1.Summary of the best evidence for nutrition management of sarcopenia in maintenance hemodialysis patients
Luchen CHEN ; Huajuan SHEN ; Yongze DONG ; Meiling ZHOU ; Xiujun XU ; Yan JIANG ; Mengjiao ZHAO ; Shiyan YAO ; Guannan MA ; Haixin SONG
Chinese Journal of Modern Nursing 2025;31(34):4665-4674
Objective:To summarize the best evidence for nutrition management of sarcopenia in patients undergoing maintenance hemodialysis (MHD), to guide the development of nutrition management programs.Methods:Using the 6S evidence model, literature on nutrition management of sarcopenia in MHD patients was electronically retrieved from databases and websites including UpToDate, Guidelines International Network, Joanna Briggs Institute Evidence-Based Health Care Center Database, European Society for Clinical Nutrition and Metabolism, UK Kidney Association, PubMed, Web of Science, China Biology Medicine disc, China National Knowledge Infrastructure, and Wanfang Data. The search period was from database establishment to July 30, 2024. After screening and quality assessment of the literature, evidence was extracted and summarized.Results:A total of 19 articles were included, comprising one clinical decision, six guidelines, five systematic reviews, five expert consensus, and two randomized controlled trials. Twenty-six pieces of evidence were summarized from six aspects of nutrition team establishment and counseling, nutritional screening and assessment, nutritional support, nutrient intake, nutritional monitoring, and health education.Conclusions:The evidence summary on nutrition management of sarcopenia in MHD patients provides a basis for implementing nutritional interventions. Evidence transformation and application should be conducted in accordance with patient preferences and the actual clinical context.
2.Analysis of the Fulfillment Index for Malignant Neoplastic Deaths among Urban Residents in 2020
Liye ZHOU ; Sijing CHEN ; Mengjiao SUN
Chinese Journal of Health Statistics 2025;42(2):171-174
Objective Analyzing the impact of malignant tumors on the life expectancy of urban residents of different ages and genders.Methods Applying the Fulfillment Index proposed by Prithwis Das Gupta,analyze the 2020 national urban resident mortalitysurveillance data by age and gender using Excel software.Results In 2020,the lifeexpectancy at birth for the urban population was 81.21 years(78.80 years for males and 83.80 years for females).The loss of life expectancy due to malignant tumors was 2.90 years(3.33 years for males and 2.32 years for females).The majority of deaths from malignant tumors were concentrated in the 40~60 age group,and the impact on potential life expectancy increased with age.The 60- age group experienced the highest loss of potential life expectancy due to malignant tumors.There were differences in the Fulfillment Index between males and females.The highest Fulfillment Index for males was in the 60- age group(40.68),while for females,it was in the 40- age group(47.85).In age groups below 60,the Fulfillment Index for females was consistently higher than that for males,indicating a trend of malignant tumors occurring at a younger age in females.Conclusion The loss of life expectancy due to malignant tumors varies across different age groups and genders,highlighting the need for different prevention and treatment priorities.Health authorities should guide and enhance public awareness of malignant tumor prevention to help extend life expectancy.
3.Influencing factors for sarcopenia among elderly male patients with type 2 diabetes mellitus
LI Meilin ; ZHOU Mengjiao ; WU Jiayun ; YU Zhe ; KONG Liping
Journal of Preventive Medicine 2025;37(6):588-592
Objective:
To explore the influencing factors for sarcopenia among elderly male patients with type 2 diabetes (T2DM), so as to provide the basis for the early prevention and treatment of sarcopenia.
Methods:
Male T2DM patients aged 60 and above admitted to Hangzhou First People's Hospital from January to December 2024 were selected as the study subjects. Demographic data, T2DM complications, and blood biochemical parameters were collected. Physical activity levels were assessed using the Chinese version of the International Physical Activity Questionnaire. The diagnosis of sarcopenia was made according to the diagnostic procedures and criteria established by the Asian Working Group for Sarcopenia in 2019. Factors affecting sarcopenia among elderly male patients with T2DM were analyzed using multivariable logistic regression model.
