Objective To summarize the clinical experience of living relative donor kidney transplantation.Methods A retrospective analysis on 19 cases of living relative donor kidney transplantation from February 2002 to May 2006 was carried out.Results No blood transfusion was needed and no serious postoperative complications occurred in donors.The 19 donors were discharged from hospital at 7～10 days postoperatively.Follow-up examinations for 1～51 months(mean,28 months)in the 19 donors revealed normal liver and renal functions.Among the 19 recipients,follow-up examinations for 1～51 months(mean,28 months)showed that the renal functions recovered in 3～5 postoperative days in 16 recipients and within 3 weeks after transplantation in 3.Acute rejection occurred in 2 recipients postoperatively,and was reversed by steroid pulse therapy in 1 recipient and by ALG treatment for 10 days in 1 recipient,in whom the hormone pulse therapy was invalid.The hormone treatment was needed for only 3 weeks in a renal transplantation between monozygotic twins,without using other immunosuppressors,and no acute rejection occurred.Two patients with an uneventful recovery developed an acute rejection because of voluntary decrement and even stopping of immunosuppressor after 6 months,and then was treated with hormone pulse treatment until a reversion.The 1-year survival rate for patient/kidney was 100%.Conclusions Living relative donor renal transplantation is safe and feasible,offering a high survival rate for patient/kidney.

OBJECTIVETo compare the lingual region upper airway CT scan results of OSAS patients and normal adults to explore if there are upper airway stricture in OSAS patients and the reason of stricture.

METHODS59 patients with OSAS and 57 normal adults were included in the study. CT evaluated the lingual region upper airway with the use of a Philips Tomoscan AV Expander E1 spiral scanner. The shapes of lingual region upper airway were observed. The area and the dimensions of lingual region was studied, and the thickness of retropharyngeal and lateral pharyngeal tissue were evaluated too. The another focus area was tongue, and the evaluated data included the tongue width, genioglossus width, hyogolssus width, tongue length and tongue area.

RESULTSThe data comparative results of OSAS and normal groups were as follows: the right to left diameter and area of OSAS patients' lingual region upper airways were less than those of normal adults, the thickness of lateral pharyngeal, tongue width, genioglossus width, hyogolssus width and tongue area were more than those of normal adults. And there were not obviously difference between OSAS patients and normal adults in tongue length, anterior-to-posterior dimension and thickness of retropharyngeal wall tissue of upper airway.

CONCLUSIONSThe study suggests that there are obviously difference between the patients with OSAS and normal adult in lingual upper airway CT scan measure. And the anatomic stricture of lingual upper airway is one of the etiology of OSAS. The main reasons of stricture are increasing of thickness of lateral pharyngeal, tongue width, genioglossus width, hyogolssus width and tongue area.

Adult ; Female ; Humans ; Male ; Middle Aged ; Pharynx ; diagnostic imaging ; Sleep Apnea, Obstructive ; diagnostic imaging ; Tomography, X-Ray Computed ; methods ; Tongue ; diagnostic imaging