1.A personal view on the functional and administrative role of medical engineering
Chinese Journal of Hospital Administration 1996;0(07):-
The rapid development of modern science and technology pushes mdeical progress.Med- ical engineering makes its first appearance with the development of medicine.It certainly exercises a pos- itive effect on the quality of medical treatment,nursing service and medical research.The development of science and technology calls for strengthening the construction of medical engineering which is to play the role of obtaining informatioon on medical instruments and equipmient,working out purchase plans, taking charge of installations,checking contracted purchases of goods and services before acceptance, making records,starting a good job of quantified administration,and technically guiding the operation of equipment.Both the society and the unit concerned may be highly benefited through tightening the con- trol of equipment purchase,cost recovery and depreciation.
2.The study on super selective hepatic artery embolization for effects of hepatic cyst volume and liver function of symptomatic patients with polycystic liver
China Medical Equipment 2016;13(8):57-59,60
Objective:To investigate the super selective transhepatic arterial embolization (TAE) for effects of cyst volume and liver function in patients with symptomatic polycystic liver disease (PLD), and provide a reliable basis for clinical diagnosis and treatment. Methods: 14 cases of symptomatic patients with PLD were selected from October 2014 to October 2015 in our hospital using super selective hepatic arterial embolization. The upper abdomen was performed CT scan one year after surgery, and the volume of patients with liver cyst was tested. We observed the changes of total volume of liver before TAE and postoperative kidney function, adverse reactions, and the improvements after four months’ follow-up.Results: The angiography for the 14 patients showed liver volume increased in different degrees. It also showed that blood supply was mainly hepatic artery wall branch. There were different sizes of liver round unstained area. There was consistent between CT examination and unstained area in polycystic liver swollen area. The difference of the total volume of the liver cyst was statistically significant in 14 cases of the patients with PLD before TAE treatment and after 12 months’ treatment (t=2.8627,P<0.05). 14 cases of the patients with PLD after TAE before treatment and after 1 week’s laboratory tests, the difference was not statistically significant among AST, ALT, ALB and TBIL (t=0.0441,t=0.3316,t=0.0722,t=1.9855;P>0.05). Compared with the preoperative, there was little effect on liver function by TAE. After 3 to 12 months, symptoms gradually improved and physical rating increased. The improvement rate was 100% after 12 months and the physical score was from 90 to 100 points. The embolism syndrome in 14 cases of patients gradually disappeared after 1 to 5 days, and five days later the symptoms disappeared. Conclusions: There is a significant effect for symptomatic polycystic liver patients with TAE. It can improve efficacy and reduce patient suffering with a low recurrence rate. It is worthy of clinical application.
3.Originative Malignant Tumors of the Female Internal Genitals:The Analysis of CT and Ultrasonography
Journal of Practical Radiology 1992;0(11):-
Objective To evaluate the value of CT and ultrasonography in the diagnosis of originative malignant tumors of the female internal genitals.Methods 147 cases of originative malignant tumors comfirmed pathology in the female internal genitals were restropectively analyzed.Among them,73 cases were examined by CT.The CT findings were analyzed and compared with ultrasonography.Results Ultrasonography was proved to be slightly superior in the rate of definite diagnosis and also the cost was lower than CT.Conclusion The authors recommend that ultrasonography examination may be used as screening method for the orignative malignant tumors of the female internal genitals,and CT may be used as a important complementary method.
4.Rehabilitation treatment of osteoarthritis with osteoporosis
Chinese Journal of Tissue Engineering Research 2001;5(8):18-19
There is a close relationship between osteoporosis and osteoarthritis .The joints of bearing weight often suffer the osteoarthristis with osteoporosis .There are some symptoms in the disease ,such as pain and motion disorder ,and joint abnormality in late+ stage .The principle of rehabilitation is to improve osteoporosis , release pain and increase the function if motion .The treatment includes medicament ,acupuncture ,injection ,rehabilitation ,psychology and surgery therapies .The injection can release pain effectiverly .The methods of rehabilitation include physical therapy,exercise ,massage ,and occupational therapy.These therapies can release pain ,improve motion and increase the quality of life .The article reveiws the clinical symptoms ,diagnosis and treatment ,especially the rehabilitation therrapy.
