5.Treatment of oral mucosal diseases: Part I. Diagnosis and treatment of oral leukoplakia, erythroplakia and melanoplakia.
Chinese Journal of Stomatology 2006;41(8):502-505
Erythroplasia
;
diagnosis
;
epidemiology
;
therapy
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Humans
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Leukoplakia, Oral
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diagnosis
;
epidemiology
;
therapy
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Mouth Mucosa
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pathology
9.Inhibitory Effect of Chinese Herbal Compound Dongju on Tongue Carcinogenesis in Rats
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(10):-
Objective To examine the inhibitory effect of Chinese herbal Compound Dongju on 4-nitroquinoline 1-oxide(4NQO)-induced tongue carcinogenesis in rats. Methods A total of 85 Wistar rats were divided into four groups: model group(n=35),administration group(n=35),normal control group(n=5) and herb control group(n=10).4NQO dissolved in drinking water was administered orally to induce tongue carcinogenesis in rats.The herb compound was injected into the stomach of the rats during oral carcinogenesis.Rats were sacrificed at 9,13,20,24 and 32 weeks from the beginning of the experiment.The tongues of the rats were dissected for gross and histological assessment,and SP immunohistochemical method was also employed to detect the expression of cyclin D1 in the specimens. Results Compared with the model group,the incidence of dysplasia and the positive rate of cyclin D1 were suppressed by Compound Dongju(P
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