2.The prevention and treatment of chronic diseases: an important heavy task with an uneasy long haul
Chinese Journal of Endocrinology and Metabolism 2015;31(10):837-838
The prevalence of obesity,type 2 diabetes,and other chronic non-communicable diseases is increasing rapidly world-wide.Most recent epidemiological data showed that China is now in an era of obesity,and under a huge burden of the complications related with obesity,diabetes,as well as cerebral-and cardiovascular disorders.Strenuous efforts,comprehensive strategies,effective measures,and practical solutions must all be taken to combat against these chronic diseases.
3.Question on Baihu Jia Renshen decoction syndrome in Shanghan Lun
International Journal of Traditional Chinese Medicine 2010;32(1):29-31
According to the texts of Baihu Jia Renshen Decoction in the books of Maijing,Qianjin Yaofang,Qianjin Yifang,Taiping Shenghui Fang,Hxin Fang,and Jingui Yuhan Jing,the author drew the following conclusions:Baihu Jia Renshen Decoction in the present Shanghan Lun was very likely the written error Of Baihu Decoction,which was more close to the original meaning of Zhang Zhong-jing.From the period of Sui and Tang Dynasty,doctors had gotten new experiences in their practices.They added Ginsen into Baihu Decoction and named the new decoction"BaihU Jia Renshen Decoction",which was still in use today.Although there was not intrinsically difierence between Baihu Decoction and Baihu Jia Renshen Decoction,while the saying of"adding Renshen or not,should be decided by patient's Yuanqi"by doctor Shu Chi-yuan in Qing Dynasty had a significant impact.The erroneous views by some recent scholars can't be complied with,who advocated that the four main symptoms of Baihu Decoction syndrome should belong to syndrome of Baihu Jia Renshen Decoction according to the original texts in Shanghan Lun.
4.Periosteal kneading plus resistance exercise for obstructive sleep apnea syndrome
Chinese Journal of Physical Medicine and Rehabilitation 2012;(11):829-833
Objective To observe the effect and mechanism of periosteal pressure kneading plus resistance exercise in improving obstructive sleep apnea/hypopnea syndrome (OSAHS).Methods Thirty-two patients with moderate OSAHS were divided randomly into a kneading plus resistance training group and a conventional drug group,each group with 16 patients.The training group was given periosteal pressure kneading plus resistance exercise while the drug group received only conventional oral treatment with drugs.Before and after treatment,polysomnography (PSG),Thera-Band elastic bands and a PWS angle measuring instrument were used to observe PSG parameters around the neck plus the muscle strength and cervical activity of both groups.Results In the training group the following components of the PSG index had improved significantly compared with before treatment:respiratory events (AHI),sleep structure (SS),awakening number (AN),non-rapid eye movement (NREM),rapid eye movement (REM),mean oxyhemoglobin saturation (MSaO2) events,lowest oxyhemoglobin saturation (LSaO2),and the index of oxyhemoglobin saturation decrease (ODI).In the drug group only the LSaO2 and ODI had improved significantly compared with before treatment.In terms of the PSG parameters,the training group demonstrated significantly greater improvement than the drug group.After treatment,the training group's average residence time in neck load pulling was extended significantly while that of the drug group showed no significant change.The difference between the groups was statistically significant.After the treatment the training group's average activity of the cervical spine was also significantly increased,and again the drug group showed no significant improvement.Conclusion Skeletal lesions in peripheral airways may be an important factor in the formation of OSAHS.Periosteum kneading with resistance exercise has an obvious curative effect on OSAHS.
5.Digitalized revolution on medical thermostat water bath cauldron
Chinese Medical Equipment Journal 2003;0(10):-
Medical thermostat water bath cauldron is widely used in clinic,but its temperature control is not accurate.This paper presents a digitalized revolution on medical thermostat water bath cauldron.
6.Pathogenic Bacteria Distribution and Drug Resistance of Hospital Infection in Pediatrics Unit
Chinese Journal of Nosocomiology 2005;0(11):-
OBJECTIVE To investigate the major pathogenic bacteria and drug resistance of hospital infection in pediatrics unit,and to provide laboratory evidence for clinical diagnosis and treatment.METHODS Pathogenic bacteria were isolated from patients who suffered from hospital infection in pediatrics unit from 2004 to 2006.the method was taken to carry out the sensitive test and bacteria identification by VITEK32,Streptococcus pneumoniae,Moraxella catarrhalis and Haemophylus influenzae were assayed with French Bio-Merieux API System ATB STREP5 and ATB HAEMO,respectively.RESULTS Totally isolated strains were 489.Of them,108 strains of coagulase negative Staphylococcus(CONS),being 22.1%.58 strains were S.haemolyticus.The isolated rate of CONS was 53.7%.The drug test for meticillin-resistant coagulase negative Staphylococcus(MRCNS) showed multiple drug-resistance.The detection rate of the ESBLs from the Escherichia coli and the Klebsiella pneumoniae was 18.9% and 12.5%,respectively.CONCLUSIONS MRCNS are the major pathogens in pediatrics unit.The detectable rate of MRCNS is high.Glycopeptide antibiotics are the first-choice drugs for MRCNS infection.
