1.122 Cases Analyses of Preeclampsia Caused to Preterm Labor
Chinese Journal of Perinatal Medicine 2003;0(06):-
ObjectiveTo investigate the outcomes of mother a nd baby smaller than 37 gestational age caused by preeclampsia. Method sThe data for 122 preterm birth that was single pregnancy with preecla mpsia in our hospital from January 1993 to December 2002 were collected. The pri nciple of diagnosis and treatment, the outcomes were analyzed retrospectively. T he 122 pregnant women were divided into 3 groups according to their gestational age, more than 28 weeks and smaller than 31 +6 weeks was the first group (28 cases), more than 32 weeks and smaller than 33 +6 weeks was the second grou p (26 cases), more than 34 weeks and smaller than 36 +6 weeks was the thir d group (68 cases). The data were statisted with SAS software.Results The earlier the pregnancy-induced hypertension happened, the earlier the preeclampsia occured, the mean time was 14 03 d, 16 85 d,22 22 d, respect ively, (P0.05), the outcomes of mothers were good. Increasing the gestational age under the cond ition that the occurrene of comptications was not increased, 60 64% pregnant wo men accepted the treatment of improving the maturity of fetal lung. There were n o differences among the three groups at the morbidity of perinatal SGA, intracra nial hemorrhage (P 0.05) .ConclusionWe could improve the outcomes of pret erm birth caused by preeclampsia by enhancing the perinatal care, treating and t erminating pregnancy activey Increasing the gestational age, improving the matur ity of fetal lung would decrease the morbidity of severe RDS and improve the pe rinatal outcome effectively.
2.Effects of tanshinone IIA on cardiac monophasic action potential in acute cerebral ischemia rats
Chinese Journal of Pathophysiology 2016;32(12):2291-2294
AIM:To investigate the effects of tanshinone IIA ( Tan) on cardiac action potential in rats with a-cute cerebral ischemia (ACI).METHODS:ACI was established in rats accordingly .Animals were divided into 3 groups:sham group, ACI group, and ACI with Tan treatment group .The defect of neural function in each group was graded , elec-trocardiogram was measured , monophasic action potential was recorded , and the levels of cardiac troponin I ( cTnI ) and creatine kinase-MB ( CK-MB) were examined by commercially available kits .RESULTS:Compared with ACI group , Tan significantly decreased the scores of the defect of neural function , reduced the incidence and duration of the abnormalities in electrocardiogram , prolonged the effective refractory period , action potential duration at 50%repolarization and action po-tential duration at 90%repolarization, and inhibited the elevation of cTnI and CK-MB levels.CONCLUSION:Tan main-tains a stable heart rhythm in ACI rats , which may be related to its protective effect on ischemic myocardium .
4.The Developing Status of Traditional Chinese Medical Education in Australian Comprehensive Universities
World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(1):171-177
The education of traditional Chinese medicine appeared in the 1990s in Australia and has been under the supervision of Australian Health Practitioner Regulation Agency (AHPRA) since 2011.Six institutions,including three comprehensive universities—University of Technology Sydney,Western Sydney University and Royal Melbourne Institute of Technology University,have set up programs and offered the bachelor and the master of traditional Chinese medicine so far.This paper chiefly introduced and analyzed the current education status,size and characteristics of traditional Chinese medicine of the three universities with the provision of a reference for the international development and cooperation in traditional Chinese medical education with high quality.
5.Correlative analysis of free amino acid changes in plasma and brain in hepatic encephalopathy of fulminant hepatic failure in rats
Xianming CHEN ; Yuauchang ZHAO
Chinese Journal of Pathophysiology 1986;0(03):-
Changes of free amino acids in plasma and brain of rats with fulminanthepatic failure were measured with a Beckman 6300 amino acid analyzer.Results indicat-ed that as hepatic encephalopathy developed, concentrations of almost all amino acids inplasma and brain were increased.The levels of most amino acids in brain showed no cor-relation with their changes in the plasma.However,changes of concentrations of theseamino acids in brain that were related to the development of hepatic encephalopathy wereclosely correlated with their concentrations in plasma.Not any correlations between chan-ges of any amino acids in plasma and brain were found in normal control rats.Theseresults suggested that amino acid transport mechanisms appeared to be specific in the blo-cd-brain barrier during fulminant hepatic failure,a phenomenon that could contribute tothe neural disturbance of hepatic encephalopathy.
