1.Effects of the supine and prone rest postitions on gastrointestinal pe ristaltic function in premature infants
Chinese Journal of Nursing 2001;36(2):90-91
Objective: To observe gastrointestinal perista ltic function in premature infants in the supine or prostrate post itons .Methods: 24 premature infants were chosen and kept in the supine or pron e positions.Fluid retention volume in the stomach was recorded and compared statistically. Results:The prone group had a lower fluid retention volume.Ther e was a significant difference between the two groups (P<0.001 ). Conculsion:The prone position is a modera te position that improves premature infants' gastrointestinal peristalti c function,digestion and assimilation.
2.Differential effects of morphine on conditioned place preference and locomotor activity in adult and adolescent rats
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(11):979-981
Objective To test whether adolescent rats are more sensitive than adult rats to morphine' s rewarding actions and locomotor activating effects. Methods Conditioned place preference(CPP) procedure was used to examine drug-induced reward and locomotor activity. Adolescent ( Postnatal day 35 ) and adult ( P67 ) male rats received either saline or morphine (3 mg/kg) for 6 days and the locomotor response in the drug paired chamber was recorded during conditioned training. CPP effects were tested 24h after the last training. Results In adolescent rats, morphine CPP effect was not present [ saline group (20. 89 ±31. 14) s, morphine group (90. 75 ± 27.91)s, P = 0. 15], however, morphine CPP effect occurred in adult rats[saline group (31.5 ± 41. 24) s, morphine group(266. 13 ± 32. 26) s, P < 0. 001 ]. Adult rats presented higher CPP score than adolescent rats(P < 0.001). The locomotor response was significantly higher in day 3 ~ 6 than day 1 in the adolescent treated with morphine (P<0.05 or <0. 01). The locomotor response was significantly higher in day 2-6 than day 1 in the adolescent treated with morphine(P<0. 05 or < 0. 01 ) .which suggested that both adolescent and adult rats exhibited similar behavioral sensitization to morphine administration. Two-way ANOVA indicated that the main effect of age was not significant(F_(1,14) =0. 33, P = 0. 57) ,the interaction effect of age x treat was not significant(F_(5,70) = 0.85, P = 0.52) .there was no age difference between adolescent and adult rats in behavioral sensitization effects. Conclusion Compared with adult rats, adolescent rats don' t present morphine CPP, but show the similar morphine behavioral sensitization.
3.Cognitive Processes Bias of Self-referent Encoding Task in Depressive College Students
Chinese Journal of Clinical Psychology 1993;0(01):-
Objective: To test whether depressive college students had sociotropic self-schemata. Methods: A total of 500 college students were surveyed by CES-D and SAS, and 77 college students were chosen for further experiment: 24 with depressive mood, 12 with anxious mood, 17 with both depressive and anxious mood, and 24 normal ones. Sociotropic adjectives were strictly developed, and the 4 groups (depressive vs. anxious vs. depressive and anxious vs. normal) were given Self-referent Encoding Task. Results: ①The depressive group showed significantly less positive adjectives and more negative adjectives for self-descriptive than the normal group (P
4.Recombinant Interferon ?2a Synergistically Enhances SKOV3 Ovarian Tumor Cell Killing by the HSV-tk/GCV System
Yuejuan CHENG ; Lingya PAN ; Yi ZHANG
Chinese Journal of Cancer Biotherapy 1994;0(01):-
Objective: To determine if IFN-?2a and HSV-tk/GCV have synergy on the cell killing of the SKOV3 human ovarian tumor cell line. Methods: hytk gene retroviral vector plasmid was transduced into SKOV3 cells. Both the cytotoxicity and the bystander effect were evaluated after the treatment of GCV. IFN-?2a and HSV-tk/GCV were used together to determine if they have synergy on the tumor cell killing effect, then post-treatment cell cycle analysis was carried out.Results: A dose dependent cell killing of SKOV3/hytk was observed after treatment with GCV. Bystander effect was seen in mixed culture of hytk-positive and -negative cells. Furthermore, IFN-?2a had a significant (P
5.Research on the acculturation of Pakistani medical students in China
Yuejuan ZHANG ; Ling LONG ; Rui LIU
Chinese Journal of Medical Education Research 2012;11(9):981-984
The article analyzed the impact of cultural differences factors and non-cultural factors on cross-cultural adaptation of Pakistani medical students from the following aspects:daily habits,language,religion,values,China's laws and regulations,service mode of social life,curriculum setting,universities' management mode,adolescent growth factors,learning methods and learning ability,higher education and primary education teaching methods,difference between traditional and modern Chinese.Some recommendations were given from several aspects,such as enrollment,management,policy formulation and adolescent education.
