1.Diagnosis and treatment of traumatic chyloperitoneum
Chinese Journal of Current Advances in General Surgery 2004;0(06):-
Objective:To investigate the proper method for treating traumatic chyloperitoneum. Methods: A retrospective analysis was performed on clinical data of 4 cases of traumatic chyloperi- toneum admitted to our hospital in recent 26 years. Results: All 4 cases were cured after conserva- tive treatment. Conclusion: Perdominantly integrated therapy including absolute diet,total parrenter- al nutrition(TPN) and abdominal cavity drainage can be the effective method for the treatment of trau- matic chyloperitoneum.
2.Biological effects of nonthermal plasma combined with X-ray irradiation on human hepatocellular carcinoma in nude mice
Journal of International Oncology 2017;44(4):257-261
Objective To investigate the biological effects of nonthermal plasma (NTP) combined with X-ray irradiation on human hepatocellular carcinoma in nude mice.Methods By subcutaneous inoculation, tumor models of human hepatocellular carcinoma HepG2 in nude mice were established, and these mice were divided into control group, NTP treatment group, X-ray irradiation group, combined treatment group.The changes of tumor microenvironment were observed using hematoxylin-eosin (HE) staining.The terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) was used to determine the level of neuronal apoptosis in tumor tissues.The expression of metal matrix proteinase-2 (MMP-2) was detected by immunohistochemical assay.Transmission electron microscope was used to observe cell structure changes.Results The final tumor volumes of control group, NTP treatment group, X-ray irradiation group, combined treatment group were (543.96±108.45), (436.54±65.49), (351.66±56.68), (281.97±35.60)mm3, with a statistically significant difference (F=9.63, P=0.01), and the difference between X-ray radiation group and the combination treatment group was significant (P=0.05).HE staining showed that there was a larger area of necrosis in the combined treatment group compared with the other groups.TUNEL showed that the apoptotic indexes were (0.95±0.13)%, (5.82±0.26)%, (7.53±0.43)%, (11.07±0.35)% respectively, with a statistically significant difference (F=547.76, P=0.00), and the difference between X-ray radiation group and the combination treatment group was statistically significant (P=0.00).The immune scores of each group were 12, 9, 9, 2.Electron microscopic observation showed that there were more apoptotic bodies in the combined treatment group than those in the other groups, accompanied by mitochondrial edema.Conclusion NTP and X-ray irradiation therapy in the treatment of human hepatocellular carcinoma in nude mice model has a synergistic effect.Probably, it can be a new type of treatment in curing cancers.
3.Comparison and enlightenment on the general practice education between Britain and Aus-tralia
Chinese Journal of Medical Education Research 2015;(9):884-887
General practice education at higher medical university is the foundation of the general practice educational system. It has close relationship with the cultivation quality of the general practitioners. By taking British and Australian medical colleges as examples, the paper introduced the current situation of British and Australian general practice education for undergraduate medical stu-dents and elaborated their theory learning content, their practice learning content ,their education re-form and research progress and their education target and effect. General practice education in Britain and Australia sheds light on how to set theory course, arrange practice part and improve educational research, which general practice education in China can draw lessons from.
4.Expression of CD38 and HLA -DR on CD +8 T cells in patients with chronic hepatitis B and HBV carriers
Chinese Journal of Primary Medicine and Pharmacy 2015;(18):2836-2839
Objective To determine the expression of CD38 and HLA -DR on CD +8 T cells in patients with chronic hepatitis B and HBV carriers,and to disscuss the relation between immune activation and disease progression of HBV infection.Methods Thirty -two chronic hepatitis B patients receiving adefovir dipivoxil treatment,31 HBV carriers and 28 normal controls were collected.The counts of CD +4 and CD +8 T cells and the percentage of CD +8 CD +38 and CD +8 HLA -DR +T cells were tested by flow cytometry.HBV DNA and liver function were tested in the central laboratory of our hospital.Results The percentage of CD +8 CD +38 T cells in CHB patients was (58.4 ±12.7)%,and was higher than that in HBV carriers (46.8 ±8.5)% and normal controls (46.8 ±8.5)%,and decreased after adefovir dipivoxil treatment (34.2 ±9.4%)(F =8.27,P =0.000).The percentage of CD +8 CD +38 T cells in HBV carriers was (43.3 ±12.5)%,and was much higher than that in normal controls (9.8 ±5.7)%(F =13.48,P =0.000).The percentage of CD +8 HLA -DR + T cells in CHB patients was higher than that in normal controls,but similar to that in HBV carriers (37.1 ±11.3)%.CD +8 HLA -DR + T cells in CHB patients also decreased after adefovir dipivoxil treatment (P <0.05 ).Conclusion Our study demonstrates that activation of CD +8 T cells is increased in HBV infection but decreased by adefovir dipivoxil treatment.The percentages of CD +8 CD +38 and CD8 +HLA -DR +T are good markers for disease progression of HBV infection.
