OBJECTIVE:To investigate the current abroad market state of the cephalosporin and its trend of develop?ment.METHODS:The cephalosporin abroad was analyzed in aspects of general sales situation,products structure,research and development,and the manufacture situation.RESULTS&CONCLUSION:The sales volume of the cephalosporin abroad has been decreasing annually,its predominance position over the other antibiotics has been losing.The future development&re?search trend of antibiotics is broad-spectrum,high-effective slow-released oral preparations.

Objective To explore the effect of different temperature of the forced- air warming system on the prevention of hypothermia during laparotomy of infants. Methods A total of 60 infants undergoing laparotomy under general anesthesia were recruited and divided into three groups by random digits table method with 20 cases each according to admitting time; when used the force- air warming system intraoperatively, the three groups were respectively setting on 45℃(automatic adjustment for 43 ℃ after 45 minutes), 43 ℃ and 38 ℃.The core temperature were respectively recorded before anesthesia and 15, 30, 45, 60 minutes after anesthesia (every 30 minutes after 1 hour).The hypothermia incidence and anesthesia recovery conditions were recorded simultaneously. Results There was no significant difference on the core temperature among three groups before anesthesia (P > 0.05). 30 minutes after the anesthetic, the core temperature of 45 ℃ group was (36.31±0.20) ℃,43 ℃ group was (36.32±0.24) ℃ and 38 ℃ group was (36.08±0.21) ℃.The differences among three groups was statistically significant (F=8.12, P < 0.01), but there was no significant difference between 45 ℃ group and 43 ℃ group (P > 0.05). 60 minutes after the anesthetic, the core temperature of 45 ℃ group was (36.39±0.26) ℃,43 ℃ group was (36.19±0.22) ℃ and 38 ℃ group was (35.92±0.15) ℃. The differences among three groups was statistically significant(F=25.19, P<0.01).The hypothermia incidence of 45℃group, 43℃ group,38℃ group was 10.0%(2/20), 25.0%(5/20), 50.0%(10/20)respectively and the differences among three groups was statistically significant( χ2=8.04, P<0.05). The time to complete consciousness of 45 ℃ group was (15.40±5.09) minutes,43 ℃ group was (19.80±4.10) minutes and 38 ℃ group was (22.00±4.36) minutes. The differences among three groups was statistically significant (F=10.96, P<0.01). The time to tracheal extubation of 45 ℃ group was (18.10±5.97) minutes, 43 ℃ group was (21.85±4.02) minutes and 38 ℃ group was (24.90±5.54) minutes.The differences among three groups was statistically significant (F=9.83, P<0.01). Conclusions The forced-air warming system can increase the infants′peripheral tissue heat content and reduce the heat losing.So that it will help decrease the intraoperative hypothermia incidence and shorten the anesthesia recovery period.Meanwhile the higher temperature of the forced-air warming system is setted ,the better effect it is.

Objective To investigate the clinical efficacy of biological dressing A covering bandage of Ⅲ° burn wounds given comprehensive treatment including dermabrasion.Methods For patients of non Ⅲ° ° burn wounds (deep Ⅱ ° and partial superficial Ⅲ ° wounds),28 cases in the treatment group,were given improved dermabrasion with tangential excision plus thin layer of skin graft from the body,the wounds were covered with biological dressing A bandage.21 patients in the control group were treated by traditional tangential excision,escharectomy and self-skin grafting.The clinical treatment effect was observed and compared between the two groups.Results The wounds were healed 2 ～ 3 weeks after surgery in treatment group,the cure rate of burns in patients with a total area of 40％ ～ 50％ TBSA was 99％,and after treatment the scar formation significantly reduced,self-donated skin significantly reduced,the hospital stay and postoperative recovery time of the patients were significantly shorter,patients were easier to accept.In the control group,the operation time was longer,the blood loss was more,the wounds had more scar healing wounds.The wound healing time of the treatment group was (14.8 ± 1.8) d,which was significantly shorter than (19.4 ± 3.0) d of the control group (P ＜ 0.05).Conclusion The improved grinding A scab plus biological dressings covering bandage has the advantages of simple operation,light damage,less complications,need less skin,to maximize retention of healthy tissue,wound healing speed up,healing scar lessened.

