situation of incision infection ,etc .were compared between the two groups ,and the im-munological indexes changes were also compared .Results Postoperative anal exhaust time ,bed activity time and the occurrence rate of incision infection in the early enteral nutrition group were significantly lower than those in the early parenteral nutrition group (P<0 .05);Th1/Th2 and lymphocyte count in the early enteral nutrition group were significantly higher than those in the early parenteral nutrition group(P<0 .05) .Conclusion The early postoperative enteral nutrition support in the patients with colorectal cancer can effectively improve the body's immune function and is an ideal method of nutritional support .

Objective To analyse the effect of hedyotisdiffusa on expressions of apoptosis related protein Fas , caspase3 and caspase7 in Renca renal cell carcinoma of model mice.Methods One hundred and twenty BALB/C male mice were randomly divided into normal control group, model control group, interleukin group, hedyotisdiffusa group, 30 mice in each group, half male and female.Excepted for normal control group , renal cell carcinoma models were established in the other groups , and were given corresponding drug treatment.The tumor size and weight , and the tumor inhibition rate of all mice were observed, and the expression levels of Fas,FasL,caspase3 and caspase7 were detected.Results Compared with model control group, the tumor size and weight were lower , the tumor inhibition rate were higher , the positive expression rates and protein levels of Fas were higher , the positive expression rates and protein levels of FasL were lower, the positive expression rates and expression levels of Caspase3,Caspase7 protein were higher in the mice of interleukin group and hedyotisdiffusa group, all with significant differences ( P<0.05 ).The above indicators in hedyotisdiffusa group were significant improved compared with interleukin group (P<0.05).Conclusion The hedyotisdiffusa can effectively promote the expressions of apoptosis related protein Fas,caspase3 and caspase7 in renal cell carcinoma of model mice, inhibit the expression of FasL protein, improve the tumor suppression rate.

Chemotherapy, molecular targeted therapy, and hormonal therapy are essential components of medical oncology. Al-though cancer patients significantly benefit from the emergence of various new anticancer drugs, none of these treatments can directly address drug resistance. Radiation therapy is one of the three conventional cancer treatment methods. Nearly two-thirds of cancer pa-tients accept radiation therapy during treatment. However, radiation resistance is a significant barrier affecting the therapeutic effect of this procedure. Epithelial–mesenchymal transition (EMT) is a biologic process that enables a polarized epithelial cell to undergo multi-ple biochemical changes. These changes enable the cell to assume the functions of a mesenchymal cell phenotype. These functions have been extensively studied and are related to embryogenesis, tumor invasiveness, and metastasis. In recent years, increasing evidence sug-gests that EMT is closely linked with tumor treatment resistance. The study of the relation between EMT and tumor treatment resistance is expected to contribute to the prevention of drug resistance and radiation resistance and thus improve treatment efficacy to provide benefit to cancer patients. This article explores this issue.