Results:
A total of 455 elderly male patients with T2DM were surveyed, with a mean age of (71.80±9.55) years. The predominant physical activity level was moderate with 226 cases accounting for 49.67%. The disease course of T2DM was mainly from 10-<20 years, with 229 cases accounting for 50.33%. There were 140 cases of T2DM complications, accounting for 30.77%. A total of 138 cases of sarcopenia were detected, with a prevalence of 30.33%. Multivariable logistic regression analysis showed that age (OR=1.077, 95%CI: 1.003~1.156), body mass index (<18.5kg/m2, OR=11.056, 95%CI: 3.343~36.547; 18.5~<25.0 kg/m2, OR=2.633, 95%CI: 1.420~4.881), physical activity level (low, OR=2.469, 95%CI: 1.421~4.292), chronic obstructive pulmonary disease (yes, OR=1.871, 95%CI: 1.091~3.206), T2DM complications (yes, OR=3.015, 95%CI: 1.516~6.001), glycated hemoglobin (≥7%, OR=2.822, 95%CI: 1.423~5.590) and albumin (OR=0.810, 95%CI: 0.662~0.991) were factors affecting sarcopenia among elderly male patients with T2DM (P<0.05).
Conclusion
Advanced age, body mass index <25.0 kg/m2, low physical activity level, chronic obstructive pulmonary disease, T2DM complications, high glycated hemoglobin and low albumin are associated with a higher risk of sarcopenia in elderly male patients with T2DM.
4.Summary of the best evidence for nutrition management of sarcopenia in maintenance hemodialysis patients
Luchen CHEN ; Huajuan SHEN ; Yongze DONG ; Meiling ZHOU ; Xiujun XU ; Yan JIANG ; Mengjiao ZHAO ; Shiyan YAO ; Guannan MA ; Haixin SONG
Chinese Journal of Modern Nursing 2025;31(34):4665-4674
Objective:To summarize the best evidence for nutrition management of sarcopenia in patients undergoing maintenance hemodialysis (MHD), to guide the development of nutrition management programs.Methods:Using the 6S evidence model, literature on nutrition management of sarcopenia in MHD patients was electronically retrieved from databases and websites including UpToDate, Guidelines International Network, Joanna Briggs Institute Evidence-Based Health Care Center Database, European Society for Clinical Nutrition and Metabolism, UK Kidney Association, PubMed, Web of Science, China Biology Medicine disc, China National Knowledge Infrastructure, and Wanfang Data. The search period was from database establishment to July 30, 2024. After screening and quality assessment of the literature, evidence was extracted and summarized.Results:A total of 19 articles were included, comprising one clinical decision, six guidelines, five systematic reviews, five expert consensus, and two randomized controlled trials. Twenty-six pieces of evidence were summarized from six aspects of nutrition team establishment and counseling, nutritional screening and assessment, nutritional support, nutrient intake, nutritional monitoring, and health education.Conclusions:The evidence summary on nutrition management of sarcopenia in MHD patients provides a basis for implementing nutritional interventions. Evidence transformation and application should be conducted in accordance with patient preferences and the actual clinical context.
5.Analysis of the Fulfillment Index for Malignant Neoplastic Deaths among Urban Residents in 2020
Liye ZHOU ; Sijing CHEN ; Mengjiao SUN
Chinese Journal of Health Statistics 2025;42(2):171-174
Objective Analyzing the impact of malignant tumors on the life expectancy of urban residents of different ages and genders.Methods Applying the Fulfillment Index proposed by Prithwis Das Gupta,analyze the 2020 national urban resident mortalitysurveillance data by age and gender using Excel software.Results In 2020,the lifeexpectancy at birth for the urban population was 81.21 years(78.80 years for males and 83.80 years for females).The loss of life expectancy due to malignant tumors was 2.90 years(3.33 years for males and 2.32 years for females).The majority of deaths from malignant tumors were concentrated in the 40~60 age group,and the impact on potential life expectancy increased with age.The 60- age group experienced the highest loss of potential life expectancy due to malignant tumors.There were differences in the Fulfillment Index between males and females.The highest Fulfillment Index for males was in the 60- age group(40.68),while for females,it was in the 40- age group(47.85).In age groups below 60,the Fulfillment Index for females was consistently higher than that for males,indicating a trend of malignant tumors occurring at a younger age in females.Conclusion The loss of life expectancy due to malignant tumors varies across different age groups and genders,highlighting the need for different prevention and treatment priorities.Health authorities should guide and enhance public awareness of malignant tumor prevention to help extend life expectancy.
