1.Finite element model of artificial lumbar disc replacement
Hua WANG ; Kanghua LI ; Zhangyuan LIN
Chinese Journal of Tissue Engineering Research 2005;9(14):-
BACKGROUND: Artificial lumbar disc replacement is a novel approach to treat lumbar disc protrusion. But its theoreticalbasis needs further verification.OBJECTIVE:To establish finite element model of lumbar disc replacement for biomechanical studies.DESIGN: A single sample study taking the data of L4-5 three-dimensional infinite element model as object of research.SETTING: Orthopedic Department of Xiangya Hospital of SunYat-sen University.PARTICIPANTS: The trial was conducted in the Laboratory of the Orthopedic Department of Xiangya Hospital from December 2003 through August 2004. A healthy male volunteer served as simulation. His T12-S1 underwent continuous CT scanning. There were altogether 264 images with 2 mm inthickness each. Three-dimensional images were reconstructed every 15° in order to obtain the data for three-dimensional model.METHODS: The CT images and human anatomical data were processed by 3DSMAX software to establish three-dimensional L4-5 model of normal Chinese males. It was then transformed to finite element model after processed by SAP2000 software together with Charite SB Ⅲ disc prosthesis model.MAIN OUTCOME MEASURES: The three-dimensional model and finiteelement model of lumbar spine were successfully established.RESULTS: The finite element model of Charite SB Ⅲ disc replacement in L4_5 spine was established. The total nodes were 2542 and there were 1924Solid units, 592 Area units and 50 link units.CONCLUSION:The finite element model of artificial disc replacement can be established by CT scanning, digital processor and computer aideddesign,and used for further study on spinal biomechanics.
2.Correlation between job burnout and self-efficacy ,job satisfaction in bank staff
Juan LI ; Lin ZHAO ; Zhangyuan WANG ; Junlin MU ; Zhaohui ZHANG
Journal of Xinxiang Medical College 2017;34(9):827-829
Objective To understand the job burnout status of bank staff and analyse the relationship between job burnout and self-efficacy,job satisfaction.Methods The job burnout,self-efficacy and job satisfaction of 8 942 bank staff was surveyed by Maslach burnout inventory-general survey(MBI-GS),general self-efficacy scale (GSES) and job satisfaction scale (JSS) respectively.Results A total of 8 942 questionnaires were issued and 7 486 valid questionnaires were returned.The score of self-efficacy in male was significantly higher than that in the female(P <0.05).There was no significant difference in job satisfaction score between male and female(P > 0.05).The score of emotional exhaustion (EE) in female was significantly higher than that in male,while the score of reduced personal accomplishment(RPA) was significantly lower than that in male (P < 0.05);there was no significant difference in depersonalization (DP) score between male and female (P > 0.05).The EE,DP and PAL scores of bank staff with post-graduate education were significantly lower than those with high school/secondary school and junior college/undergraduate (P < 0.05);the DP and PAL scores of bank staff with junior college/undergraduate were significantly lower than those with high school/secondary school(P < 0.05);there was no significant difference in EE score of bank staff between junior college/undergraduate and high school/secondary school(P > 0.05).The EE score of age > 50 years old bank staff was significantly lower than that of age < 30 years old,30-40 years old and 41-50 years old (P <0.05);there was no significant difference in EE score among age <30 years old,30-40 years old and 41-50 years old bank staff (P > 0.05).The DP score of 41-50 years old bank staff was significantly higher than that of age < 30 years old (P <0.05);there was no significant difference in DP score among age <30 years old,30-40 years old and 41-50 years old bank staff (P > 0.05).There was no significant difference in PAL score among all age groups (P > 0.05).The three dimensions of job burnout had significant negative correlation with self-efficacy and job satisfaction (P < 0.05).Conclusion Bank staff have a certain degree of job burnout.Age,sex,and education level maybe the influence factors of job burnout.Improvement of self-efficacy and job satisfaction may help to reduce the job burnout.
3.Total mesorectal excision with double mastomosis instruments in lower rectal carcinoma
Qingdong ZENG ; Lihong LU ; Lei WANG ; Zhangyuan LI
Chinese Journal of General Surgery 2000;0(11):-
ObjectiveTo determine the effect of total mesorectal excision with double anastomosis instruments(DAIs) in lower rectal carcinoma. MethodsFrom 1995 to 1998,57 cases of middle and lower segement rectal carcinoma were treated by total mesorectal excision with DAIs, and were followed for 3 years. Results No operative death and no anastomotic leakage were noted. Two patients suffered from anastomotic stenosis,but no dysuria and sexual dysfunction occurred. Local recurrence rate was 5.3%(3/57)in the follow-up period. ConclusionsTotal mesorectal excision with DAIs is not only an effective method to maintain pelvic organ function in lower rectal cancer, but also able to improve the living quality of patients and reduce local reccurence.
