1.Finite element model of artificial lumbar disc replacement
Hua WANG ; Kanghua LI ; Zhangyuan LIN
Chinese Journal of Tissue Engineering Research 2005;9(14):-
BACKGROUND: Artificial lumbar disc replacement is a novel approach to treat lumbar disc protrusion. But its theoreticalbasis needs further verification.OBJECTIVE:To establish finite element model of lumbar disc replacement for biomechanical studies.DESIGN: A single sample study taking the data of L4-5 three-dimensional infinite element model as object of research.SETTING: Orthopedic Department of Xiangya Hospital of SunYat-sen University.PARTICIPANTS: The trial was conducted in the Laboratory of the Orthopedic Department of Xiangya Hospital from December 2003 through August 2004. A healthy male volunteer served as simulation. His T12-S1 underwent continuous CT scanning. There were altogether 264 images with 2 mm inthickness each. Three-dimensional images were reconstructed every 15° in order to obtain the data for three-dimensional model.METHODS: The CT images and human anatomical data were processed by 3DSMAX software to establish three-dimensional L4-5 model of normal Chinese males. It was then transformed to finite element model after processed by SAP2000 software together with Charite SB Ⅲ disc prosthesis model.MAIN OUTCOME MEASURES: The three-dimensional model and finiteelement model of lumbar spine were successfully established.RESULTS: The finite element model of Charite SB Ⅲ disc replacement in L4_5 spine was established. The total nodes were 2542 and there were 1924Solid units, 592 Area units and 50 link units.CONCLUSION:The finite element model of artificial disc replacement can be established by CT scanning, digital processor and computer aideddesign,and used for further study on spinal biomechanics.
2.Correlation between job burnout and self-efficacy ,job satisfaction in bank staff
Juan LI ; Lin ZHAO ; Zhangyuan WANG ; Junlin MU ; Zhaohui ZHANG
Journal of Xinxiang Medical College 2017;34(9):827-829
Objective To understand the job burnout status of bank staff and analyse the relationship between job burnout and self-efficacy,job satisfaction.Methods The job burnout,self-efficacy and job satisfaction of 8 942 bank staff was surveyed by Maslach burnout inventory-general survey(MBI-GS),general self-efficacy scale (GSES) and job satisfaction scale (JSS) respectively.Results A total of 8 942 questionnaires were issued and 7 486 valid questionnaires were returned.The score of self-efficacy in male was significantly higher than that in the female(P <0.05).There was no significant difference in job satisfaction score between male and female(P > 0.05).The score of emotional exhaustion (EE) in female was significantly higher than that in male,while the score of reduced personal accomplishment(RPA) was significantly lower than that in male (P < 0.05);there was no significant difference in depersonalization (DP) score between male and female (P > 0.05).The EE,DP and PAL scores of bank staff with post-graduate education were significantly lower than those with high school/secondary school and junior college/undergraduate (P < 0.05);the DP and PAL scores of bank staff with junior college/undergraduate were significantly lower than those with high school/secondary school(P < 0.05);there was no significant difference in EE score of bank staff between junior college/undergraduate and high school/secondary school(P > 0.05).The EE score of age > 50 years old bank staff was significantly lower than that of age < 30 years old,30-40 years old and 41-50 years old (P <0.05);there was no significant difference in EE score among age <30 years old,30-40 years old and 41-50 years old bank staff (P > 0.05).The DP score of 41-50 years old bank staff was significantly higher than that of age < 30 years old (P <0.05);there was no significant difference in DP score among age <30 years old,30-40 years old and 41-50 years old bank staff (P > 0.05).There was no significant difference in PAL score among all age groups (P > 0.05).The three dimensions of job burnout had significant negative correlation with self-efficacy and job satisfaction (P < 0.05).Conclusion Bank staff have a certain degree of job burnout.Age,sex,and education level maybe the influence factors of job burnout.Improvement of self-efficacy and job satisfaction may help to reduce the job burnout.
