1.Diagnosis of functional dyspepsia and an electrical bio-impedance technique
Zhangyong LI ; Na HU ; Chaoshi REN
International Journal of Biomedical Engineering 2009;32(2):125-127
Functional dyspepsia is a common disease in clinical service.Its etiology and pathogenesis are related to a variety of factors,and among them,gastric motility and gastrointestinal motility dysfunction are major causes.At present,diagnosis of functional dyspepsia depends maindy on the complaint of patients and no gastric motility detection method or means are effective enough to complete the diagnosis objectively.The electrical bioimpedance technique extracts information of gastric electrical activity and mechanical movement base on the recngnition of electricity-mechanism compound system and studies complicated procedure of gastric electrical activity,mechanical contraction and gastric peristalsis.The electrical bio-impedance technique has shown a promising clinical application and development prospects.
2.Factors affecting shoulder joint functions following artificial humeral head replacement: 22 cases analysis
Zhangyong TAN ; Shaocheng ZHANG ; Wankun HU ; Changsheng HUANG ; Hongwei ZHU
Chinese Journal of Tissue Engineering Research 2009;13(48):9550-9554
OBJECTIVE: To investigate the factors affecting shoulder joint functions following artificial humeral head replacement. METHODS: A total of 22 patients with complex fracture of proximal humerus, managed by humeral head replacement in Changhai Hospital of The Second Military Medical University from June 2006 to December 2008 were collected, including 12 males and 10 females, with average age of 67 years (52-86 years). During the procedure, soft tissue damage was minimized, the bone of the tuberosity was reserved as much as possible, appropriate matching size of humerus head prosthesis was selected, and early staging functional rehabilitation was performed. Neer's scoring system was used to evaluate the treatment results after replacement. RESULTS: The 22 patients were followed up for 10-30 months, mean 22.6 months. The shoulder joint functions of 14 cases were recovered more quickly through early post-operative staging rehabilitation, No shoulder joint unstable and stiff occurred. The shoulder joint functions of 8 cases were recovered slowly as they complained pain and did not perform early physical therapy after surgery, shoulder joint of 2 cases presented little unstable and 1 case presented stiff. Only 4 cases of all complained occasionally slight shoulder pain, but could continue daily work. The mean movement ranges of shoulder were as follow: mean flexion for 96°(80°-103°), mean extension for 38° (32°-45°), mean abduction for 86°(80°-110°), mean adduction for 31°(30°-35°), mean external rotation for 32°(30°-37°) and internal rotation for 42° (10°-75°). No vasculardamage, nerve damage, lessening prosthesis or prosthesis dislocation was found in all cases. Based on Neer's scoring system, 5 cases were rated as excellent, 11 as good and 4 as fair, with excellent rate of 82% and case satisfaction rate of 87%. CONCLUSION: In order to recover maximally the shoulder joint functions for post-artificial humeral head replacement, we must try our best to avoid soft tissue damage, reserve the bone of the tuberosity, select appropriate humerus head prosthesis, perform early post-operative staging rehabilitation, as well as maintain a normal retroversion of the prosthesis.
3.Expression of IL-18 in the peripheral blood mononuclear cells of chronic hepatitis B patients
Weiqun WEN ; Lian ZHANG ; Zhangyong HU ; Mingxia ZHANG ; Hong XIAO ; Yi QIAN
Immunological Journal 2001;(2):125-127
Objective To investigated the possible roles of IL-18 in HBV infection, and the expression of IL-18 in the peripheral blood mononuclear cells (PBMC) of chronic hepatitis B. Methods In 15 cases of asymptomatic carriers, 30 cases of active and remissive phases of chronic hepatitis and 10 healthy individuals (as normal controls), IL-18 expression in PBMC were quantitatively analyzed with flow cytometric immunological method. The PBMC were separated routinely and stimulated with LPS (SIGMA) and Monensin (SIGMA) for 6 hours. Then the cells were harvested and fixed by PBS/4% paraformaldehyde. The treated cells were stored in liquid nitrogen for detection later. After immunologic stain, the expression of IL-18 in PBMC were examined by flow cytometry. Results ① IL-18 was the lowest in asymptomatic carriers. It was fewer in remissive phase than in normal controls (P<0.01).There was no difference between active phase and normal controls(P=0.25).②Within the group of active phase, IL-18 was significantly different between each grade of inflammatory activity(P<0.01),and correlated with serum ALT positively(r=0.63,P<0.01). Conclusion IL-18 may relate to disease activity and the inflammation of liver.
4.Primitive experience of three dimensional multi-slice spiral CT angiography for the follow-up of intracranial aneurysm clipping
Yunjun YANG ; Weijian CHEN ; Qichuan ZHUGE ; Jingliang CHENG ; Zhangyong HU ; Enfu WU ; Meihao WANG ; Ming ZHONG ; Cuiping REN ; Yong ZHANG
Chinese Journal of Radiology 2008;42(1):43-46
Objective To evaluate multi-slice three-dimensional CT angiography (MS 3D-CTA) for the follow-up of intracranial aneurysm clipping.Methods MS 3D-CTA of 16 patients with intracranial aneurysm clipping were retrospectively analyzed.The patients were scanned on a 16-slice spiral CT(GE Lightspeed pro).Volume rendering(VR),thin maximum intensity projection(thin MIP) and multi-planar reconstruction (MPR) were employed in image postprocessing in all cases.Results There were 17 clips in the 16 patients with aneurysm clipping.Six clips were located at the posterior communicating artery,5 at the anterior communicating artery,4 at the middle cerebral artery,and the remaining 2 clips were located at the pericallosal artery in 1 patient.There were no abnormalities found in the aneurysm clipping region in 7 cases by MS 3D-CTA.There were residual aneurysm in 2 cases,parent artery stenosis in 4 cases,and artery spasm in 3 cases.There was no parent artery occlusion and clip displacement in all cases.VR showed excellent 3D spacial relations between the clip and parent artery in 12 cases,and showed good relations in 3 cases.The 1 case with 2 clips in the pericallosal artery showed heavy beam-hardening artifacts.The size and shape of aneurysm clips were clearly depicted by MPR and thin MIP,while 3D spacial relation of aneurysm clip and parent artery were poorly showed.Conclusion MS 3D-CTA is a safe and efficient method for the follow-up of intracranialaneurysm clipping.Combined VR with MPR or thin MIP can well reveal postoperative changes after aneurysm clipping.