7.Laparoscopic Biliary Reoperation
Chinese Journal of Minimally Invasive Surgery 2001;0(01):-
Objective To evaluate the feasibility and clinical efficacy of laparoscopic biliary reoperation. Methods From May 2000 to May 2007, 105 patients received laparoscopic biliary reoperation, including choledocholithotomy and T-tube drainage in 96 cases, Roux-en-Y anastomosis of the gallstone/hepatic-duct in 5, and liver resection in 4. Results The operations were completed in all the 105 patients without severe complications. The operation time was 60-185 min [mean, (125.3?23.2) min]. Intraoperative blood loss was 15-310 ml [mean, (21.1?8.6) ml]. The patients stayed at hospital for 5-9 days after the operation. The 5 patients, who underwent Roux-en-Y anastomosis of the gallstone/hepatic-duct, were followed up for 6 to 65 months [mean, (13.2?8.6)months]. Partial liver resection was performed in 2 cases (resection of the left hepatic lobe in 2, and the right lobe in 2); they were followed up for 8-25 months [mean, (10.2?3.6)months]. In the 96 patients, who received laparoscopic choledocholithotomy and T-tube drainage, the follow-up were lasted for 3-72 months [mean, (13.2?9.6)months]. None of the patients who were followed up had recurrence of gallbladder stone. Conclusions Laparoscopic biliary reoperation is feasible and safe with minimal trauma to patients.
8.Effect of atorvastain on plasma levels of nitric oxide and alpha-granule membrane protein in patients with acute cerebral infarction
Chinese Journal of Primary Medicine and Pharmacy 2006;0(07):-
Objective To investigate the effect of atorvastain on plasma levels of nitric oxide(NO) and alpha-granule membrance protein-140(GMP-140) in patients with acute cerebral infarction.Methods 94 cases with acute cerebral infarction were randomly divided into the atorvastain group(48 cases) and the control group(46 cases).Plasma NO and GMP-140 were determined by the method of nitrate reductase and enzyme-linked immunosorbent assay in atorvastain group and control group at moment of hospitalization and after four weeks.Results Plasma NO and GMP-140 of atorvastain group after treatment were statistically lower than that of controls(P0.05).Conclusion Atorvastain can reduce plasma levels of NO and GMP-140 in patients with acute cerebral infarction.It can ameliorate brain injury after ischemia and has protective effect on the ischemia cerebral tissue.
9.Effects of celecoxib on the expression of PGE2 and VEGF A549 cell lines
Chinese Journal of Practical Internal Medicine 2001;0(04):-
Objective To investigate the effect of the selective cyclooxygenase-2 inhibitor celecoxib on the expression of PGE2 and VEGF induced by IL-1? in A549 cell lines.Methods A549 cells were incubated with IL-1? in the presence or absence of celecoxib.After indicated incubation time,cells were harvested to detect VEGFmRNA by reverse transcription-polymerase chain rection(RT-PCR),the medium was collected to determine the concentration of PGE2 and VEGF by enzyme-linked immunosorbent assay(ELISA).Results After Celecoxib intervention,the formation of PGE2 and VEGF expression decreased more than control group(IL-1? induced),the difference being significance(P
10.Distribution of bacteria and drug-resistance to antibiotics in patients with lower respiratory tract infections diseases in RICU
Chinese Journal of Practical Internal Medicine 2003;0(01):-
Objective To investigate the distribution,the drug-sensitivity tests and drug-resistance of bacteria in patients with lower respiratory tract infections diseases in respiratory intensive care units(RICU).Methods Retrospective study of the clinical data,the distribution and the drug-sensitivity of bacteria of 178 cases with mechanical ventilation in RICU.The drug-sensitivity were examined by Kribry-Bauer(KB)paper method and minimal-inhibitory-concentration(MIC)by agar double dilute method.Results A total of 326 strains bacteria were obtained in 178 patients.Among 326 strains G-bacteria were the most common kinds of bacteria(78.2%);main kinds of the G-bacteria were pseudomonas areuginosa(30.4%)and baumanii(23.0%);fungus was the second commonest kind of bacteria(16.6%).Most of the G+ bacteria were staphycoccus aureus.In 107 cases more than two kinds of bacteria were obtained.The drug sensitivity test in vitro showed that these strains were multiresistant to commonly used antibiotics,and drugs whose sensitive rate was over 70% included meropenem,impienem,cefoperazone/sulbactam,amikacin and piperacillin/tazabactam,the sensibility of vancomycin to G+ bacteria being 100%.Conclusion Pseudomonas areuginosa,baumanii and fungus are the main pathogens of the patients in RICU;meropenem,impienem,cefoperazone/sulbactam,amikacin and vancomycin are effctive antibiotics for treating lower respiratory tract infection in RICU.There is mixed infection by various bacteria,and some strains are multiresistant.We should monitor drug-sensitivity to bacteria dynamic and use antibiotics reasonably.