3.Three-dimensional finite element analysis of the zygapophyseal joints following artificial lumbar disc replacement
Hua WANG ; Daqi XU ; Jianzhong HU ; Kanghua LI ; Zhangyuan LIN ; Guanghua LEI
Chinese Journal of Tissue Engineering Research 2010;14(26):4915-4919
BACKGROUND: With deepening of spinal biomechanics, artificial lumbar disc replacement is considered to be the optimal choice for treating degenerative lumbar disease. However, studies concerning biomechanics of artificial lumbar disc are insufficient. OBJECTIVE: To establish the three-dimensional (3-D) finite element model of artificial lumbar disc replacement and to explore the effects of artificial lumbar disc replacement on zygapophyseal joints using biomechanical analysis. METHODS: Based on normal 3-D finite element model of lumbar motion segment, L4-5 intervertebral disc, superior and inferior endplates were removed, and then, the model of SB-Charite Ⅲ disc prosthesis was added, which remained annular fibrosus and ligaments at L4-5 intervertebral space. Thus, 3-D finite element model of L4-5 segments artificial lumbar disc replacement was constructed. Biomechanical analysis of this model was processed under axial load, forward flexion, lateral bending or posterior extension moments. The stress data were contrasted with the normal 3-D finite element model of artificial disc replacement. RESULTS AND CONCLUSION: After artificial lumbar disc replacement, the data of biomechanical analysis indicated: ①There was no significant differences between the zygapophyseal joint and normal segment of stress under axial load (P > 0.01).②Compared with normal segment, the stress of anterior, posterior of upper and lower vertebral body and bilateral zygapophyseal joint had no obviously difference under forward flexion and posterior extension moments (P > 0.01). ③The stress differences between the both sides of upper and lower vertebral body and bilateral zygapophyseal joint were not significant under lateral bending moment (P > 0.01). Artificial lumbar disc replacement can keep the stress of motion segment at normal level, which can meet the needs of spinal functional reestablishment.
4.Clinical value of combined detection of serological and biochemical test for Salmonellain
Xianmo WANG ; Zhangyuan YANG ; Liang MING ; Liangcai XIE ; Jinzhi LU ; Lin XIAO ; Yanlin LI
International Journal of Laboratory Medicine 2015;(11):1486-1487
Objective To explore the value of comprehensive biochemical and serological test in Salmonella clinical test .Methods A total of 95 cases of suspected salmonella infection with enteric fever were selected as subjects in this study from April 2013 to A‐pril 2014 ,and 48 cases randomly divided in research group ,47 cases in control group .Regular inspection was conducted in the con‐trol group ,comprehensive biochemical and serological test were conducted in the control group .Compared the results in the two groups .Results The salmonella detection rate in the research group was 93 .75% ,which was significant higher than 68 .09% in the control group (P< 0 .05) .Conclusion Combined detection of comprehensive biochemical and serology test could detect Salmonella effectively ,it is worthy of application and popularization in clinic .
5.Multiple of biochemical index test in the diagnosis of fatty liver
Xianmo WANG ; Zhangyuan YANG ; Liang MING ; Liangcai XIE ; Jinzhi LU ; Lin XIAO ; Yanlin LI
International Journal of Laboratory Medicine 2015;(12):1651-1652
Objective To explore a variety of levels of serum marker test applications in the diagnosis of fatty liver .Methods Data were randomly selected from April 2013 to April 2014 for treatment of patients with fatty liver hospital 45 cases ,set the study group ,choose the same period in healthy volunteers to undergo a medical examination in our hospital 45 cases ,it was set to control group ,two groups of subjects were taking a variety of levels of serum markers tested .Comparison and analysis of two groups of subjects to detect a variety of levels of serum markers and positive case detection rate .Results The study group subjects ALT , AST ,TG ,TC index the average level of detection was higher than the control group ,statistically significant differences (P<0 .01);study group subjects ALT ,AST ,TG ,TC index the positive rates were 77 .78% ,93 .33% ,55 .56% ,46 .67% more than 8 .89% in the control group ,4 .44% ,15 .56% ,11 .11% higher ,statistically significant differences (P<0 .05);United biochemical indicator de‐tection of biochemical indicators of detection rate of fatty liver was obviously higher than that of single detection rate ,the difference was statistically significant (P<0 .05) .Conclusion Multiple levels of serum markers of fatty liver diagnostic test in higher detec‐tion rate .
6.Transplantation of perforator flaps: Systematic review of 108 case series
Juyu TANG ; Kanghua LI ; Qiande LIAO ; Hongbo HE ; Zhangyuan LIN ; Jieyu LIANG ; Lin LUO ; Panfeng WU ; Dajiang SONG
Chinese Journal of Microsurgery 2010;33(3):186-189,后插1
Objective To explore the clinical outcome of perforator flaps for reconstruction of limb soft tissue defects. Methods In this case series, from 2007 July to 2009 May, 108 cases of perforator flap to reconstruct the defects of the extremities were performed, of these, 98 were free perforator flaps, 10 were pedicled flaps. The perforator flaps included deep inferior epigastric artery perforator flap, anterolateral thigh perforator flap, thoracodorsal artery perforator flap, lateral thigh perforator flap, posterior interosseous artery perforator flap, collateral radial artery perforator flap, medial sural artery perforator flap, posterior tibial artery perforator flap, deep circumflex iliac artery perforator flap and peroneal artery perforator flap. The maximum size of the perforator flap was 44 cmx 9 cm, the minimum size of the perforator flap was 4 em x 2 cm.The donor defect was closed directly. Results Venous congestion occurred in 5 flaps, in 1 case venous congestion was overcomed after released the dressing, 4 flaps requiring reexploration for venous insufficiency,2 had a successful outcome, the other 2 flaps failed . The other 103 flaps were successful. The wounds healed without any infection complications. The follow-up ranges from 6-24 months( 10 months on average). The flaps were of good appearance and not bulky; there were only linear scars on the donor sites, the cosmesis and function of the donor sites were satisfying. Conclusion The muscle, deep fascia and motor nerve are not contained in the flap, the advantages of this type of flap is reducing morbidity of the donor site and its reliable blood supply and suitable thickness for resurfacing, no secondary debuiking is necessary. The perforator flaps can be chosen as the first option to deal with superficial extremity wounds.