Objective:To investigate the training status of robotic-assisted surgery nurses in hospitals with robotic-assisted surgery system in China, and to provide reference for the training and management of robotic-assisted surgery nurses.Methods:From August to December in 2021, hospitals with robotic-assisted surgery system in China were surveyed by a self-designed questionnaire distributed online.Results:The participants in the survey of 111 hospitals in 30 provinces, cities, autonomous regions and municipalities directly under the central government, nurses cooperated with robotic-assisted surgery exist the phenomenon of their own training was up to 96.40% (107/111) of hospital, 47.75% (53/111) of the hospital said the current training content also need to add other aspects of the course. Training duration of theoretical courses was 0-13 (2.86 ± 3.03) periods arranged by hospitals, and the training duration of practical courses was 1-60 (8.38 ± 9.91) d. 35.14% (39/111) of hospitals set up regular assessment after training, and the assessment cycle of them was 1-12 (4.08 ± 3.31) months. Many hospitals put forward suggestions on strengthening English training and attaching importance to team cooperation and so on.Conclusions:In our country, Robotic-assisted surgery nurses′ training has turned to that training themselves in operating rooms, the training time, form, content and other aspects have no uniform standard, strict admittance, standardization of specialist training , these are questions need to solve.

Objective:To evaluate the effects of the defect situational objective structured clinical examination (OSCE) in the training of specialized nurses in the operating room, and provide a new idea for the training of specialized nurses in the operating room.Methods:A quasi experimental study was used in this study. A total of 78 nurses who participated in the training of the operating room specialized nurses in Henan Province in 2022 and 2023 which were organized by the First Affiliated Hospital of Zhengzhou University were selected by cluster sampling method. The nurses who participated in the training in 2022 and 2023 were assigned to the control group (38 participants) and the experimental group (40 participants), respectively. Nurses in the experimental group received defect situational OSCE, while nurses in the control group received conventional teaching. After the training, the effect of the two teaching methods was evaluated by skill operation assessment results and Clinical Thinking Ability Assessment Scale.Results:There were 4 males and 34 females in the control group, aged (30.03 ± 4.33) years old, and 3 males and 37 females in the experimental group, aged (29.93 ± 3.95) years old. The scores of the verification and handover of surgical patients, surgical position placement and the occupational exposure protection were (91.80 ± 2.95), (90.38 ± 3.66), (91.10 ± 3.26) points in the experimental group and were (89.08 ± 3.21), (87.84 ± 3.49), (88.39 ± 4.21) points in the control group, the differences between the two groups were statistically significant ( t = 3.91, 3.13, 3.18, all P<0.05). The total score of clinical thinking ability in the experimental group was (80.66 ± 1.85) points, which was higher than (77.77 ± 1.62) points in the control group, the difference between the two groups was statistically significant ( t = 7.31, P<0.05). The evaluation of the teaching effect in the experimental group was better, and the satisfaction rate was 92.5%(37/40)-100.0%(40/40). Conclusions:The application of defect situational OSCE teaching method in the training of operating room nurses could better improve the operational ability and help to improve the clinical thinking ability of nurses. The training effect is superior to the conventional teaching method, and it is worthy of clinical application.

Objective? To explore the effects of health failure mode and effect analysis(HFMEA) in the safety management of intraoperative radiotherapy(IORT). Methods? The HFMEA group was set up to analyze the potential risks of breast cancer patients undergoing intraoperative radiotherapy from January 2014 to April 2018. The group listed the failed modes that need to be improved, identified the invalid steps that need intervention, determined the causes of the failure and calculated the risk priority number (RPN), created the safety management plans and put them into action. Finally, the outcomes were observed and analyzed. Results? After the improvement of the HFMEA, the patients' healing rate of stage-Ⅰ incision increased from 85.42% to 98.18% with statistical significance (χ2=4.184,P＜0.05). The patients' satisfaction degree scored (98.21±3.98)from the patients and (99.02±5.89)from the surgeons, both higher than those before improvement with statistical significance (t=5.24, 3.07;P＜0.05). After the improvement, the absorbed and scattered dose of the affected and contralateral skin of thyroid gland, and the absorbed and scattered dose of the affected and contralateral skin of lens were lower than those before improvement. Conclusions? Through prospectively controlling non-standard operation behaviors and optimizing the process, the application of HFMEA in the intraoperative irradiation after conservative surgery for breast cancer can ensure patients' safety and improve the quality of surgeries.

