1.The differential expression of apoptosis-associated genes in human gastric cancer MGC803 cells induced by diallyl trisulfide
Yali TAN ; Hao JIANG ; Wenxiang DAI ; Xiaoping WU ; Zhangwen TANG ; Qi SU
Chinese Pharmacological Bulletin 1986;0(06):-
Aim To investigate the differential expression of apoptosis-associated genes in human gastric cancer MGC803 cells induced by diallyl trisulfide(DATS).Methods Growth inhibition against MGC803 cells was assayed by MTT assay;The apoptosis induced by DATS was assessed by Flow cytometry and fluorescent microscope.The apoptosis-associated gene expression of MGC803 cell treated with DATS was determided by Human Apoptosis Gene Array.Apaf-1 and SODD genes were confirmed by RT-PCR.Results DATS had significant growth inhibitory activity against MGC803 cells,inhibition ratio increased from 11% to 78% at 4,8,12,16 and 24 mg?L-1 for 72 h(P
2. A study of an independent dose verification software for brachytherapy
Xianliang WANG ; Pei WANG ; Churong LI ; Jie LI ; Shengwei KANG ; Min LIU ; Ting TANG ; Zhangwen WU ; Qing HOU
Chinese Journal of Radiation Oncology 2020;29(2):131-135
Objective:
To report an implementation method and results of an independent brachytherapy dose verification software (DVS).
Methods:
The DVS was developed based on Visual C+ + and the modular structure design was adopted. The DICOM RT files exported from the treatment planning system (TPS) were automatically loaded into the DVS. The TG-43 formalism was employed for dose calculation. Six cervical cancer patients who underwent brachytherapy were retrospectively selected to test the DVS. Different applicators were utilized for each patient. Dosimetric parameters and