Objective To discuss the treatment of cervical cancer in different stages.Methods The treat- ment of 42 cases of cervical cancer in this hospital from January 2000 to December 2005 was analysed,and clinical treatment modalities were analysed too.Results(1)A total of 6 cases of uterine carcinoma in situ received hysterec- tomy plus bilateral salpingo-oophorectomy.(2)A total of 26 cases was inⅠb-Ⅱa stage,of which 15 cases with cer- vical cancer were treated with a simple radical hysterectomy;6 cases of cervical cancer were radiotherapied after radi- cal hysterectomy;7 cases of cervical cancer received radical hysterectomy plus radiotherapy.(3)A total of 10ⅡbⅣstage eases selected radiotherapy and chemotherapy.Conclusion Different treatment should be applied in differ- ent stages of cervical cancer,and the choice for treatment is important for patients' quality of life after treatment. Comprehensive treatment can improve the survival of patients with cervical carcinoma.

Objective To propose a new classification scheme of otitis media (OM). Methods By reviewing current internat ional classification systems of OM, we analyzed their disadvantages and the prog ress made in histopathologic studies of OM, then worked out a new classification scheme to apply it to clinic. Results In current internati onal classification systems of OM, those apparent clinical signs are regarded as main standards of classification. Their main disadvantage is that these signs c annot very well indicate the condition of pathologic and functional changes of i mportant hearing structure areas. We proposed a “Three-stage Scheme” of OM cl assification and applied in 1 160 cases of OM. The accuracy rate of diagnosis w as 82.4% in 348 cases of early-stage OM, 98.4% in 696 cases of chronic OM, and 95.2% in 116 cases of OM sequela. Conclusion The “Three-s tage Scheme” system is scientific, simple and practical. Its accuracy rate of d iagnosis is very high. It plays a guiding role in diagnosis and treatment of OM.

Objective To compare therapeutic effect of single hemoperfusion and hemoperfusion combined with continuous veno-venous hemofiltration ( sequential continuous blood purification) on patients with severe acute organophosphate poisoning combined with myocardial injury.Methods A total of 80 patients with severe acute organophosphate poisoning combined with myocardial injury admitted to EICU of Beijing Chaoyang Hospital from Jan.2004 to Dec.2013 were respectively analyzed and divided into two groups: hemoperfusion group (patients collected from Jan.2004 to Dec.2008, n=41) and sequential continuous blood purification (patients collected from Jan.2009 to Dec.2013, n =39).The average cholinesterase recovery time, the average consciousness recovery time, the average doses of atropine, the average hospital time, the change of cardiac troponin I levels on days 1, 2, 3, 5 and 7 after admission, and the change of left ventricular ejection fraction within 24 h after admission and after 24 h following blood purification treatment were compared between the two groups.Results Patients in the sequential continuous blood purification group had less average cholinesterase recovery time, average consciousness recovery time, average doses of atropine and average hospital time compared with patients in the hemoperfusion group [ ( 87.6 ±8.8 ) h vs.( 113.8 ±13.3 ) h;(57.3 ±11.7) h vs.(100.5 ±10.8) h;(284.5 ±61.4) mg vs.(476.6 ±93.1) mg and (10.2 ±2.3) vs. (14.6 ±3.9) , all P<0.01].The levels of cardiac troponin I on days 2, 3, 5 and 7, and ejection fraction of left ventricule after 24 h following blood purification treatment in the sequential continuous blood purification group were significantly decreased compared with patients in the hemoperfusion group ( all P <0.05 ) . Conclusion Therapeutic effect of sequential continuous blood purification on patients with severe acute organophosphate poisoning combined with myocardial injury is superior to single hemoperfusion.It suggests that sequential continuous blood purification could be used as a preferred choice in treatment of patients with severe acute organophosphate poisoning combined with myocardial injury.

Objective To investigate and analyze the relative factors in elderly men with type 2 diabetes mellitus(T2DM)complicated with osteoporosis(OP),thus to provide guidance for prevention of OP complicated with T2DM in elderly men.Methods Dual X -ray absorptiometry determination of bone mineral density (BMD)of 67 cases of elderly men with diabetes,men were divided into OP group (n =32),NOP group (n =35).Then,we compared differences in body mass index(BMI),diabetes duration,fasting plasma glucose (FPG),glycosylated hemo-globin(HbA1c),patients'age,fasting insulin(FINS),insulin sensitivity index(ISI),quantitative of urinary albumin (ALb),quantitative of urinary protein in 24 hours and alkaliphosphatase level(ALP),low density lipoprotein choles-terin(LDL -C),triglyceride(TG),and made correlation analysis.Results Compared with those in NOP group,pa-tients in OP group had older age,longer disease course,smaller baric index,lower BMD,higher ALP,lower FINS,low-er ISI,higher HbA1c,higher quantitative of urinary protein in 24 hours and urinary albumin,higher LDL -C,which were significantly different (P <0.05);BMD of elderly men with T2DM was negatively correlated to patients'age, disease course,HbA1c,quantitative of urinary protein in 24 hours,ALb,ALP and LDL -C,but positively correlated to BMI,FINS and ISI.Conclusion Many factors,such as elderly,low body weight,long duration of the disease,high level of blood sugar,insulin dysfunction,low insulin sensitivity,high level of blood suger,insulin dysfunction,low insulin sensitivity,high serum alkalinephosphatase,high LDL -C and diabetic nephropathy,contribute to osteoporosis in elderly men with T2DM.