Objective:To formulate a safety check plan for intraoperative magnetic resonance imaging (IMRI) , and provide a reference for the management of the combined MRI operation room.Methods:Totally 207 intracranial mass lesion surgeries performed in the combined MRI operation room of the First Affiliated Hospital of Zhengzhou University in 2019 were selected. Based on the visual management theory, the "point-to-point" fixed homing method and the "four-party" safety checklist for IMRI were designed to adjust the surgical process. After optimization, the surgeons, anesthesiologists, itinerant nurses and magnetic resonance physicians who participated in the scan safety check were interviewed to evaluate the effect of process improvement. The interview data were collected and analyzed using Colaizzi's phenomenological seven-step analysis method.Results:The interviews with surgeons, anesthesiologists, itinerant nurses and magnetic resonance physicians could boil down to two themes: fixed-point placement of items could ensure the safety of IMRI; "four-party" safety check could ensure patients' safety.Conclusions:The optimized surgical process in the combined IMRI operation room and the scanning safety check plan can ensure the safe homing of non-compatible items, improve the efficiency of scanning safety check, and enhance the safety of IMRI.

Objective:To explore the effects of defect situation simulation method based on peer aid in teaching for undergraduate operating room nursing students.Methods:Totally 80 undergraduate nursing students admitted in 2016 who had their internship in the Operating Room at the First Affiliated Hospital of Zhengzhou University from September to December 2019 were selected by convenient sampling and randomly divided into the experimental group and the control group, with 40 cases in each group. Nursing students in the control group received traditional operating room nursing operation training, while nursing students in the experimental group were taught with the defect situational simulation method based on peer aid. The nursing skills assessment performance was compared between the two groups, and the teaching methods of the two groups of nursing students were investigated with an evaluation questionnaire.Results:The operating room nursing skills assessment performance of the experimental group was (92.88±4.29) , while that of the control group was (89.83±5.01) , the difference was statistically significant ( t=-2.925, P < 0.01) ; the score of nursing effects in the experimental group was 42.00 (40.00, 44.00) , whereas that of the control group was 39.00 (38.00, 40.00) , and the difference was statistically significant ( Z=-4.67, P<0.01) . Conclusions:The defect situation simulation method based on peer aid can better improve the operating room nursing skills of nursing students, help cultivate their teamwork awareness and problem-solving skills, promote the transformation of teaching concepts, and improve the quality of nursing teaching in the operating room.

Objective:To understand the real feelings and needs of postgraduate nursing students during standardized training, and provide a reference for managers to formulate more complete standardized training programs in the future.Methods:Using the phenomenological research method, totally 12 postgraduate nursing students of the First Affiliated Hospital of Zhengzhou University who had completed the two-year standardized training were selected by purposive sampling and received semi-structured interviews from August to October 2018, and the Colaizzi 7-step method was used to organize and analyze the data.Results:A total of 5 themes were extracted, namely, increased self-efficacy and improved core competence, negative psychological experience, demand for policy guarantees for scientific research, demand for personalized training programs and high-standard teaching staff, and demand for the promotion system and salary.Conclusions:The recognition of various aspects is dominant in postgraduate nursing students, but they have also many negative emotions and unmet needs. Managers should pay attention to their feelings and needs, and properly formulate suitable training programs, thereby giving full play to the advantages of standardized training.

Objective:To explore the current status of clinical nurses' perception of authentic leadership, scientific research ability, and self-transcendence, and analyze the path relationship among them.Methods:This study was a cross-sectional study. In June 2020, convenience sampling was used to select clinical nurses from two Class Ⅲ Grade A hospitals in Zhengzhou as the research object. The survey was conducted using the General Information Questionnaire, Authentic Leadership Questionnaire (ALQ) , Nursing Research Capacity Self-evaluation Questionnaire, and Self-Transcendence Scale (STS) . This study collected 913 questionnaires, of which 897 were valid questionnaires, with a valid rate of 98.25%.Results:Among 897 clinical nurses, the ALQ total score, Nursing Research Capacity Self-evaluation Questionnaire total score and the STS total score were (58.72±6.72) , (47.42±18.23) and (37.94±7.86) respectively. The structural equation model showed that with self-transcendence as an intermediary, the indirect effect of authentic leadership on scientific research ability was 0.15.Conclusions:Self-transcendence plays a mediating role between nurses' perception of authentic leadership and scientific research ability. Nursing managers should take effective measures to cultivate authentic leadership behaviors, promote the improvement of nurses' self-transcendence level, and thereby enhance nurses' scientific research capabilities.