6.A real-world study on the features of postpartum hepatitis flares in pregnant women with chronic HBV infection
Zhan ZENG ; Mingfang ZHOU ; Yanjie LIN ; Xiaoyue BI ; Liu YANG ; Wen DENG ; Tingting JIANG ; Leiping HU ; Mengjiao XU ; Lu ZHANG ; Wei YI ; Minghui LI
Chinese Journal of Hepatology 2024;32(2):113-118
Objective:To analyze the clinical features of postpartum hepatitis flares in pregnant women with hepatitis B virus (HBV) infection.Methods:A retrospective study was conducted. Patients who met the enrollment criteria were included. Liver function and HBV virology tests were collected from pregnant women with chronic HBV infection at delivery, 6, 24, 36, and 48 weeks after delivery through the hospital information and test system. Additionally, antiviral therapy types and drug withdrawal times were collected. Statistical analysis was performed on all the resulting data.Results:A total of 533 pregnant women who met the inclusion criteria were included, with all patients aged (29.5±3.7) years old. A total of 408 cases received antiviral drugs during pregnancy to interrupt mother-to-child transmission. There was no significant difference in the levels of alanine aminotransferase (ALT, z ?=?-1.981, P ?=?0.048), aspartate aminotransferase (AST, z ?=?-3.956, P ?0.001), HBV load ( z ?=?-15.292, P ?0.001), and HBeAg ( z ?=?-4.77, P ?0.001) at delivery in patients who received medication and those who did not. All patients ALT, AST, total bilirubin, direct bilirubin, and albumin showed an upward trend within six weeks after delivery. A total of 231 cases developed hepatitis within 48 weeks after delivery. Among them, 173 cases first showed ALT abnormalities within six weeks postpartum. Conclusion:Hepatitis flare incidence peaked six weeks after delivery or six weeks after drug withdrawal in pregnant women with chronic HBV infection.
7.Cone-beam computed tomography study of root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology in high-angle Class Ⅱ open bite patients
Qingyuan REN ; Lina BAO ; Mengjiao ZHOU ; Chunlan WU
Journal of Prevention and Treatment for Stomatological Diseases 2024;(3):196-201
Objective This study aimed to explore the root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology in patients with high-angle skeletal Class Ⅱ open bite,aiming to provide a refer-ence for clinical treatment.Methods This study was reviewed and approved by the Ethics Committee,and informed consent was obtained from the patients.CBCT images of eighty-one untreated patients(40 anterior open bite patients and 41 normal overbite patients)with high-angle skeletal Class Ⅱ malocclusion were selected before treatment.Dolphin software was used to study the root length of maxillary and mandibular anterior teeth and central incisor crown-root mor-phology,and the differences between the two groups were analyzed.Results There was no statistical significance in the root length of maxillary lateral incisor and canine between the open bite group and the normal overbite group,signifi-cant differences were found in the root length of maxillary central incisor(11.12±1.37)mm、mandibular central inci-sor(10.15±1.09)mm,mandibular lateral incisor(11.27±1.15)mm and mandibular canine(12.81±1.48)mm be-tween the open bite group and the normal overbite group(P<0.05).On the other hand,the two groups were significant-ly different in crown-root morphology of the maxillary central incisor(1.10°±3.62° vs.4.53°±2.30°,P<0.01)but not in the mandibular central incisor.Conclusion The root length of the maxillary central incisor,mandibular central inci-sor,mandibular lateral incisor,mandibular canine in high-angle Class Ⅱ open bite patients is shorter than that in high-angle Class Ⅱ normal overbite patients,and the long axis of the crown of the maxillary central incisor in high-angle Class Ⅱ open bite patients obviously deviates toward the labial side relative to the long axis of the root.The crown-root angle is smaller,which is beneficial to torque control or adduction movement of the anterior teeth in high-angle Class Ⅱopen bite patients.
8.Cone-beam computed tomography study of root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology in high-angle Class Ⅱ open bite patients
Qingyuan REN ; Lina BAO ; Mengjiao ZHOU ; Chunlan WU
Journal of Prevention and Treatment for Stomatological Diseases 2024;(3):196-201
Objective This study aimed to explore the root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology in patients with high-angle skeletal Class Ⅱ open bite,aiming to provide a refer-ence for clinical treatment.Methods This study was reviewed and approved by the Ethics Committee,and informed consent was obtained from the patients.CBCT images of eighty-one untreated patients(40 anterior open bite patients and 41 normal overbite patients)with high-angle skeletal Class Ⅱ malocclusion were selected before treatment.Dolphin software was used to study the root length of maxillary and mandibular anterior teeth and central incisor crown-root mor-phology,and the differences between the two groups were analyzed.Results There was no statistical significance in the root length of maxillary lateral incisor and canine between the open bite group and the normal overbite group,signifi-cant differences were found in the root length of maxillary central incisor(11.12±1.37)mm、mandibular central inci-sor(10.15±1.09)mm,mandibular lateral incisor(11.27±1.15)mm and mandibular canine(12.81±1.48)mm be-tween the open bite group and the normal overbite group(P<0.05).On the other hand,the two groups were significant-ly different in crown-root morphology of the maxillary central incisor(1.10°±3.62° vs.4.53°±2.30°,P<0.01)but not in the mandibular central incisor.Conclusion The root length of the maxillary central incisor,mandibular central inci-sor,mandibular lateral incisor,mandibular canine in high-angle Class Ⅱ open bite patients is shorter than that in high-angle Class Ⅱ normal overbite patients,and the long axis of the crown of the maxillary central incisor in high-angle Class Ⅱ open bite patients obviously deviates toward the labial side relative to the long axis of the root.The crown-root angle is smaller,which is beneficial to torque control or adduction movement of the anterior teeth in high-angle Class Ⅱopen bite patients.
