Hospital Information System(HIS) contributes a lot to the management of the hospital with the personnel flow,the material flow,the fund flow and the information flow well-regulated.The construction of HIS has to be based on general scheme,and then the sub-systems are established separately,at last all sub-systems are integrated to form a system,that is HIS,to realize the modernization of the hospital management.

Acupuncture Therapy ; Female ; Humans ; Middle Aged ; Neuromyelitis Optica ; physiopathology ; therapy ; Vision, Ocular

OBJECTIVE:To optimize the formulation parameters of poly1,3-bis(p-carboxyphenoxy) propane-sebacic acid (P(CPP∶SA)) microsphere and evaluate its drug release performance in vitro. METHODS: The paclitaxel microspheres were prepared by single emulsion method,and the effects of the factors such as the stirring speed (A),P(CPP∶SA) concentration (B),emulsifier polyvinyl alcohol (PVA) concentration (C) on encapsulation efficiency were evaluated by orthogonal test. The surface morphology of the prepared microsphere was observed and its drug release performance in vitro was evaluated. RESULTS: The optimal formulation of the microsphere obtained was as follows: A was 4 000 r?min-1,B was 80 mg?mL-1 and C was 1%,respectively. The morphology of microspheres was round and intact. The encapsulation efficiency of paclitaxel was up to above 90%. The sustained release duration was 30 days with an accumulative release rate of over 80%. CONCLUSION: Paclitaxel microspheres prepared by optimal formula display a high encapsulation efficiency and satisfactory sustained-release pattern.

In recent years,scientific reports say that ApoE genotypes not only influence lipid metabolism but also affect bone metabolism through vitamin K. Primary osteoporosis is mainly regulated by genes and the interaction of genes and environmental factors also affects primary osteoporosis. This review focused on the mechanism of the influence of ApoE gene on bone mineral density and interaction of ApoE gene and environment factors in the determination of primary osteoporosis.

This study explores the association between physician-patient communication and healthcare service quality,and relevant factors.The physician-patient communication belongs to medical behaviors,and plays a key role in the improvement of physician-patient relationship and the overall healthcare service quality.The consults of physician-patient communication were affected by many factors including physicians' attitude,and usage of words and behaviors,in which the positive attitude and behaviors are key solution to the improvement physician-patient relationship.Therefore the urgent matters are to strengthen standardized management of physician-patient communication,and set up related regulations and effective measure.

Acupuncture Therapy ; Adult ; Alcoholism ; therapy ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged ; Peripheral Nervous System Diseases ; therapy

A case of mandible plasma cell myeloma is reported.Plasma cell myeloma is a monoclonal neoplastic proliferation of plasma cells of bone-marrow derivation,usually multi-centric but jaw bones are rarely involved.The treatment requires precise pathological diagno-sis.The prognosis of solitary jaw bone lesions can be good after treatment.

Objective To detect the methylation status of CDH1 3 gene promoter in colon cancer by using methylation-specific polymerase chain reaction(MSP)technique.Method The tissue specimens from 32 cases of colon cancer(observation group),and 12 cases of normal colon tissues(control group)were examined,the methylation of CDH13 gene promoter was detected by MSP.Result The methylation of CDH13 gene promoter was detected in 19 cases(59.4％,19/32)in observation group,1 case(8.3 ％,1 / 12)in control group,there was statistical significance between two groups(P =0.002).Conclusion Frequency of the methylation of CDH13 gene promoter is apparently higher in colon cancer tissues than that in normal colon tissues,it reveals that CDH13 gene promoter may contribute significantly to the development of colon cancer.

Th17 cells have recently emerged as a third independent helper T(Th) cell subset that is different from the classical Th1 and Th2 cells.Th17 cells can specifically secrete IL-17 and play an important role in tumorigenesis and metastasis.In this article, we review the origin and differentiation regulation of Th17 cells, the relationship between IL-17 and tumor microenvironment, angiogenesis and metastasis, and try to provide a new direction for the diagnosis and treatment of tumor.

Objective:To explore the relationship between Jiegu pastes and blood biochemical indices and the expression of cal-catonin gene related peptide( CGRP) in the process of fracture healing. Methods: The tibial fracture model of rats was established, and the rats were randomly divided into five groups:the blank control group, model control group, positive control group, Jiegu paste at low dose group ( L, 1 g·ml-1 , calculated by raw materials) and at high dose group ( H, 2 g·ml-1 , calculated by raw materials) with 60 ones in each. The blank control group and the model control group were given 2 ml saline, the positive control group was given 2 ml concentrated dipsacus bone mixture, and Jiegu paste L group and H group was given 2 ml concentrated solution at low concentra-tion and high concentration, respectively, and all the groups were with the following regimen: ig,qd, for 28 days. The blood samples and callus specimens were obtained on the 7th, 14th, 21st and 28th day after fracture. Blood biochemical indices were detected, and HE staining and immunohistochemical staining were performed. Results: Compared with those in the model control group, the serum calcium and phosphorus ion concentration in Jiegu paste H group significantly increased on the 14th and 21st day, and the serum AKP significantly increased on the 14th and 28th day (P<0. 05). The expression of CGRP in Jiegu paste H group was significantly higher than that in the control group (P<0. 05). There were no significant differences between H group and the positive control group (P>0. 05). Conclusion:Jiegu paste can achieve the purpose of promoting fracture healing by improving the activity of serum AKP, in-creasing the concentration of calcium and phosphorus and regulating the activity of neuropeptide CGRP.