5.Observation of Therapeutic Effect of Compound Glycyrrhizin on Chronic Type B Hepatitis
China Pharmacy 1991;0(04):-
OBJECTIVE:To observe the effect of compound glycyrrhizin on patients with chronic type B hepatitis.METH_ ODS:126patients with chronic type B hepatitis were randomly divided into two groups:the control group was administered with common therapy like reducing jaundice and protecting liver;the trial group was administered with compound glycyrrhizin plus the therapy of the control group.Time of therapy for both groups was8wk.RESULTS:The total effective rates for the tri_ al group and the control group were93.6%and33.3%,respectively,and significant differences were noted between groups(P
6.Direct economic loss incurred by nosocomial infection of inpatients at a tertiary hospital
Chinese Journal of Hospital Administration 2017;33(1):54-56
Objective To investigate the direct economic loss of nosocomial infection at a tertiary hospital, so as to provide data support for the improvement of hospital infection control. Methods Inpatients discharged in 2013-2015 period were divided into two groups at a 1:1 pairing ratio, having those suffering from nosocomial infection in only one occasion as the infection group, and those without as the non-infection group. The two groups were compared of their differences in days of stay and hospitalization expenses. Results The days of stay of the infection group were significantly longer than the non-infection group, averaging 6 days longer in terms of the median. Compared with the non-infection group, the total hospitalization cost and the differences with sub-categories other than the treatment cost were of significance. The costs over the non-infection group were mostly contributed by drugs, accounting for 50. 39%, while 23. 50% of which were spent on antibiotics. The additional antibiotics costs were mainly incurred by respiratory tract infections during hospitalization, as the costs of antimicrobial agents for the infection group were 27. 34 times that of the non-infection group. The second contributor was surgical site infection, with the cost of antibiotics 7. 63 times that of the non-infection group. Conclusions Hospital infections prolong the days of stay, increase direct economic loss, especially increase the cost of antibiotics. Prevention and control of respiratory system and surgical site infection can effectively reduce the direct economic loss of hospital infection.
7.Clinical analysis of 39 cases of pancreatic trauma
International Journal of Surgery 2013;(2):82-85
Objective To explore the key points of diagnosis,treatment and the reasonable surgical methods in 39 cases of pancreas trauma.Methods A retrospective review and analysis the cause and classification of injury,surgical methods of 39 cases of pancreatic trauma in the Department of General Surgery of Affiliated Provinical Hospital of Anhui Medical University during Jan.1990 to Dec.2011.Results In the 39 patients who underwent surgery,38 patients were cured,1 dead duing to craniocerebral injuries,3 patients with complications of pancreatic leakage cured after adequate drainage.Two patients with pancreatic pseudocyst pancreatic pseudocystcyst cured after pancreatic pseudocyst jejunum anastomosis.One patients with traumatic pancreatitis cured after conservative treatment.Conclusions Blunt injury is the most common cause of pancreas trauma.Imaging examination has high value in the early diagnosis of pancreas trauma.The reasonable surgical methods and careful examination during operation can improve the cure rate and reduce the mortality and incidence of complications of pancreatic trauma.If the patient's condition allowed,endoscopy not only contributes to the diagnosis of pancreatic trauma,but is an effective method for treatment of it.
8.A novel classification-coding scheme for medical image retrieval
Chinese Medical Equipment Journal 2003;0(10):-
A novel mono-hierarchical muti-axiel classification coding scheme for medical image retrieval is proposed.The so-called MOAB coding scheme consists of four axes with three to four positions ranging from0to9,from A to Z.In particular,the modality code M describes imaging modality and relevant technical detail,and the orientation code O models examined body orientation.The anatomy code A refers to the body region examined and the biology code B describes the biological system examined.The MOAB classification-coding scheme enables a unique classifi-cation of medical images so that medical image retrieval can be efficient.The code is flexible and easy to be ex-tended.
9.The Effect of Simulated Intensive Military Training on the Na~+,K~+-ATPase in Kidney of Rats
Chinese Journal of Sports Medicine 1982;0(01):-
Objective To study the effect of simulated intensive military training on the activity of the Na+,K+-ATPase in kidney of rats. Methods ① Twenty four rats were randomly divided into single bout of exhaustive exercise group(B) and control group(A).Rats in group B were forced to run on the treadmill until exhaustion according to the Bedford protocol,and their urine and the activity of Na+,K+-ATPase in kidney were tested immediately(B1,n=16) and 24 hours(B2,n=8) after exhaustion.② Another forty rats were randomly divided into 8-week incremental exercise group(D,n=20) and control group(C,n=20).Rats in group D were forced to run on the treadmill according to the incremental protocol for 8 weeks.The urine and the activity of Na+,K+-ATPase in kidney of group C and D were tested by the end of 4th week(C1 and D1) and by the end of 8th week(C2 and D2). Results ① As compared with group A,the values of urinary protein and urease in group B increased and the activity of Na+,K+-ATPase in kidney decreased obviously(P
10.Research of Calibrating Method of Electrosurgical Analyzer
Chinese Medical Equipment Journal 2004;0(08):-
Objective To research the calibration methods of the electrosurgical analyzer which is applied in calibration for production and use of electrosurgical generator. Methods Two methods were put forward,the first one is indirect measurement,the second one is comparing with congeneric device,and these two methods in theory and practice to process real data were analyzed. Results The device with the methods are tested and analyzed,and then,the test error or uncertainty of electrosurgical analyzer is used in analyzing and processing. Conclusion The test error or uncertainty of leakage current and peak factor can also get by these two methods,and these methods could be used as calibration method in production and usage of electrosurgical generator or method for tracing the source.