"Humanity and virtue" is the core of Chinese traditional medicine ethics.The theories of "medicine is humane art" and "curing people with benevolence" were emphasized by Chinese doctors through the ages.According to the theory of the ancient doctors,the connotation of "humanity" is rich and profound,which is mainly embodied in two aspects-"humanity and virtue"of physicians and medical morality.The analysis and inheritance of "Humanity and virtue"of traditional Chinese medicine is of great signi cance for the construction of modern medicine.

Objective]To summarize and clarify the view on Yin and Yang of Zheng Qin-An ,in order to deepen the study on fire-spirit school. [Method]Read the related works of Chen Xiu-Yuan, Liu Yuan, Zheng Qin ’An, Lu ZhuZhi, etc, as wel as related research papers of modern researchers. Then we summarize the view on Yin and Yang of Zheng Qin-An, as wel as it ’s resources and evolution. [Result] Zheng Qin-An advocated the balance of Yin and Yang, didn’t admire Yang and despise Yin. He also had no preference on Yang aided medicine. Zheng Qin-An ’s view on Yin and Yang mainly was affected by Liu Yuan, and significantly different from Chen Xiu-Yuan. Lu Zhu-Zhi inherited the academic point of view of Zheng Qin-An and made some significant changes. After that, fire-spirit school only emphasized the importance of Yang Qi. Developed to the extreme, some fire-spirit school scholars held that al patients were Yang deficiency and al prescriptions should aid Yang Qi. These views had deviated significantly from its founding fathers. [Conclusion]Zheng Qin-An advocated the balance of Yin and Yang, but his successor ’s only emphasis on the importance of Yang Qi, was contrary to the original intention of Zheng Qin-An.

Seven Compounds were isolated from dry Radix of Lindera reflexa.They were identified as lauuobine (Ⅰ ), lindcarpinc (Ⅱ), laurolitsiuc (Ⅲ), ?pinostrobin (Ⅳ), ?pinocembrin (Ⅴ),octacosanoic acid (Ⅵ) and ?-sitosterol (Ⅶ ) on the basis of chemical and spectral aualyses.

Objective] Discuss the“five seasonal organs”theory of The Inner Canon of Huangdi, especially the seasonal issues of the spleen and preliminarily speculate the formation period. [Methods]By means of literature and historiography methods, information before The Inner Canon of Huangdi would be gathered, especially“The Book of Rites·on Order”,“Guanzi·Seasons”,“Annals by Lv·Twelve Ji”and so on. On this basis, we can discuss the different perspectives of “five seasonal organs”theory and the seasonal issues of the spleen of The Inner Canon of Huangdi, and preliminarily speculate the theory’s origin, evolution, and formation. [Results]“Six periods connected to six internal organs”theory is more concerned with the meaning of anatomy, although it is early view of the“seasonal organs”theory, but six or twelve has its specific cultural origins;“Eight wind connected to eight internal organs”theory is affected by Zhou Yi;“four periods connected to four internal organs”theory couldn’t explain attribution of the“soil”and its role, it belongs to the early stages of Qi argumentation of the“seasonal organs”theory after the introduction of the Five Elements Theory;“five periods connected to five internal organs”theory reflected the tight integration with the theory of five elements and balanced attachment features; the theory which has the most theoretical and clinical meaning is“four periods connected to five internal organs”theory. [Conclusion] The different perspectives of“five seasonal organs”theory and the seasonal issues of the spleen of The Inner Canon of Huangdi are results of a number of philosophical thoughts absorbed by different doctors, but through analysis of the relevant literature, the core ideas can be briefly summarized, it can be generalized that the spleen is located in the center, connected at any time, behalf of governance after each season ’s eighteen days.

Academic circles invariably have diverging view on "incantation and psychology",and differ to pass judgment on it.The author of this article tries to discuss the essential discrepancy of "incantation and psychology" compared with pseudoscience and anti-science from the essence of "incantation and psychology" and its effects in that history stage.It could be said that "incantation and psychology" was a stagger step of the ancients on the road of medical science.It was the confluence of primitive religion,experience and rationality ingredient.So we could not break away from its existing soil to evaluate it striding over the space-time,otherwise it was a discrepancy with historical materialism.Therefore it has practical importance in modern clinic to apply the "incantation and psychology",though excavating the essence of it and endowing it scientific methods.