5.Effect of intrathecal injection with Rocephin on intracranial infection
Jianhong ZHANG ; Jianzhong FAN
Chinese Journal of Rehabilitation Theory and Practice 2005;11(4):286-287
ObjectiveTo observe the effect of intrathecal injection with Rocephin on intracranial infection after traumatic brain injury.Methods12 patients with intracranial infection after traumatic brain injury were treated with Rocephin, including Rocephin 2.0g vein injection twice a day and 0.1 g intrathecaluse once a day. The germiculture and drug sensitivity test were made before the treatment and antibiotic was selected.ResultsThere were 6 cases recovered, 2 cases improved markedly, 1 case improved and 3 cases unchanged. The efficient rate was 66.7%. The examination of cerebrospinal fluid showed that the levels of leucocyte and protein decreased, the glucose and chloride increased and encephalic pressure declined. 12 bacteria were verified in 12 cases and 8 bacteria were eliminated after treatment. The bacterium cleared rate was 66.7%. There were no side effects correlatives with Rocephin.ConclusionVein and intrathecal injection with Rocephin is effective on intracranial infection after traumatic brain injury.
6.Exploration of clinical training programmes for residents in rehabilitation medicine
Jianhong ZHANG ; Jianzhong FAN
Chinese Journal of Rehabilitation Theory and Practice 2000;6(2):81-84
现代康复医学20世纪80年代初在我国刚刚起步,康复科住院医师培训有待规范化、科学化。本文就康复医学住院医师培训的原则、实施方案进行初步探讨。
7.ABRO1 and its research progress
Jing XU ; Xiaoming YANG ; Jianhong ZHANG
Military Medical Sciences 2015;(2):147-149
ABRO1 (Abraxas Brother 1), known also as KIAA0157 or FAM175B, is an important component of BRISC deubiquitinating enzyme ( DUB) complex which specifically shears K-63 linked polyubiquitin chains .This article reviews the research progress in ABRO 1 in terms of its structural characteristics , BRISC complex composition , the regulation of DUB activity and interferon response , oxidative stress response and anti-myocardial ischemia and provides new ideas on fur-ther study of the physiological function of ABRO 1 and its association with immune and cardiovascular diseases .
8.Efficacy of Mirtazapine and Sertraline in the Treatment of Depression with Anxiety Symptoms
Zuoming CHEN ; Jianhong ZHANG ; Zhanwen LI
Chinese Mental Health Journal 1991;0(05):-
0.05) in treating depression symptoms, but the marked effective rate of mirtazapine group and sertraline group were 78.8% and 43.6% (P
9.Protective effect of naomaitong injection against global cerebral ischemia reperfusion injury in rats
Shide SHI ; Jianhong SHI ; Farong ZHANG
Chinese Journal of Tissue Engineering Research 2005;9(29):235-237
BACKGROUND: Naomaitong injection is a Chinese herbal compound preparation for treatment of ischemic cerebral vascular disease, acting on resisting calcium overload, regulating the imbalance between thromboxane (TXA) and prostaglandin (PG) and blocking lipid peroxidation mediated by free radical so as to protect cerebrum.OBJECTIVE: To observe the effects of naomaitong injection on water and Ca2+ contents, activity of superoxide dismutase (SOD), levels of lipid peroxide (LPO), 6-keto-PG lα and TXA, and compare it with danshen injection.DESIGN: Randomized control experiment was designed.SETTING: Experimental Center of Chengdu University of Traditional Chinese Medicine.MATERIALS: The experiment was performed in Experimental Center of Chengdu University of Traditional Chinese Medicine from October 1997 to February 1998, in which, 72 healthy male Wistar rats were employed, rangroup: Abdominal injection was done with physiological saline 1.67 mL/kg,group): Abdominal injection was done with compound danshen injection groups (naomaitong No.1, No.2 and No.3 groups): abdominal injection was done with naomaitong injection 3.33, 1.67, 0.84 mL/kg successively,twice/day.METHODS: Totally 48 hours after medication, under anesthetized state,the rats in every group were sacrificed to collect brain tissue. The two hemispheres were cut into two pieces from the middle. One of them was prepared into brain tissue homogenate at low temperature. Radioimmunologic analysis method was used to measure 6-keto-PG 1o and TXA B2 levels so as to evaluate the balance between PG and TXA systems. The modified pyorgallol autoxidation and thiobarbituric acid (TBA) colorimetric method were applied to determine SOD activity and LPO level respectively so as to evaluate lipid peroxidation mediated by free radical. The dry and wet weights of other piece were weighed immediately on electronic scale and the water content of brain tissue was calculated to evaluate brain edema. Atomic absorption spectrophotometry (AAS) was used to determine Ca2+content in brain tissue so as to evaluate calcium overload.tissue of rats in every group.content in brain tissue of rats in every group: That in model group was higher remarkably than normal group [(82.27±1.32)%, (77.24±1.36)%;(267.47±15.69), (37.55±13.23) μg/g, P < 0.01]. The water contents in 4 treatment groups were decreased of various degrees. The effect in No.1 group was the strongest [(78.74±1.41)%] and that in danshen group was the weakest [(81.45±1.52)%]. Ca2+ content in danshen group was decreased of various degrees, indicating dose-effect dependence, but, which was near to ty and LPO level in brain tissue of rats in every group: SOD activity in model group was lower remarkably than normal group [(86.18 ±3.17),(131.86±4.67) μkat/g, P < 0.01]. After treated with naomaitong of 3 dosages, that was all improved, indicating dose-effect dependence (P < 0.01). The effect of No.1 group was the strongest [(119.02±4.00) μkat/g],SOD activity in danshen group was near to model group (P > 0.05). LPO level in model group was higher than normal group [(52.46 ±3.25),(32.29±2.23) μmol/L, P < 0.01]. LPO level of every treatment group was lower significantly than model group and the therapeutic effects of No. 1, 2,3 groups were superior to danshen group [(35.68±2.86), (41.54±2.47),1α and TXA B2 in brain tissue of rats in every group: Content of 6-ketoPG 1α in brain tissue of model group was lower remarkably than normal group (P < 0.01). That was improved in all of 4 treatment groups, in which,the therapeutic effects of No.1, 2, 3 groups were superior to danshen group [(43.84±2.98), (35.01±4.32), (29.97±3.81), (22.89±3.64) ng/g, P < 0.01].TXA B2 content in brain tissue of model group was higher remarkably than normal group (P < 0.01). After treatment, the 4 treatment groups lowed significantly TXA B2 content in brain tissue compared with model group,indicating dose difference. That in danshen group was lower than No. 1, 2,3 groups [(40.58±1.34), (32.85±1.43), (34.31±1.39), (37.27±1.52) ng/g, P <0.01].CONCLUSION: Naomaitong injection alleviates brain edema, resists calcium ion, regulates imbalance between TXA and PG systems, improves activity of anti-oxidase and is against injury of free radical so as to protect the structure of brain tissue and achieve therapeutic effects, indicating a certain dose-effect relationship. The effect of naomaitong injection is superior to that of compound danshen injection.
10.The Effect of Cilazapril on the Motor and Cognitive Function in Cerebra l Infarction with Hypertension.
Jianhong ZHANG ; Jianzhong FAN ; Zhencai WANG
Chinese Journal of Hypertension 2001;9(1):41-43
Objective To explore the effect of cilazapril on motor and cognitive function in hypertension with brain stroke. Method 42 hypertensive patients with stroke were divided into cilazapril treatment group(22 cases) and traditi onal treatment group (20 cases). The cilazapril group was treated with Inhibace 2.5 mg~5 mg daily. The traditional group was treated with nifedipine and/or di uretic. The blood pressure was measured twice a day during the treatment course. The activity of daily living (ADL), motor and cognitive function were assessed with Barthel index, Fugl-Meyer and MMSE assessment respectively before and 6 we eks after treatment. Results There were no difference between the two groups on blood pressure effectiveness, but blood pressure was more stable in the cilazapril gro up. Improvement of ADL and lower limb motor function in cilazapril treatment gro up were improved significantly than those of traditional treatment group(P<0.05). Although there was no difference between the two groups in the total value of cognitive function assessment, but the directional ability and memory function in group wa s higher than those in traditional group (P<0.05). Conclusion Cilazapril can decrease blood pressure steadily and can improve the activity of daily living and cognitive function in stroke patients.