Objective To improve the data disaster response capacity of hospital information system and protect the safety of hospital data. Methods The data for disaster-related technical characteristics was comparatively analyzed. Results The variety of disaster recovery technologies has the advantages and disadvantages to choose the best program. Conclusion Only the establishment of disaster recovery applications can solve the data security and protect the hospital's business continuity.

Ovbective To study the protective effects of 17?-estradiol on isolated ischemic rat hearts in a modified Langendorff model. Methods Thirty rats performed bilateral ovariectomies were divided equally into three groups at random. A three-phase protocol was performed: (1) 15-minutes preperfusion,(2) 30-minutes global ischemia,(3) 30-minutes reperfusion. Treatment with 0.1% DMSO (group D) and 5 ?mol/L 17?-estradiol+0.1% DMSO (group E) dissolved in K-H buffer was perfused from sixth minutes of reperfusion. Only K-H was perfused in the ischemia-reperfusion group (group I-R). The left ventricular pressure (LVP) and it's first derivative (?dp/dt max ) and coronary flow (CF) were recorded at the 15th minute of preperfusion and the 30th minute of reperfusion. Creatin phosphokinase (CPK) and lactic dehydrogenase (LDH) the coronary effluent,the content of malonaldehyde (MDA) and superoxide dismutase (SOD) activity of myocardium were measured at the 30th minute of reperfusion. Results After 30-minute reperfusion,restoration of heart function of group E treated with 17?-estradiol were better than that of group I-R and group D,with a higher coronary flow,and a lower CPK and LDH level (P

Changes in respiratory function before and after CPB in 40 children with state of left-to-right shunt of VSD were studied. Among the cases, 20 of them were with pulmonary hypertension (PH group ) and 20 without PH (control group). Before CPB, resist ante of inspira tion (RI) and resistance of expiration (RE)in PH group (23.87?7.53,42.98?12.1) were significantly higher than those of control group(RI 17.95?7.53,RE 34.95?5.13);compliance of lung-thorax(CLT) in PH group(11.58?4.87) was significantly lower than that of control group(14.32?1.99). After CPB. both RI (30.94?11.89) and RE(46.43?9.9) in PH group were greatly higher than those in control group (28.00?9.29,46.43?9.9);CLT (10.98?4.6) was lower than that of control group (12.3?2.68). In PH group,the PaO_2 decreased and the magnitude of A-aDO2 increased much more than those in control group. The results suggest that respiratory function in the children with PH might not be improved immediately after CPB separation.

Objective:To investigate the training of writing research paper for graduate students majoring in medical imaging, therefore improving international academic communication. Methods: Analyzing the problems existed in English paper writing for the graduate students majoring in medical imaging. According to the feature of English paper writing in the field of medical imaging, the new teaching model was used and the problem-based-learning method was introduced.Results: The new training model of English research paper writing is practical and helpful for graduate students majoring in medical imaging to improve their writing skill and research ability.Conclusion: The training of English research paper writing is efficient for graduate students majoring in medical imaging. The training process can lay good foundation for their future research careers.

Objective To discuss the relationship between clinical pathway management and semi-structured electronic medical record(EMR),and explore the effects of EMR on hospital information system and its management quality.Methods EMR was used in combination with quality management and clinical pathway management.The relationship between clinical pathway management and semi-structured electronic medical record(EMR) was researched.Results Semi-structured EMR can increase the clinical pathway managerment and improve the clinical quality of management,the competitiveness of hospital can be upgraded.Conclusion Hospital should widely develop semi-structured EMR and promote the clinical pathway managerment in the future.

Objective To investigate the clinical outcome of fixation and autograft through the pedicle of fractured vertebrae for thoracolumbar burst fracture. Methods 138 cases with thoracolumbar burst fracture were retrospectively analyzed. 30 cases (group A) accepted 4 pedicle screw fixation with autogrft, and other 108 cases (group B) accepted internal fixation through the pedicle of fractured vertebrae with autogrft. All the cases were followed up for 22~72 months. Results The fractured vertebral height and Cobb's angle recovered and the neurological function improved after treatment in both groups (P<0.05), but there was no significant difference between 2 groups. There was significant difference in Visual Analogue Score for back pain (P<0.05). Conclusion Vertebral pedicle screw fixation with transpedicular autograft is an effective operation for thoracolumbar burst fracture, especially on back pain.

Objective To investigate cell-killing and bystander effects on gallbladder cancer (GBC-SD) cells transferred with double suicide genes (CD and HSV-tk). Methods CD and HSV-tk genes were transfected into PA317 cells using lipofectamine. GBC-SD cells were infected with viral supernatant. GBC-SD/CD+tk cells were treated with 5-FC and/or GCV. GBC-SD/CD+tk and GBC-SD were inoculated subcutaneously into the nude mice respectively and treated with GCV and 5-FC for 21 days. Results The killing effect of 5-FC and GCV in combination on GBC-SD/CD+tk cells is more effective than using 5-FC or GCV alone. The local bystander effect is significant while the distant bystander effect was not obvious. Conclusion The cell-killing efficacy of chemotherapy on GBC-SD transfected with double suicide gene was significantly increased, and the bystander effect was obvious.