Objective To discuss the curative effect and functionary mechanism of intraparotid injection on Sjogren’s syndrome (SS), validate the action of restoring the parotid configuration destroyed by immunoreaction and protecting unspoiled parotid, testify the action of improving the function of parotid excreting saliva by intraparotid injection. Methods Patients diagnosed as SS were divided into control group and treatment group. The patient of two groups were all treated by the same dosage hormone and Runzaoling capsule, at the same time, the treatment group were added the intraparotid injection. The parotid configuration, morphologic manifestation and functional melioration were observed. Result There was remarkable difference about the change of parotid configuration (t=1.67, P

Objective To investigate the diagnosis and treatment of acute intestinal obstruction in aged patients over 80.Methods Data of 151 patients over 80 with acute intestinal obstruction admitted from January 2010 to March 2014 were retrospectively analyzed.Results 136 of 151 cases were mechanical intestinal obstruction,including 95 cases of adhesive ileus,13 cases of tumorous ileus,11 cases of bezoar ileus,4 cases of abdominal internal hernia,3 cases of intestinal volvulus,2 cases of incarcerated oblique hernia,1 cases of duodenal stenosis,1 case of sigmoid stenosis,1 case of anastomotic obstruction after radical resection of rectal cancer because of barium,the cause of ileus was unknown in 5 cases.14 of 151 were dynamic obstruction and 1 of 151 was vascular intestinal obstruction.Conservative treatment was performed in 114 cases and 1 patient died.30 cases received operation,including 14 cases of enterodialysis,6 cases of enterostomy,4 cases of enterotomy,3 cases of enterectomy,1 case of right hemicolectomy,1 case of reduction of volvulus of intestine,1 case of gastronesteostomy,and 1 patient died.7 of 151 were against-advice discharged.12 cases of complications occurred after surgery,including 5 cases of incisional wound infection,2 cases of heart failure,1 case of pulmonary infection,1 case of anastomotic fistula,1 case of infective shock,1 case of early postoperative inflammatory bowel obstruction and 1 case of postoperative delirium.Conclusion Adhesive ileus is the most common cause in aged patients over 80 with acute intestinal obstruction.Rational treatment should be carried out according to different conditions.Conservative treatment is often performed and with active perioperative management,most patients will have satisfied results of surgery.

Objective To explore the effect of nicotinaide nucleotide transhydrogenase(NNT) mutation on glucose homeostasis in C57BL/6 mice with mix background. Methods We generated wild type NNT homozygous, mutant NNT homozygous and heterozygous by mating the C57BL/6J (with NNT mutation) and 6N (without NNT mutation). At the age of 4 weeks, those mice were randomly assigned to normal control diet(NCD) or high-fat diet(HFD) for 4 weeks. The body weight was measured every week. At the age of 8 weeks, an intraperitoneal glucose tolerance test(IPGTT) and an intraperitoneal insulin tolerance test (ITT) were performed. Results The body weight growth was not affected by NNT mutation during an HFD fed. NNT mutant mice showed significant glucose intolerance. After 4 weeks of high fat diet, the NNT mutant mice showed a decreased insulin sensitivity, while the glucose excursion curve was not elevated in the heterozygous mice. Conclusion NNT mutation had a significant influence on the phenotype of glucose metabolism and insulin resistance of mice, in particular under a metabolic stress. The phenotypes of heterozygous and homozygous mutant ones differed from each other. When using mice with C57BL/6J and C57BL/6N mixed background in research, NNT mutation should be carefully screened in all metabolic studies.

Photodynamic therapy (PDT), because of its good targeting, minimal invasion, and safety, is becoming a very active area in cancer prevention and treatment, in which the photosensitizers have proved to be the core element for PDT. We developed a new HPLC method for analyzing porphyrin photosensitizers using Shiseido Capcell PAK C18 (150 mm x 4.6 mm, 5 µm) as the column at 30 °C, methanol-1% aqueous solution of acetic acid as the mobile phase in a flow rate of 1.0 mL · min(-1) in a gradient elution mode, and the detection wavelength at 380 nm. This method, showing good specificity, precision, accuracy and robusty via methodology validations, can be applied to the purity test and assay of porphyrin photosensitizers, and has played a key guide role in the R&D of the new porphyrin photosensitizer--sinoporphyrin sodium.

Through combing and analysing the Silk Texts of Hand-Foot-11-Channels by Moxibustion （《足臂十一脉灸经》） and Yin-Yang-11-Channels by Moxibustion （A and B） （《阴阳十一脉灸经》） unearthed from the Mawangdui Han Tomb， the second part of The Book of Vessels （《脉书》） unearthed from the Zhangjiashan Han Tomb， The Vessels Book-Second Part （《脉书·下经》） in Tianhui medical bamboo slips and the fragmentary text of the Channels （《经脉》） and the painted channel portrait unearthed from the Laoguanshan Han Tomb， and the lacquered wooden human body's model of channels unearthed from the Shuangbaoshan Han Tomb， it is argued that the channels starts from the arm jueyin channel which was missing in the early literature of channels， instead of the the hand jueyin pericardium channel， and then argues progressively. It is proposed that the arm jueyin channel in the early meridian literature may have been purposely omitted， that the three yin and three yang paradigms that prevails nowadays has experienced the interchange of the positions of taiyin and jueyin， and that the correspondences between visceral manifestation and the three yin and three yang are derived from the channels theory， and that the pericardium corresponds to the solid organ of the heart， and that the cognitive model of the channels theory has been briefly analysed， which can provide references to the related research.