4.Wearable Automatic External Defibrillators.
Huajie LUO ; Zhangyuan LUO ; Xun JIN ; Leilei ZHANG ; Changjin WANG ; Wenzan ZHANG ; Quan TU
Chinese Journal of Medical Instrumentation 2015;39(6):391-394
Defibrillation is the most effective method of treating ventricular fibrillation(VF), this paper introduces wearable automatic external defibrillators based on embedded system which includes EGG measurements, bioelectrical impedance measurement, discharge defibrillation module, which can automatic identify VF signal, biphasic exponential waveform defibrillation discharge. After verified by animal tests, the device can realize EGG acquisition and automatic identification. After identifying the ventricular fibrillation signal, it can automatic defibrillate to abort ventricular fibrillation and to realize the cardiac electrical cardioversion.
Animals
;
Defibrillators
;
Electric Countershock
;
Electric Impedance
;
Equipment Design
;
Heart
;
Humans
;
Monitoring, Physiologic
;
instrumentation
;
Ventricular Fibrillation
;
therapy
5.Clinical value of combined detection of serological and biochemical test for Salmonellain
Xianmo WANG ; Zhangyuan YANG ; Liang MING ; Liangcai XIE ; Jinzhi LU ; Lin XIAO ; Yanlin LI
International Journal of Laboratory Medicine 2015;(11):1486-1487
Objective To explore the value of comprehensive biochemical and serological test in Salmonella clinical test .Methods A total of 95 cases of suspected salmonella infection with enteric fever were selected as subjects in this study from April 2013 to A‐pril 2014 ,and 48 cases randomly divided in research group ,47 cases in control group .Regular inspection was conducted in the con‐trol group ,comprehensive biochemical and serological test were conducted in the control group .Compared the results in the two groups .Results The salmonella detection rate in the research group was 93 .75% ,which was significant higher than 68 .09% in the control group (P< 0 .05) .Conclusion Combined detection of comprehensive biochemical and serology test could detect Salmonella effectively ,it is worthy of application and popularization in clinic .
6.Three-dimensional finite element analysis of the zygapophyseal joints following artificial lumbar disc replacement
Hua WANG ; Daqi XU ; Jianzhong HU ; Kanghua LI ; Zhangyuan LIN ; Guanghua LEI
Chinese Journal of Tissue Engineering Research 2010;14(26):4915-4919
BACKGROUND: With deepening of spinal biomechanics, artificial lumbar disc replacement is considered to be the optimal choice for treating degenerative lumbar disease. However, studies concerning biomechanics of artificial lumbar disc are insufficient. OBJECTIVE: To establish the three-dimensional (3-D) finite element model of artificial lumbar disc replacement and to explore the effects of artificial lumbar disc replacement on zygapophyseal joints using biomechanical analysis. METHODS: Based on normal 3-D finite element model of lumbar motion segment, L4-5 intervertebral disc, superior and inferior endplates were removed, and then, the model of SB-Charite Ⅲ disc prosthesis was added, which remained annular fibrosus and ligaments at L4-5 intervertebral space. Thus, 3-D finite element model of L4-5 segments artificial lumbar disc replacement was constructed. Biomechanical analysis of this model was processed under axial load, forward flexion, lateral bending or posterior extension moments. The stress data were contrasted with the normal 3-D finite element model of artificial disc replacement. RESULTS AND CONCLUSION: After artificial lumbar disc replacement, the data of biomechanical analysis indicated: ①There was no significant differences between the zygapophyseal joint and normal segment of stress under axial load (P > 0.01).②Compared with normal segment, the stress of anterior, posterior of upper and lower vertebral body and bilateral zygapophyseal joint had no obviously difference under forward flexion and posterior extension moments (P > 0.01). ③The stress differences between the both sides of upper and lower vertebral body and bilateral zygapophyseal joint were not significant under lateral bending moment (P > 0.01). Artificial lumbar disc replacement can keep the stress of motion segment at normal level, which can meet the needs of spinal functional reestablishment.
7.Multiple of biochemical index test in the diagnosis of fatty liver
Xianmo WANG ; Zhangyuan YANG ; Liang MING ; Liangcai XIE ; Jinzhi LU ; Lin XIAO ; Yanlin LI
International Journal of Laboratory Medicine 2015;(12):1651-1652
Objective To explore a variety of levels of serum marker test applications in the diagnosis of fatty liver .Methods Data were randomly selected from April 2013 to April 2014 for treatment of patients with fatty liver hospital 45 cases ,set the study group ,choose the same period in healthy volunteers to undergo a medical examination in our hospital 45 cases ,it was set to control group ,two groups of subjects were taking a variety of levels of serum markers tested .Comparison and analysis of two groups of subjects to detect a variety of levels of serum markers and positive case detection rate .Results The study group subjects ALT , AST ,TG ,TC index the average level of detection was higher than the control group ,statistically significant differences (P<0 .01);study group subjects ALT ,AST ,TG ,TC index the positive rates were 77 .78% ,93 .33% ,55 .56% ,46 .67% more than 8 .89% in the control group ,4 .44% ,15 .56% ,11 .11% higher ,statistically significant differences (P<0 .05);United biochemical indicator de‐tection of biochemical indicators of detection rate of fatty liver was obviously higher than that of single detection rate ,the difference was statistically significant (P<0 .05) .Conclusion Multiple levels of serum markers of fatty liver diagnostic test in higher detec‐tion rate .