9.Cone-beam computed tomography study of root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology in high-angle Class Ⅱ open bite patients
Qingyuan REN ; Lina BAO ; Mengjiao ZHOU ; Chunlan WU
Journal of Prevention and Treatment for Stomatological Diseases 2024;(3):196-201
Objective This study aimed to explore the root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology in patients with high-angle skeletal Class Ⅱ open bite,aiming to provide a refer-ence for clinical treatment.Methods This study was reviewed and approved by the Ethics Committee,and informed consent was obtained from the patients.CBCT images of eighty-one untreated patients(40 anterior open bite patients and 41 normal overbite patients)with high-angle skeletal Class Ⅱ malocclusion were selected before treatment.Dolphin software was used to study the root length of maxillary and mandibular anterior teeth and central incisor crown-root mor-phology,and the differences between the two groups were analyzed.Results There was no statistical significance in the root length of maxillary lateral incisor and canine between the open bite group and the normal overbite group,signifi-cant differences were found in the root length of maxillary central incisor(11.12±1.37)mm、mandibular central inci-sor(10.15±1.09)mm,mandibular lateral incisor(11.27±1.15)mm and mandibular canine(12.81±1.48)mm be-tween the open bite group and the normal overbite group(P<0.05).On the other hand,the two groups were significant-ly different in crown-root morphology of the maxillary central incisor(1.10°±3.62° vs.4.53°±2.30°,P<0.01)but not in the mandibular central incisor.Conclusion The root length of the maxillary central incisor,mandibular central inci-sor,mandibular lateral incisor,mandibular canine in high-angle Class Ⅱ open bite patients is shorter than that in high-angle Class Ⅱ normal overbite patients,and the long axis of the crown of the maxillary central incisor in high-angle Class Ⅱ open bite patients obviously deviates toward the labial side relative to the long axis of the root.The crown-root angle is smaller,which is beneficial to torque control or adduction movement of the anterior teeth in high-angle Class Ⅱopen bite patients.
10.Cone-beam computed tomography study of root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology in high-angle Class Ⅱ open bite patients
REN Qingyuan ; BAO Lina ; ZHOU Mengjiao ; WU Chunlan
Journal of Prevention and Treatment for Stomatological Diseases 2024;32(3):196-201
Objective:
This study aimed to explore the root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology in patients with high-angle skeletal Class Ⅱ open bite, aiming to provide a reference for clinical treatment.
. Methods:
This study was reviewed and approved by the Ethics Committee, and informed consent was obtained from the patients. CBCT images of eighty-one untreated patients (40 anterior open bite patients and 41 normal overbite patients) with high-angle skeletal Class Ⅱ malocclusion were selected before treatment. Dolphin software was used to study the root length of maxillary and mandibular anterior teeth and central incisor crown-root morphology, and the differences between the two groups were analyzed.
Results:
There was no statistical significance in the root length of maxillary lateral incisor and canine between the open bite group and the normal overbite group, significant differences were found in the root length of maxillary central incisor (11.12 ± 1.37) mm、mandibular central incisor(10.15 ± 1.09)mm, mandibular lateral incisor(11.27 ± 1.15)mm and mandibular canine(12.81 ± 1.48)mm between the open bite group and the normal overbite group(P<0.05). On the other hand, the two groups were significantly different in crown-root morphology of the maxillary central incisor (1.10° ± 3.62° vs. 4.53° ± 2.30°, P<0.01) but not in the mandibular central incisor.
Conclusion
The root length of the maxillary central incisor, mandibular central incisor, mandibular lateral incisor, mandibular canine in high-angle Class Ⅱ open bite patients is shorter than that in high-angle Class Ⅱ normal overbite patients, and the long axis of the crown of the maxillary central incisor in high-angle Class Ⅱ open bite patients obviously deviates toward the labial side relative to the long axis of the root. The crown-root angle is smaller, which is beneficial to torque control or adduction movement of the anterior teeth in high-angle Class Ⅱ open bite patients.


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