7.Treatment of Tile B pelvic fracture by external fixator combined with limited internal fixation.
Kanghua LI ; Yusheng LI ; Renjie LI ; Zhangyuan LIN ; Guanghua LEI ; Qiande LIAO
Journal of Central South University(Medical Sciences) 2010;35(6):630-633
OBJECTIVE:
To determine the effectiveness of external fixator combined with limited internal fixation for Tile B pelvic fractures.
METHODS:
Fourteen patients with Tile B pelvic fracture were treated by external fixator combined with limited internal fixation between September 2004 and June 2009.
RESULTS:
All the patients were followed for 6-49 (20.2 +/- 10.2) months. According to the Matta standard, the outcome of 9 patients was excellent, 4 patients were good, while the other one patient was fair.
CONCLUSION
External fixator combined with limited internal fixation is effective for Tile B pelvic fracture. It can not only reduce the anatomic position of the pelvis, but also strengthen the stability of the pelvis as a whole. This method is less invasive and traumatic, which promotes the recovery of patients.
Adult
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External Fixators
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Female
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Fracture Fixation
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methods
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Fracture Fixation, Internal
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methods
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Fractures, Bone
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surgery
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Humans
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Male
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Middle Aged
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Pelvic Bones
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injuries
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surgery
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Young Adult
8.Nerve decompression surgery for combined sacral plexus nerve injury through the lateral-rectus approach after sacral fracture fixation
Zilin LIANG ; Min ZENG ; Yong ZHU ; Ruibo ZHAO ; Haitao LONG ; Liang CHENG ; Zhangyuan LIN
Chinese Journal of Orthopaedic Trauma 2024;26(3):215-221
Objective:To investigate the efficacy and safety of nerve decompression surgery through the lateral-rectus approach for sacral plexus nerve injury after sacral fracture fixation.Methods:A retrospective study was conducted to analyze the 10 patients with combined sacral plexus nerve injury after sacral fracture fixation who had been admitted to Department of Orthopedics, Xiangya Hospital between May 2022 and May 2023. There were 2 males and 8 females with an age of 16.5 (15.0, 26.3) years. At the time of injury, the patients had been clearly diagnosed as sacral fracture combined with sacral plexus nerve injury. By the Denis classification of sacral fractures: 7 cases of type Ⅱ and 3 cases of type Ⅲ; sacral plexus nerve injury sites: 1 case of L 4, 8 cases of L 5, 7 cases of S 1, and 2 cases of S 2. All of them were treated with reduction and internal fixation via the posterior approach within 2 weeks after injury, but after surgery their manifestations of sacral plexus nerve injury still persisted which were confirmed by CT, magnetic resonance imaging and neuromuscular electromyography. Therefore, at (4.0±2.3) months after internal fixation, all patients were treated with nerve decompression surgery through the lateral-rectus approach. The operative time, intraoperative bleeding, length of hospitalization, Gibbons nerve damage score and neurological recovery at the last follow-up were recorded. Results:In the 10 patients, the operative time was (112.0±21.5) min, intraoperative bleeding (215.0±91.3) mL, and length of hospitalization 7.0 (6.0, 8.5) d. Intraoperatively, sacral plexus nerve compression was found in 9 cases (6 cases of nerve compression and pulling due to fracture displacement, 3 cases of nerve entrapment due to soft tissue scar adhesion), and 1 case of nerve root avulsion injury. No other intraoperative complications occurred. The 10 patients were followed up for (9.2±2.3) months after surgery. At the last follow-up, the Gibbons score for the 10 patients improved from preoperative 3.0 (3.0, 3.3) points to 1.0 (1.0, 2.0) point, and their British Medical Research Council (BMRC) nerve injury grading was improved from the preoperative grade 0.0 (0.0, 1.3) to grade 3.5 (2.8, 4.0) (1 case of M5, 4 cases of M4, 4 cases of M3, and 1 case of M2).Conclusion:The lateral-rectus approach is effective and safe for exploration and decompression of the sacral plexus nerve in patients combined with sacral plexus nerve injury despite sacral fracture fixation.