Objective To study the value of dual-source CT(DSCT)in assessing aortic mechanical valve with 3D cardiovascular imaging technique.Methods Thirty-four patients with mechanical aortic valve transplantation were enrolled.Nineteen cases transplanted with On-x valve and 15 cases with St jude valre.CT scan was performed in all 34 patients and MRI scan in 30 patients.The CT imaging quality of On-x valve with St jude valve was compared by two independent samples Wilcoxon rank test.Two independent sampies test was used to compare tlle valve angle in the two kinds of valve and also in the same group.The relative functional index of left ventricle in CT and MR analysis by paired-samples t Test. Results The image quality was dirided into three grades.Six hundred and eighty phases in all 34 patients.which included 391 phases with grade 1,171 phases with grade 2 and 118 phases with grade 3.There were no significant different between two kinds of mechanical valve in image quality(image quality of grade 1:Z=-1.084,P=0.286;grade 2:Z=-0.088,P=0.945;grad 3:Z=-1.045,P=0.319).The mean bileaflet angle of 34 cases was 82.0°±4.4°in completely opening and 34.5°±5.7°in completely closing.The mean radian gradient over openess and closure was 47.5°±7.5°.The radian gradient of St iude group(55.0°±1.8°)was obviously larger than On-x group(41.5°±4.1°)(t=-11.732,P=0.000).But,there were no significant difference between dual-source CT and 1.5 T MR when evaluate the left ventrical fuction,including EF[MR.EF(57.2-1-2.8)%,CT-EF(57.9±2.8)%,f:-0.496,P=0.623],EDV[MR-EDV (121.6±9.1)ml,CT-EDV(132.9±11.2)ml,t=-1.198,P:0.240],ESV[MR-ESV(55.1±6.9)ml,CT-ESV(59.5±7.6)ml,t=-1.094,P=0.283],myocardium mass at ED[MR-Myo.mass (155.5 ±12.6)g,CT-Myo.mass(147.9±11.6)g,t=1.823,P=0.079]and CO[MR-CO(5.7±0.4)ml/min,CT-CO(5.9±0.5)ml/min,t=-3.211,P=0.775].Conclusions Dual source CT with 3D cardiovascular imaging technique is valuable and effective for evaluating aortic mechanical valve.The shape of the whole valve and movement of bileaflet reappears well.With the postprocessing software,it allows evaluating aortic mechanical valve function,reliable measurements of opening and closing leaflet angles and left ventrieal function.

Objective To investigate the diagnostic performance of stress cardiac magnetic resonance(CMR) for evaluating low-risk patients with suspected acute coronary syndrome(ACS).Methods Twenty-two patients with low risk of suspected ACS were prospectively and consecutively enrolled in this study.Diagnostic performance of stress CMR was compared with single-photon emission computed tomography(SPECT) for diagnosis of myocardial ischemia with coronary angiography (CAG) as the reference method.Results On the patient-based level analysis,the diagnostic performance of CMR for detection of ACS was sensitivity 93% and specificity 75%.The corresponding value of SPECT was 79%,63%.The area under the ROC (AUC) of CMR was 0.897, which was slightly superior to that of SPECT at 0.723 (P=0.19).On the per-vessel assessment, the diagnostic value of CMR was sensitivity 89%,specificity 87%, while the corresponding value of SPECT was 68%,83%.The AUC of CMR was 0.923,which was significantly higher than that of SPECT at 0.774 (P<0.05).Furthermore, the AUC of CMR was significantly superior to that of SPECT with AUC being 0.900 and 0.553 in the left anterior descending (LAD) vessels (P=0.009 6).Conclusion Stress perfusion CMR has excellent diagnostic performance in low risk ACS patients.Compared with SPECT,stress perfusion CMR performed better in the low-risk ACS populations.

Objective To investigate the feasibility of coronary CT angiography in single cardiac cycle and to analyze the image quality and radiation dose in patients with high heart rate(HR) using 256-row detector CT. Methods Ninety-two consecutive patients between October and November 2015 who were suspected coronary artery disease underwent coronary CT angiography(CCTA) were enrolled, which was performed with a 256-row detector CT(Revolution CT, GE Healthcare) using prospective ECG-triggered volume CCTA within a single cardiac cycle with snapshot freeze(SSF) technique. The patients were grouped by HR during CT scans: group A(80—89 bpm, n=56), group B(90—99 bpm, n=20), and group C(≥100 bpm, n=16). Image quality was compared before and after using SSF technique reconstructions in seventy-four patients. The image quality of coronary artery was evaluated blindly by 2 experienced radiologists using a four-point scale based on the 18-segment model according to the Society of Cardiovascular Computed Tomography guidelines. The differences in age, body mass index, heart rate and CT dose index volume,effective dose(ED) among the three groups were compared by using ANOVA analysis or Kruskal-Wallis test, the image quality and interpretability using χ2 test. Comparisons of image quality between standard and SSF were performed with paired Wilcoxon rank sum test. Kappa coefficient was used to test inter-observer agreement. Results A total of 1 065 coronary artery segments, 98.97%(1 054/1 065) met the requirements for diagnosis. No significant difference was found(χ2=1.274, P=0.563) for the diagnostic image quality of coronary artery segments among the 3 groups with 98.64%(651/660), 99.57%(232/233), 99.42%(171/172), respectively. Significant difference(χ2=68.811, P<0.05) was found for diagnostic image quality before and after using SSF with increase from 90.29%(772/855) to 99.44%(881/886). Image quality was improved with the use of SSF reconstructions and the diagnostic segments were also increased. The median of ED for group A, B and C was 2.03, 1.93, 2.37 mSv, respectively. There was no significant difference in ED among group A, B and group C(H=2.412,P>0.05). Conclusions Single cardiac cycle scan is feasibility for coronary CT angiography in patients with high heart rate using 256-row detector CT. This scan mode can maintain the diagnostic image quality with low radiation dose. SSF technique can improve the image quality.