1.Depression among chronic pain patients at Hospital Tengku Ampuan Rahimah, Klang
Hon Fei Seed ; Hazli Zakaria ; Muralitharan Perumal ; Azlin Baharudin
The Medical Journal of Malaysia 2015;70(5):303-306
Introduction: Despite the high prevalence rates of
depression amongst chronic pain patients reported globally,
the condition is often under-recognised and under-treated.
Depression frequently complicates the effective
management of pain and is associated with poor quality of
life. This study aimed to explore the incidence of depression
and its’ associated factors in a sample of chronic pain
patients in Malaysia.
Materials and methods: This descriptive cross-sectional
study was conducted amongst clinically diagnosed chronic
pain patients from the pain management clinic of Hospital
Tengku Ampuan Rahimah over a period of seven months.
Socio-demographics and clinical data were obtained from
patients’ interview and medical records. The validated
Depression Anxiety Stress Scale-21 (DASS-21) was used for
screening and Mini International Neuropsychiatric Interview
(MINI) was used to establish the depression diagnoses
among the patients. Numeric pain intensity scale was used
to assess the severity of pain.
Results: Eighty-three patients with a mean age of 50.4±12.50
years participated in this study. The majority of the patients
were females (56.6%), married (85.5%) and being employed
(49.4%). The percentage of depression was 37.4%.
Depression was significantly associated with severity of
pain (p<0.001) and the duration of pain (p <0.05).
Conclusion: Almost one third of chronic pain patients in this
study have depression. Depression was significantly
associated with the severity and duration of pain.
Depression should be regularly screened among patient
with chronic pain.
Depression
;
Pain Management
2.Brain Atrophy And Psychosis In An Untreated Attention Deficit Hyperactivity Disorder (Adhd) With Ecstasy Abuse
Mohamad Ayob Ismail ; Hazli Zakaria ; Hajar Mohd Salleh Sahimi ; Khairi Che Mat, ; Hatta Sidi
ASEAN Journal of Psychiatry 2018;19(1):13-
Objective: Long-term use of ecstasy is known to be a risk factor for structural brain damage and psychosis. Most patients suffering from ADHD in childhood will not develop psychosis during adulthood but the risk is increased when there is concomitant significant drug use. However, it is difficult to distinguish between substance-induced psychoses with schizophrenic psychosis. Method: We report a case of a patient with history of ADHD who was untreated, who later developed psychotic symptoms soon after initiation of ecstasy uses. The symptoms persisted despite in a ‘drug-free period’ and intensified while on the ecstasy. Results: Present case helps to understand common neurobiological mechanism behind psychosis and brain atrophy, and risk factors such as ADHD and ecstasy abuse. Conclusion: More research in this area is vital for management and further understanding on the importance of treating ADHD earlier and to be more vigilant in establishing the history of substance use.
3.Objective structured clinical examination (OSCE) in psychiatry new curriculum undergraduate posting and its standard setting procedure: An experience in Universiti Kebangsaan Malaysia (UKM)
Wan Salwina Wan Ismail ; Ruzanna ZamZam ; Nik Ruzyanei Nik Jaafar ; Marhani Midin ; Azlin Baharudin ; Hazli Zakaria ; Hatta Sidi
ASEAN Journal of Psychiatry 2010;11(1):118-127
Objective: This study aims to report on the process of standard settings (SS) and to compare the passing rates between the norm-reference and SS methods, for OSCE in psychiatry undergraduate examination at UKM for 2009/2010 session. Methods: In the SS method, examiners were asked to imagine the performance of a minimally competent student and gave marks using a standardized check-list. The marks in particular outliers were discussed. After the first round, the examiners went through the same process again, to rate the minimally competent students independently. The median of the marks was taken as the passing mark for the particular question. The passing rate using the passing mark of 50% in the norm-reference method was compared to the passing rate from the passing mark obtained from the settings method. Results: For question 1, the passing rate with the norm-reference method (i.e. passing mark of 50%) was 93% (106/114) and that by the SS method was 72.8% (83/114). For question 2, the pass rate with the norm-reference method was 92% (105/114) and that by the SS method was 67.5% (77/114). Conclusion: The passing rates between the two methods showed significant differences. Although OSCE is an improvement to the undergraduate psychiatry examination in Universiti Kebangsaan Malaysia, there were few limitations and challenges that need to be tackled for further improvement.