9.Effects of nerve block anesthesia versus general anesthesia on intertrochanteric fractures in the elderly
Shushan ZHAO ; Zhaohui LI ; Zhe RUAN ; Zhangyuan LIN ; Haitao LONG ; Ruibo ZHAO ; Zhengrong ZHU ; Bangbao LU ; Buhua SUN ; Liang CHENG ; Jianxi ZHU ; Zhaohui TANG ; Yong ZHU
Chinese Journal of Geriatrics 2018;37(12):1348-1351
Objective To retrospectively analyze the effects of nerve block anesthesia versus general anesthesia on intertrochanteric fracture in the elderly. Methods The 104 elderly inpatients undergoing closed reduction and intramedullary nailing for the treatment of femoral intertrochanteric fractures were recruited into this study at Department of Orthopedics ,Xiangya Hospital ,Central South University from January 2015 to June 2017.Medical records were collected and analyzed by SPSS 16.0 or GraphPad Prism 6.0 software. Results A total of 104 patients were divided into general anesthesia group(n= 48 )and nerve block anesthesia group (n= 56 ). There was no statistical difference in the demographic characteristics between the two groups. The changes in heart rate ,maximum changes of systolic/diastolic blood pressures ,and infusion volume during surgery were lower in the nerve block anesthesia group than in the general anesthesia group [(12.7 ± 7.3)vs. (18.1 ± 7.8)beats/min ,(22.5 ± 8.8/12.2 ± 7.5)mmHg vs. (34.3 ± 7.9/21.6 ± 6.6)mmHg ,(792.9 ± 387.0)ml vs. (1 083.0 ± 445.5)ml ,respectively ,t=3.64 ,7.14 ,6.73 ,5.16 ,all P<0.01]. There was no statistically significant difference between two groups in other perioperative data and the number of deaths at three months and one year after surgery. Conclusions As compared with the general anesthesia ,the nerve block anesthesia has less effects on the heart rate ,less maximum changes of systolic and diastolic blood pressures ,and less infusion volume during surgery ,and has no significant increase in postoperative mortality ,which is safe and worthy of further promotion.
10.The clinical efficacy of robot-assisted internal fixation with sacroiliac screws for posterior pelvic ring fractures: a meta-analysis
Zhi LIU ; Guoqing YIN ; Shushan ZHAO ; Ruibo ZHAO ; Haitao LONG ; Liang CHENG ; Bangbao LU ; Buhua SUN ; Ming ZENG ; Can CHEN ; Yong ZHU ; Zhangyuan LIN
Chinese Journal of Orthopaedics 2023;43(19):1324-1333
Objective:To compare the clinical efficacy of robot-assisted versus fluoroscopy-assisted sacroiliac screw internal fixation for posterior pelvic ring fractures.Methods:China National Knowledge Infrastructure (CNKI), Wanfang Data, Chinese Medical Journal Full-text Database, PubMed, Web of Science and ScienceDirect were searched for literature on robot-assisted versus fluoroscopy-assisted sacroiliac screw internal fixation for posterior pelvic ring fractures. The search time was from the establishment of each database to March 2023. Meta-analysis was performed on the included literature. The random-effects model was used when the heterogeneity between groups was large, and the fixed-effects model was used when the heterogeneity between groups was small.Results:A total of 15 studies were included in the meta-analysis, including 465 patients in the robot-assisted group and 396 patients in the fluoroscopy-assisted group. Meta-analysis showed that the number of fluoroscopies [ SMD=-3.12, 95% CI (-4.34, -1.89), P<0.001], the number of guide pin adjustments [ SMD=-3.75, 95% CI (-6.77, -0.72), P=0.015], intraoperative blood loss [ SMD=-0.83, 95% CI (-1.18, -0.49), P<0.001], and operative time [ SMD=-2.59, 95% CI (-4.11, -1.08), P<0.001] were smaller than those in the fluoroscopy-assisted group. The rate of excellent screw implantation [ OR=10.13, 95% CI (3.67,27.98), P<0.001] of the robot-assisted was larger than the fluoroscopy-assisted group. There was no significant difference in Majeed functional score [ SMD=0.28, 95% CI (-0.0003, 0.55), P=0.050] and fracture healing time [ SMD=-0.14, 95% CI (-0.46, 0.17), P=0.367] between the two groups. Conclusion:Robot-assisted percutaneous sacroiliac screw fixation for posterior pelvic ring fractures has the advantages of less fluoroscopy, less guide pin adjustment, less intraoperative blood loss, shorter operation time, and higher rate of excellent screw position. However, there is no difference in Majeed score and fracture healing time between robot-assisted percutaneous sacroiliac screw fixation and fluoroscopy-assisted percutaneous sacroiliac screw fixation.