6.Treatment effects of trimetazidine on coronary artery bridge
Jianyan ZHANG ; Zhaozeng GUO ; Tao ZHANG ; Xuejiao MA ; Yuejuan CAO
Tianjin Medical Journal 2016;44(7):914-916
Objective To observe the treatment effects of trimetazidine on myocardial bridge. Methods A total of 76 patients with clinical symptoms, such as different degrees of chest tightness, palpitation, breath shortness, chest pain, were diagnosed as coronary myocardial bridge by coronary angiography, and were divided into two groups randomly. While control group (n=40) was given beta-blocker or (and) calcium antagonist as routine treatment. The treatment group (n=36) was given routine treatment and trimetazidine, 20 mg, three times daily. The mean follow-up period was 12 weeks. The episodes of chest pain per week, exercise tolerance, anxiety and depression scores, total ischemic burden in 24 h and walking distance in 6 min were observed in two groups of patients. Results The parameters of chest pain times per week, exercise tolerance, anxiety and depression scores, total ischemic burden in 24 h and walking distance in 6min were improved in treatment group compared with control group, and the symptoms were effectively relieved, the life quality of patients were improved. Conclusion The conventional treatment combined with trimetazidine is safe and effective, which can further improve myocardial energy metabolism and exercise tolerance, and enhance the clinical effect and the life quality of patients.
7.Information security in digital hospitals and its management strategies
Dinghua ZHOU ; Xiaojuan LV ; Lin ZHANG ; Jingtai LU ; Yuejuan WANG
Chinese Journal of Medical Library and Information Science 2015;(6):62-65
Information security is the key in construction of digital hospitals and determines the successful diagno-sis and treatment of diseases in hospitals with information as a tool.The major problems in our hospital were imper-fect information security system , weak technique support , and insufficient implementation of regulations .The infor-mation security can be assured by constructing the security systems-for computer room, networks, data and their management , respectively .
8.Early detection for grafts restenosis after femoro-popliteal bypass grafting
Zhongjie PAN ; Hua ZHANG ; Li LI ; Yuejuan CAO
Chinese Journal of General Surgery 2016;31(4):305-307
Objective To compare the postoperative follow-up indexes of femoral popliteal artery bypass grafts and evaluate the sensitivity of vessel function test methods for the early detection of grafts restenosis.Methods 84 cases were followed-up after femoral popliteal graft bypass,using ankle brachial index (ABI),ABI decrease amplitude,and Duplex ultrasound to detect peak systolic velocity (PSV) and peak systolic velocity ratio (PSVR).All patients were divided into mild stenosis group (0-49%),moderate stenosis group (50%-74%) and severe stenosis group (75%-99%).Results ABI was 0.88 ±0.12,0.81 ± 0.10 and 0.52 ± 0.13;ABI decrease amplitude was 0.13 ± 0.06,0.12 ± 0.06 and 0.36±0.06;PSV(m/s) was 0.89 ±0.23,0.91 ±0.31 and 1.70 ±0.85,respectively.There was remarkable difference for ABI,ABI decrease amplitude and PSV between severe stenosis and mild to moderate stenosis group (P <0.05).PSVR was 1.00 ±0.08,2.14 ±0.31 and 3.58 ±0.31 respectively,in the three groups (P < 0.05).Conclusion PSVR was more sensitive to detect grafts restenosis early than ABI,ABI decrease amplitude and PSV.
9.Endoscopic mucosal resection for gastrointestinal neuroendocrine tumors with diameter≤10mm: a retrospective analysis of 40 cases
Lei XIN ; Li WANG ; Hao WANG ; Yuejuan ZHANG
Chinese Journal of Endocrine Surgery 2021;15(1):94-97
Objective:To investigate the safety and reliability of endoscopic mucosal resection (EMR) in the treatment of gastrointestinal neuroendocrine tumors (GI-NETs) with a diameter of ≤10mm.Methods:From February 2015 to June 2019, 40 cases of gastrointestinal neuroendocrine tumors with a diameter of ≤10mm underwent EMR in Yantaishan Hospital of Yantai City were retrospectively analyzed to evaluate the safety and reliability of EMR surgery.Results:All 40 cases were performed endoscopically by EMR. The en bloc resection rate and RO resection rate reached 100%. The lesions were all confined to the submucosa and did not infiltrate the muscularis propria. Postoperative pathological classification: NET G1: 35 cases, NET G2 grade: 5 cases, no NET G3 grade cases. There were no complications such as bleeding and perforation during and after the operation. Follow-up: 1 case was lost to follow-up, 1 patient died of other diseases, and the remaining 38 cases were followed up for an average of 27.8 months (5-46 months) without local recurrence or distant metastasis.Conclusion:For well-differentiated G1 and G2 gastrointestinal neuroendocrine tumors with a diameter ≤10mm, EMR is a safe and reliable treatment.
10.Criterion-related validity of the competency model of armed police sergeant
Yuejuan ZHANG ; Jinli WANG ; Lisa DUAN ; Xiang SUN ; Pengfei CAO
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(8):740-742
Objective To examine the Criterion-related validity of the competency model of armed police sergeant.Methods 513 armed police soldiers were evaluated by 2 leaders with competency model of armed police sergeant.5 equidistant grades rating method was used.The list of excellent soldiers were collected.Results ( 1 ) There were significant differences on 17 items of competency scores between excellent soldier group and average soldier group (P < 0.05 ), except for one item of competency.Furthermore, there were significant differences on 4 factor scores and sum scores between excellent soldier group and average soldier group (P < 0.05 ).( 2 ) The predictive probability were 72.6 % (A) ,71.3% (B) predicting excellent soldiers by the sum scores of competency model.Conclusion The Criterion-related validity of the competency model of armed police sergeant is acceptable.It can be used in the selecting and training of armed police sergeant.