OBJECTIVE:To research the correlation between per capita disposable income,investment of pharmaceutical advertisement,people’s healthy level,pharmaceutical price and the demand of drugs in China METHODS:Based on the economical theory,the methods of the econometrics and the Eviews were adopted to establish the model of demand function RESULTS & CONCLUSION:Under the background of the non-full competition,the improvement of people’s living conditions can lead to the demand of drugs The changes of drug price have little influence on the demand of drugs

The coronary collateral circulation is an alternative source of blood supply to the myocardium jeopardized by failure of the original vessel to provide adequate flow. Angiogenesis growth factors induce angiogenesis to promote collateral circulation, been demonstrated in a number of different animal test and phase Ⅰ clinical experience to induce collateralization in the ischemic area and improve cardiac function. Although there are several unsolved questions, the pharmacologic use of angiogenesis growth factors will represent a viable therapeutic alternative for the patients with ischemic heart disease.

By generalizing the integrity crisis of college students,the article analyzes the causes of this phenomenon,and proposes a series of measures aiming at strengthening integrity education,establishing the favorable environment,completing the mechanism of rewards and punishments and building the credit system,in the hope of securing the deepening and full completion of good-faith education at college,both ideologically and systematically.

Aged ; Calcinosis ; complications ; Heart Aneurysm ; complications ; Heart Ventricles ; Humans ; Male ; Thrombosis ; complications

Acupressure ; Acupuncture Points ; Child ; Child, Preschool ; Enuresis ; physiopathology ; therapy ; Female ; Humans ; Male ; Treatment Outcome ; Urination

Objective To study on the correlation of hepatic fibrosis with angiotensin Ⅱ (Ang Ⅱ ) in the hepatitis B patients . Methods The electrochemical luminescence and the rate method were adopted to detect hyaluronidase (HA) and Ang Ⅱ levels in 92 cases of acute hepatitis B (acute group) ,108 cases of chronic hepatitis B(chronic group) and 50 healthy people(control group) , and the detected results were performed the correlation analysis .Results Compared with the acute group and the control group ,the HA and Ang Ⅱ levels in the chronic group were increased significantly (P<0 .05) .The HA and Ang Ⅱ levels had statistical differ-ence between the acute group and the control group (P<0 .05) .Further analysis showed that there was a positive correlation be-tween HA and Ang Ⅱ levels(r=0 .629 ,P<0 .05) .Conclusion There the HA level is closely related with the Ang Ⅱ level ,and both of them participate in the process of liver fibrosis ,their levels have the guiding significance in evaluation of severity of liver fi-brosis in the patients with hepatitis B .

Fetuin A is a kind of glycoprotein that is synthesized and secreted by the liver.It is a natural inhibitor of insulin receptor tyrosine kinase,which is involved in the formation of insulin resistance.It is closely related to the nonalcoholic fatty liver disease.This paper reviews the related research on effect of fetuin A in the occurrence and development of non-alcoholic fatty liver disease.

Objective To study the mechanism of haze formation after photorefractive keratectomy (PRK). Methods 27 adult New Zealand white rabbits were employed in this study.24 of them received PRK in the right eye and laser in situ keratomileusis (LASIK) in the left eye at the same time and under the same condition for -10\^00D ablation at once,24hour,1 week,2 week,1month,3 month,6 month and 12 month after surgery,the corneas were examined periodically by slip\|lamp microscopy for haze formation,and the both eyes of 3 rabbits were enucleated,the corneas were studies with light microscopy;transmission electron microscopy;immunohistochemical evaluation for extracellular matrix,including collagen type Ⅰ,type Ⅲ,type Ⅵ,cellular fibronection,tenascin and laminin;RT\|PCR detection for mRAN of collagen type Ⅰ. Results The incidence of haze was 100% after PRK.No haze formation after LASIK.Haze was located at the anterior stroma immediately adjacent to the ablated areas.The change of structure and composition which correlated with haze formation was due to a combination of the following factors:the basement membrane of corneal epithelium was discontinuous;A new layer of subepithelium tissue was synthesized;fibroblast was increased in number and activated;the collagen fibrils were disorganized.The diameter of fibrils and the space between the fibrils were irregular in the anterior stroma;The newly synthesized extracellular matrix inculding collagen type Ⅰ,type Ⅲ,type Ⅵ,cellular fibronection,tenascin and laminin were deposited in the anterior corneal stroma.Conclusion\ The formation and disappearing of haze was the result of interreaction between fibroblast and extracellular matrix.The destruction of basement membrane of corneal epithelium and Bowmen's member after PRK is initializing factor during haze formation.\;[

Objective To investigate the relationship between auxotypes,antibiotic resistance and plasmid of Neisseria gonorrhoeae. Methods 83 isolates of Neisseria gonorrhoeae from Chongqing during the period from January 1994 to November 1995 were examined.Results Eight auxotypes were detected in 83 strains. The prevalent auxotypes were proline requiring strains (51.8%) and nonrequiring (18.1%). The agar dilution method was performed to detect the susceptibility of 83 isolates to pencillin,tetracycline and spectinomycin, the results indicated that 15.6% of strains was penicillin resistant,70% was tetracycline resistant, 1.2% was spectinomycin resistant. Plasmid profile of 44 isolates,which was tested by rapid alkaline extraction method, showed that 70% of the strains carried 24.5 Md conjugative plasmid, 80% carried 2.6Md cryptic plasmid, 66% carried both 24.5Md and 2.6Md plasmids, and no plasmid was found in 16% of the strains. In Pro - strains both penicillin resistant strains and 24.5Md plasmid carrying strains were more common than other auxotypes (P

Asymptomatic bacteriuria is common in diabetic patients. This article reviews several aspects of asymptomatic bacteriuria in diabetes mellitus, including prevalence, mechanisms, coexisting risk factors, bacteriology, treatment and prognosis.