Objectives To observe the co-activation phenomenon during exercise fatigue induced by the proximal muscles on the upper limbs.Methods Sixteen undergraduates not majoring in sports participated in this study,and their left arms were chosen as the observed arms and right arms were selected as the weighted arms.The weighted arm was alternatively in the state of relaxation without any load and fatigue after bending and extending elbow joints to uphold a 5 kg dumbbell.However,the observed arm kept weighing a 4 kg dumbbell with 90 degrees elbow flexion until the muscles were exhausted.The surface electromyography of biceps brachii and triceps brachii of the observed arms was measured using the ME6000.And the integrated surface electromyography (IEMG),root of mean square (RMS),mean power frequency (MPF)and median frequency (MF)were further analyzed.Results The IEMG and RMS of biceps brachii and triceps brachii of the observed arms increased gradually after the exercise began (P＜0.05)regardless of in the relaxed state or in the in the state of weighing a 5 kg dumbbell for the weighted arm,but in the state of weighting a 5 kg dumbbell the IEMG and RMS increased more significantly (P＜0.01),Meanwhile the electrical activities of the triceps brachii as an antagonistic muscle were intensively inhibited.The changes of MPF and MF of biceps brachii in the observed arms were more significant in the state of exercise fatigue than in the relaxed state (P＜0.01),but without such an impact on the triceps brachii.Conclusions The fatigue in one arm can trigger contingent changes in sEMG time domain and frequency domain indexes of its contralateral parallel muscles,suggesting that sEMG changes of upper limb proximal muscles have the co-activation effect.

The experiences and characteristics of professor ZHANG Yu-lian in regulating marrow sea acupuncture for treatment of post-stroke ataxia is introduced. Professor ZHANG established regulating marrow sea acupuncture based on the fundamentals of traditional Chinese medicine combined with brain functional region projection and cerebrovascular distribution of modern medicine. "Three acupoints regulating balance" "3 acupoints regulating transportation" "3 acupoints regulating tremor" and Fengchi (GB 20), Fengfu (GB 16), Wangu (GB 12), Tianzhu (BL 10) and C3-C6 Jiaji (Ex-B2) acupoints were applied in this kind of manipulation. We combined holding spirits of doctor and patient together, and controlled the sensation transduction with different manipulations to reach the foci, which emphasis on the doctor-patient cooperation and body-mind co-regulation, finally promote patients' comprehensive rehabilitation.
Acupuncture Points ; Acupuncture Therapy ; history ; methods ; Ataxia ; etiology ; history ; therapy ; China ; History, 20th Century ; History, 21st Century ; Humans ; Stroke ; complications

Congresses as Topic ; Humans ; Hypersensitivity, Immediate ; immunology ; Rhinitis ; immunology

Incidence and mortality of colorectal cancer has increased significantly in recent years. Screening for colorectal cancer is the most effective method to decrease mortality. Colorectal adenoma is the precancerous lesion of colorectal cancer and can be detected through colonoscopy, which is the crucial in the early diagnosis and early treatment for colorectal cancer. The first step of screening is the selection of target population and the second step is colorectal examination. The selection of candidate for screening has direct effect on the efficacy of screening. The methods in common use include fecal occult blood test, questionnaire for high risk factors of colorectal cancer, colonoscopy, sigmoidoscopy, and CT virtual colonoscopy. Among those, colonoscopy is the most reliable method and widely used in the screening for colorectal cancer.
China ; Colonoscopy ; Colorectal Neoplasms ; diagnosis ; Early Detection of Cancer ; methods ; Humans ; Mass Screening ; methods ; Occult Blood

Antibodies, Monoclonal, Humanized ; administration & dosage ; Antineoplastic Combined Chemotherapy Protocols ; therapeutic use ; Bevacizumab ; Capecitabine ; Chemotherapy, Adjuvant ; Colonic Neoplasms ; drug therapy ; surgery ; Deoxycytidine ; administration & dosage ; analogs & derivatives ; therapeutic use ; Disease-Free Survival ; Fluorouracil ; administration & dosage ; analogs & derivatives ; therapeutic use ; Humans ; Leucovorin ; administration & dosage ; Organoplatinum Compounds ; administration & dosage ; Semustine ; therapeutic use ; Survival Rate ; Vincristine ; therapeutic use

Objective:To discuss the anti-rheumatoid arthritis activity and mechanism of hospital preparation Erteng Tongbi gran-ule ( ETTB) . Methods:The collagen-induced arthritis ( CIA) animal model in DBA/1 mice was established and treated with high, medium and low dosage of ETTB. Blank control, model control and methotrexate group were also established. The influences of ETTB on BMI, arthritis index, ankle joint destruction and expression of serum cytokine TNF-α and IL-6 in CIA mice were observed. Re-sults:Compared with the control group, ETTB at high dose (6g?kg-1) could significantly decrease the arthritis index of CIA mice (P<0. 05), and the joint damage on the 14th day was also significantly improved. ELISA results showed that ETTB at high dose could significantly inhibit the secretion of cytokine TNF-αand IL-6 when compared with the model group (P<0. 01). Conclusion:Hospital preparation ETTB has anti-rheumatoid arthritis activity, and its mechanism may be related with the inhibition of cytokine secretion.

