1.Survey and Analysis of the Factors Affecting Civil Will Towards donating Cadaver in Guangzhou
Junhua ZHOU ; Mingyue LI ; Huiyu LI ; Jinxin PAN ; Zehuai LIN
Chinese Medical Ethics 1995;0(03):-
Objective: To get the information about the civil will of donating cadaver in Guangzhou. Method: Make stochastic visit to dwellers in Guangzhou.Result: Traditional concept,legal system and lack of the knowledge of donating cadaver affect the civil will most. Conclusion: More effects are needed to update the social viewpoints and strengthen the legal system.
2.Applying the CDISC Therapeutic Area Standards to Improve the Efficiency of Clinical Trials of Traditional Chinese Medicine for the Treatment of Chronic Obstructive Pulmonary Disease:An Initiative
Wenhan ZHAO ; Meiling XUAN ; Geng LI ; Lei WU ; Zehuai WEN ; Lin LIN
Traditional Chinese Drug Research & Clinical Pharmacology 2024;35(8):1255-1263
In order to better promote the standardization of clinical research data,the Clinical Data Interchange Standards Consortium(CDISC)has established a series of clinical research data standards,and issued the Therapeutic Area(TA)standard for chronic obstructive pulmonary disease(COPD)in January 2016.This treatment domain standard is used to identify common data standards for clinical research protocols for COPD,to support the integration of clinical trial data from different sources and at different times,thus to promote the secondary analysis of cohort data.This article introduces the structure and content of the standard user guide for the treatment of COPD,in order to help researchers better understand and use the standard in the field of COPD treatment in research design.It is proposed to apply the standard in the field of treatment to standardize the design of clinical trials of traditional Chinese medicine for COPD,so as to promote the integration of research data and improve the efficiency of clinical trials.
3.Exploration on the Development of Evidence-based Grading System for Chinese Medicine Interventional Clinical Evidence
Shaonan LIU ; Xinfeng GUO ; Darong WU ; Anthony Lin ZHANG ; Charlie Changli XUE ; Zehuai WEN
Journal of Traditional Chinese Medicine 2023;64(18):1885-1889
The grading of evidence is an important factor in clinical decision-making. The current evidence grading system based on western medicine is limited in the clinical practice of traditional Chinese medicine (TCM), therefore we propose the solutions to the development of grading system for TCM interventional evidence, following the international evidence grading standards, taking into considerations of the unique characteristics of TCM practice, based on the Grades of recommendation, assessment, development and evaluation (GARDE) evaluation system, and integrating with grading system regarding TCM classical literature and empirical evidence from modern famous doctors. The evidence from classical literature is suggested to be evaluated from three aspects including source of ancient medical records, comprehensive of treatment details, and the inheritance. The qualification of famous doctors, content integrity, and inheritance of experiences will be used to evaluate the evidence from famous doctors' experience. The multi-sourced evidence such as TCM classical literature, experience of modern famous doctors, and modern researches is mainly integrated in a qualitative way, and the overall level of evidence of TCM interventions will be graded consistently with the GRADE system based on modern research. The evidence from classical literature and modern famous doctors' experience will be assessed and considered as supplementary evidence, which will make the evaluation of clinical evidence more objectively and comprehensively, thereby guiding clinical practice further.