Selective COX-2 inhibitors can promote the apoptosis of tumor cells and block the growth of new blood vessels through the inhibition of ring oxidase,vascular endothelial growth factor,microvessel and so on. Research shows that COX-2 is overexpressed in vascular and endothelial cells of lung cancer,select COX-2 inhibitors to adjuvant chemotherapy,not only can directly inhibit the tumor proliferation,but also can reduce the adverse reaction of chemotherapy drugs,and enhance the curative effect. To investigate the effects of selec-tive COX-2 inhibitors and cisplatin in lung cancer angiogenesis and its mechanism,will be a hope for the clini-cal treatment of tumor.

COX-2 is the inducible form of cyclooxygenase,which is overexpressed in non-small cell lung cancer,especially in the adenocarcinoma,and is involved in the production of lung cancer drug resistance, reducing the sensitivities of tumor cells to chemotherapy drugs. COX-2 inhibitors have the effects of antitumor and prevention of tumor formation. Therefore,in order to reverse the drug resistance of tumor cells,improve the sur-vival rate and the prognosis of patients with tumor,the application of COX-2 inhibitors as adjuvant chemotherapy and combined with chemotherapy drugs has become a new direction in the treatment of lung cancer.

This paper introduced the importance of the air medicine system,and features and advantages of its development in the USA,Switzerland and Germany,and China's status quo.In view of the slow development of air medicine,imbalanced development and different operation models of air medicine systems in localities,and different models of emergency medicine services in the country,the paper proposed to build a model of government guidance and business operation as support for air medicine against emergency events,providing air ambulance service; to build an air medicine system featuring both public welfare and business operation,reasonable layout,timely response,and efficient operation,which will enhance the overall capacity of air medicine.

It is the trend to integrate the curriculum contents and strengthen the ability training in reform of edu-cation model at present .After the abilities to develop and maintain medical informatics-related information sys-tems, to process medical information and to provide medical information service were analyzed, certain suggestions were put forward for the practical teaching reform of medical informatics according to the requirements of ability training and the characteristics of subject knowledge structure .

Objective To analyse the CT imaging characteristics of solitary pulmonary tuberculous cavity in order to improve its diagnosis level.Methods 29 cases of pulmonary tuberculous cavities comfirmed by pathology or operation.All the patients were underwent examination of contrast-enhanced CT.Results 29 cases were all solitary pulmonary cavities,93%(27/29) were located at the superior lobe of lung.The average diameter was 23.5 mm.73% of the cavities were round or similar round.The majority of the cavities (82%,24/29) were less or no lobulated;76%(22/29) were thick cavities and 51%(15/29) were less smooth both in and outside the cavities.The cavities were less enhancement.All cases along with satellite nodules.Conclusion The pulmonary tuberculous cavities are majority thick cavities.The important points for tuberculous cavities to diffierent from lung cancer and other disease cavities are:are there any satellite nodules along with the cavites,lobulated or not,the growth of CT enhancement of cavitied before and after enhancement.

Objective:To study influence of type 2 diabetes mellitus (T2DM) on ambulatory blood pressure (ABP) levels and blood pressure variability (BPV) in aged patients with essential hypertension (EH) .Methods:A total of 80 aged EH +T2DM patients treated in our hospital from Jun 2014 to Jan 2016 were selected as observation group ,another 80 aged pure EH patients were selected as EH control group .The 24hABP indexes and BPV indexes were compared between two groups . Results:Compared with EH control group , there were significant rise in 24h mean systolic blood pressure [24hSBP , (126.47 ± 9.64) mmHg vs .(134.98 ± 10.63) mmHg] ,nighttime mean SBP [nSBP ,(125.73 ± 10.19) mmHg vs .(133.74 ± 11.29) mmHg] ,daytime mean SBP [dSBP ,(128.29 ± 10.97) mmHg vs .(136.42 ± 12.18) mmHg] ,daytime mean pulse pressure [dPP ,(59.46 ± 10.79) mmHg vs .(65.38 ± 11.69) mmHg] ,nPP [ (58.00 ± 10.11) mmHg vs .(67.14 ± 9.93) mmHg] and 24hPP [ (59.27 ± 10.16) mmHg vs .(64.76 ± 11.62) mmHg] , P<0.01 all;and significant rise in 24hSBP standard deviation [24hSBPSD ,(12.63 ± 2.87) mmHg vs .(18.41 ± 3.09) mmHg] and nSBPSD [ (10.14 ± 3.53) mmHg vs .(14.89 ± 3.54) mmHg] in observation group , P<0.01 both .Conclusion:Diabetes mellitus elevates daytime and nighttime SBP ,increases BPV and risk of cardiovascular diseases in aged EH patients .