TED-Med Viewing, Listening&Speaking is compiled to serve academic audio-visual-oral English teaching in medical colleges. This paper elaborates some compilation ideas concerning this text-book. First, both the urgent needs of academic English teaching and the unique advantages of TED speech are the major stimulus to compiling this textbook. Second, its compiling philosophy adheres to learning centered, meaningful input. Third, compiling process is divided into three stages-preparation, writing and evaluation. Third, compiling principles includes four aspects: language and medical knowledge integrate
organically, the text and the task are authentic; proficiency training approaches are scientific; and the text-book is suitable for autonomous learning. Forth, the main content covers four medicine-related themes-humanity, health, disease, science and technology; each theme consists of three sub topics with 12 units (topics) in total; the content is interesting, informative and reflective. These compilation ideas prove to be scientific and feasible demonstrated by English teachers and medical experts. TED-Med Viewing, Listening&Speaking is expected to be completed and published earlier in order to promote academic English teach-ing and research in medical colleges.

Objective To study the clinical efficacy of fondaparinux sodium in the treat of deep vein thromboembolism after the surgery on lower limbs.Methods 83 cases of patients with lower extremity surgery from Jan 2013 to May 2015,were randomly divided into experimental group(42 cases) and control group(41 cases),the patients in experimental group were injected subcutaneously with fondaparinux sodium 2.5 mg,one time a day,for five days and the patients of control group administrated orally with rivaroxaban 10 mg, one time a day, for five days.All patients accepted the ultrasonic examination by Doppler’ s method before the experiment, seven days and one month later after the experiment.The occurrence of deep vein thromboembolism of all patients was counted,including Proximal thrombosis,Distal thrombosis and Total venous thrombosis,and recorded the occurrence of adverse reaction-subcutaneous hemorrhage.Results One case(2.38%)of deep vein thrombosis was appeared in the experimental group,and that was significantly lower than that of the control group seven case ( 17.07%, P <0.05 ) .Meanwhile, there was no patient observed adverse reaction in experimental group, while two cases were observed in control group ( P <0.05 ) .Conclusion Fondaparinux showed better clinical efficacy than rivaoxaban,and caused fewer adverse reaction.We can conclude that it is safe and effective for the treatment of deep vein thrombosis in patients accepting the lower limbs surgery.

Objective:To investigate the inhibitory effects of human angiostatin ( AS) on the subcutaneously transplanted mouse glioma. Methods; Effects of AS on the proliferation of angioendothelial cell line ECV-304 and human glioma cell line TJ-905 were observed with MTT method. Mouse model of subcutaneously transplanted of glioma line G422 was established. AS was injected subcutaneously, tumor ratio and tumor in hibitory rate were estimated. Results; ( 1) Inhibitory effects of AS on ECV-304 enhanced with the increase of dose, while AS exerted no effect on TJ-905 ; (2) It was shown with animal experiments that turner inhibitory rates were 21. 8% and 84. 3% with AS doses of 10 mg and 50 mg-kg-1. d-1 , respectively; (3) Immunochemical factor VM staining indicated there the differences between the control and the control and the test groups in both the angiodevelopment and quantity. Conclusion; There was no inhibitory effect for AS to angiolorna cell in vitro, however in vivo, it inhibited the glioma growth via its inhibitory effect on the proliferation of an-gioend othelial cell line. It was then suggested that AS would be of wide application in tumor treatment.

Objective To investigate the clinical value of combined detection of anti-cyclic citrullinated peptide antibody(anti-CCP antibody),rheumatoid factor(RF),C-reactive protein(CRP)and erythrocyte sedimentation rate(ESR)in the diagnosis of rheu-matoid arthritis(RA).Methods The detection results of the four serum indicators of 290 cases of patients with RA(RA group), 286 cases of patients with non-RA autoimmune diseases(non-RA group)and 1 50 cases of healthy individuals(control group),from March 2013 to August 2014 in this hospital,were retrospectively analysed.Results The serum levels of the four indicators have significant differences among the three groups,between the RA group and non-RA group,and between the RA group and control group(P =0.000).Between non-RA group and control group,there was significant difference of serum levels of anti-CCP antibodies (P =0.013),while the other three serum indicators had no significant differences (P >0.05).The sensitivity of combined detection of anti-CCP antibody and RF,combined detection of anti-CCP antibody,RF and CRP,combined detection of anti-CCP antibody,RF and ESR,and combined detection of anti-CCP antibody,RF,CRP and ESR for RA diagnosis have statistically significant differences (P <0.05),while there was no statistically significant differences of specificity (P > 0.05 ).The area under a receiver operating characteristic (ROC) curve of anti-CCP antibody,RF,CRP and ESR were 0.873,0.893,0.678 and 0.747,respectively. Conclusion Combined detection of anti-CCP antibody and RF has good specificity and sensitivity,which could improve the clinical diagnosis of RA.Combined detection of CRP and ESR could improve the detection rate of RA.