Through a retrospective clinical analysis of 3160 cases of severe cranio cerebral injury ( SCCI ), the aim of this study is to explore effective treatments to increase cure rate for this injury. The causes and types of trauma, operation modalities,and prognosis were reviewed. The main causes resulting in SCCI were traffic accidents and fall from a height. The main types of SCCI were subdural, extradural and multiple intracranial hematomas. The main signs and symptoms were unconsciousness, pyramidal signs and pupil changes. The rate of cure and improvement was 73 6%. The mortality rate was 19 4%. Early diagnosis and timely operation, maintenance of patency of the respiratory tract, brain protection during operation, and competent ICU care after operation were important measure to achieve good recovery of SCCI patients.