Factors which influence the extraction of Chinese materia Medica were comprehensively studied,by ex-tracting each single herb component in the compounded preparation Sinitang as the sample,and determiningthe extraction rate as well as the content of main active principle in each extract as the evaluation criteria. Thegeneral ru1e for the extraction of single herb material was then investigated. The results indicated that it isbetter to desigm the experiment in accordance with it's characteristic object with selection of proper evalua-tion criteria to obtain an optimum process for the extraction of Chinese traditional drugs.

A simple,reliable RPHPLC method on ODS column with UV detector for deter-mination of the anticoagulant rodenticide coumatetralyl in animal tissue was developed.1,1′-Bi-(2-Naphthol)was used as an internal standard to check the process ofexperiments.The mean recoveries from the spiked rabbit liver were around 90% atthe levels of 0.4-16mg/kg.The coeffecint of variation of 5 determination was 3.2%.The results showed that this method has a satisfactory reproducibility.The methodis practical for examining poisons in poisoning cases.