6.Side effects of psychotherapy
Chinese Mental Health Journal 2017;31(1):72-76
Psychotherapy is a kind of medical treatments based on interpersonal interaction that is highly context-dependent.While psychotherapy is an important treatment in clinical work and its effectness has been confirmed with wide practical application,its adverse effects has received little attention.This article will review the literaturesand discuss the possible side effects and relatedfactors of psychotherapy.
7.Comparative study of the injury to hepatocarcinoma and normal liver tissues following ischemia and reperfusion
Chinese Journal of General Surgery 2001;0(07):-
ObjectiveTo compare the injury to hepatocarcinoma and normal liver tissues following ischemia and reperfusion. MethodsThe hepatocarcinoma(HC) models were established by injectin of VX2 tumor (tissue) suspension fluid into the left-middle lobe of liver of rabbits. After the models were established, the models left hepatic vessels were occluded for 60 minus, then followed by various intervals of reperfusion, and the levels of superoxide dismutase (SOD) and malondialdehyde (MDA) were measured, and apoptotic (changes) in the hepatocarcinoma and normal hepatic tissues were observed by means of HE staining and TUNEL method. ResultsThe concentration of SOD decreased significantly in hepatocarcinoma tissue and reached the lowest point at 1h after ischemia and reperfusion (64.594.97NU/mgprot), then gradually rebounded, but, at 7d after reperfusion, it still retained at a lower level(121.126.88NU/mgprot) than that before reperfusion. In contrast with normal liver tissues,the concentration of MDA decreased in the hepatocarcinoma tissues following ischemia and reperfusion, the changs of MDA were similar to SOD. The apoptotic cells in hepatocarcinoma tissues increased to the highest point at 1 day following reperfusion, but 7d after reperfusion, the number of positive cells were more than before reperfusion, and the apoptotic rate was higher in (hepatocarcinoma) tissues compared with the normal liver tissues. ConclusionsIn comparison with normal liver tissue, hepatocarcinoma tissue is more suscepible to the injury of ischemia and reperfusion.
8.EAST/SeSAME syndrome and functional expression of inward rectifier potassium channel Kir4.1 in the inner ear.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(14):1318-1322
Inwardly rectifying potassium (Kir) channels exhibit an asymmetrical conductance at hyperpolarization (high conductance) compared to depolarization (low conductance). The KCNJ10 gene which encodes an inwardly rectifying K+ channel Kir4.1 subunit plays an essential role in the inner ear and hearing. Mutations or deficiency of KCNJ10 can cause hearing loss with epilepsy, ataxia, sensorineural deafness, and renal tubulopathy (EAST) or SeSAME (seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance) syndromes. In this review, we mainly focus on the expression and function of Kir4.1 channels in the inner ear and mutation-induced EAST/SeSAME syndromes to provide insight for understanding the pathogenesis of deafness induced by KCNJ10 deficiency.
Deafness
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genetics
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metabolism
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Ear, Inner
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metabolism
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Hearing Loss, Sensorineural
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genetics
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metabolism
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Humans
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Intellectual Disability
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genetics
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metabolism
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Mutation
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Potassium Channels, Inwardly Rectifying
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genetics
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metabolism
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Seizures
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genetics
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metabolism
9.Progress in mechanism of insulin resistance related to intrauterine growth retardation
International Journal of Pediatrics 2010;37(2):125-127
Fetal origins of adult disease,the thrifty phenotype hypothesis, nutritional programming,metabolic programming indicate that nutrition in early life is important.Epidemiological survey demonstrates that insulin resistance is relataed to intrauterine growth retardation,but the exact mechanism is indefinite.This article is about the influence of intrauterine growth retardation to the structure and function of pancreas,and the genes that related to insulin resistance.
10.Clinical value of emergency gastroscopy in diagnosis and treatment for upper gastrointestinal hemorrhage
Chinese Journal of General Practitioners 2010;09(8):562-563
Emergency gastroscopy was performed for 146 patients with upper gastrointestinal hemorrhage admitted to Tieying Hospital, Beijing to identify causes of bleeding and establish diagnosis. One hundred and thirty-nine of them were cured with endoscopic treatment, but two failed so to change to surgical operation. It suggested that early gastroscopy is a convenient, easy and safe method in diagnosis and treatment of upper gastrointestinal hemorrhage.