8.Construction and efficiency analysis of prediction model for venous thromboembolism risk in the elderly after hip fracture.
Jiangnan PENG ; Haochen WANG ; Liang ZHANG ; Zhangyuan LIN
Journal of Central South University(Medical Sciences) 2021;46(2):142-148
OBJECTIVES:
To screen the risk factors for predicting venous thromboembolism (VTE) risk after hip fracture in the elderly, to establish a prediction model based on these factors, and to analyze its prediction efficacy.
METHODS:
A total of 52 hip fracture patients over 60 years old with VTE admitted to the Department of Orthopaedic Trauma, Xiangya Hospital, Central South University from March 2017 to April 2019 were selected as a thrombus group, and another 52 hip fracture patients over 60 years old without VTE were selected as a control group. The differences of hospitalization data and examination results between the 2 groups were compared. Logistic regression model was used to explore the influence of risk factors on VTE risk after hip fracture in the elderly and construct the prediction model based on these factors. The receiver operating characteristic curve was used to analyze the predictive effectiveness of model, Hosmer-lemeshow goodness of fit test was used to evaluate the fitting degree of prediction model.
RESULTS:
Univariate analysis showed that injury-admission interval, Caprini score, WBC count, platelet count, neutrophil count, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, systemic immune-inflammatory index (SII), and fibrinogen in the thrombus group were higher than those in the control group (all
CONCLUSIONS
SII, Caprini score, and injury-admission interval are independent predictors of VTE after hip fracture in the elderly. The prediction model based on these 3 factors has a good efficacy on the prediction of VTE risk, and could provide important reference for the prevention, management, and treatment of VTE after hip fracture in the elderly.
Aged
;
Hip Fractures/surgery*
;
Humans
;
Middle Aged
;
ROC Curve
;
Retrospective Studies
;
Risk Assessment
;
Risk Factors
;
Venous Thromboembolism/etiology*
9.Expert consensus on the accurate diagnosis and treatment of acetabular fractures based on three-column classification (version 2023)
Ruipeng ZHANG ; Hongmin CAI ; Shicai FAN ; Gang LYU ; Yan ZHUANG ; Chengla YI ; Xiaodong GUO ; Longpo ZHENG ; Xianzhong MA ; Hua CHEN ; Dahui SUN ; Guanglin WANG ; Qishi ZHOU ; Weixu LI ; Wei FENG ; Zhangyuan LIN ; Xiaodong QIN ; Jiandong WANG ; Zhanying SHI ; Lianxin LI ; Guangyao LIU ; Shuquan GUO ; Ming LI ; Jianzhong GUAN ; Yingze ZHANG ; Zhiyong HOU
Chinese Journal of Trauma 2023;39(10):865-875
Accurate classification of the acetabular injuries and appropriate treatment plan are great challenges for orthopedic surgeons because of the irregular anatomical structure of the acetabulum and aggregation of important vessels and nerves around it. Letournel-Judet classification system has been widely applied to classify acetabular fractures. However, there are several limitations, including incomplete inclusion of fracture types, difficulty in understanding and insufficient guidance for surgical treatment, etc. Serious complications such as traumatic arthritis are common due to wrong classification and diagnosis and improper selection of surgical strategy, which brings a heavy burden to the society and families. Three-column classification, based on anatomic characteristics, has advantages of containing more fracture types and being easy to understand, etc. To solve the problems existing in the diagnosis and treatment process based on Letournel-Judet classification, achieve accurate diagnosis and treatment of patients with acetabular fractures, and obtain satisfactory prognosis, the Orthopedic Trauma Emergency Center of Third Hospital of Hebei Medical University and the Trauma Orthopedic Branch of the Chinese Orthopedic Association organized experts from relevant fields to formulate the Expert consensus on the accurate diagnosis and treatment of acetabular fractures based on three-column classification ( version 2023) in terms of principles of evidence-based medicine. Based on the three-column classification, 15 recommendations were proposed, covering the diagnosis, treatment, complication prevention and management, etc, so as to provide reference for accurate diagnosis and treatment of acetabular fractures.