4.Factors influencing inpatient duration among insanity acquittees in a malaysian mental institution
Chan Lai Fong ; Phang Cheng Kar ; Loo Tsui Huei ; Ong Lieh Yan ; Tuti Iryani Mohd Daud ; Hazli Zakaria ; Suarn Singh ; Rabaiah Mohd Salleh
ASEAN Journal of Psychiatry 2010;11(1):23-35
Objective: According to Malaysian law, defendants found not guilty by reason of insanity may be admitted to a psychiatric hospital and discharge is subject to the state ruler’s assent. The objective of this study is to examine the clinical, socio-demographic and forensic factors that influence inpatient duration of insanity acquittees in a Malaysian mental institution. Methods:
This is a cross-sectional study of one hundred and twelve insanity acquittee inpatients in Hospital Bahagia Ulu Kinta from January 2007 to February
2007. Patients with a clinical diagnosis of schizophrenia, major depressive disorder and bipolar disorder were assessed using the Positive and Negative Syndrome Scale (PANSS), Hamilton Depression Rating Scale (HAMD) and Young Mania Rating Scale (YMRS) respectively. Other relevant socio-demographic, clinical and forensic factors were also assessed. Results: The inpatient duration varied widely from three months to forty-seven years with a median of seven years. Seventy five percent of patients were in remission. According to the multiple linear regression model, the strongest predictor of a longer duration of hospital stay for insanity acquittees was older age (p<0.001) followed by murder as the index offence (p=0.005). Good family support predicted a shorter inpatient duration. This model explains 56% of
the variance in the inpatient duration. Conclusion: Social factors such as family support may be increasingly important in determining the discharge process of insanity acquittees besides clinical rehabilitation. Issues such as stigma of violent forensic patients and the role of community forensic rehabilitation services need to be further explored.
5.Impulse control behaviours in a Malaysian Parkinson’s disease population
Shahrul Azmin ; Eng Liang Tan ; Nik Jaafar Nik Ruzyanei ; Zakaria Hazli ; Azmawati Mohammed Nawi ; Zhe Kang Law ; Remli Rabani ; Wan Yahya Nafisah ; Ramesh Sahathevan ; Hui Jan Tan ; Nur Fadhlina M. Pakarul Razy ; Nor Azian Abdul Murad ; King-Hwa Ling ; Mohamed Ibrahim
Neurology Asia 2016;21(2):137-143
Background: Impulse control behaviours are repetitive and excessive activities that may be subsyndromal
and not fulfil the criteria for impulse control disorder. These activities have potential to
negatively impact on the daily lives of sufferers. We conducted a study to investigate the prevalence
of impulse control behaviours and its associated features in Parkinson’s disease in our population.
Methods: We conducted a prospective cross-sectional study on consecutive patients attending neurology
clinic. Inclusion criteria include idiopathic Parkinson’s disease patients with Hoehn & Yahr stage I-IV.
Eighty patients were enrolled and screened for impulse control behaviours using the Questionnaire
for Impulsive-Compulsive Disorder for Parkinson’s disease (QUIP). Results: Prevalence of impulse
control behaviours among our cohort was 11.3%; the features significantly associated with it were
higher level of education (p=0.02), advanced stage of disease (p=0.03) and higher levodopa dosage
(p= 0.01). The commonest impulse control behaviour in our cohort was compulsive medication use
(7.5%), followed by hobbyism (6.3%), hypersexuality (5%), compulsive buying (3.75%), punding
(2.5%), walkabout (2.5%), compulsive eating (1.25%) and pathological gambling (1.3%).
Conclusions: There is an association between impulse control behaviour and higher levodopa dosage
in a study on patients with Parkinson’s disease in Malaysia. We also found a low prevalence of
pathological gambling as compared to studies performed in the West.
Disruptive, Impulse Control, and Conduct Disorders
;
Parkinson Disease