1.Advances in the Treatment of Multiple myeloma
Journal of Kunming Medical University 2016;37(10):1-4
Multiple myeloma is a monoclonal plasma cell malignant proliferative disease,accounting for about 10% of malignaut tumors of blood system.In recent years,due to the application of hematopoietic stem cell transplantation and the application of MDT by combining new drug such as thalidomide,lenalidomide and bortezomib,the average survival of MM patients was significantly longer than before.The treatment strategy should be individualized before treatment according to the patient's age,physical condition and complications.In this paper,the treatment strategy of multiple myeloma patients were reviewed.
2.Clinical observation of combined lensectomy with vitrectomy, retaining the peripheral anterior lens capsule
International Eye Science 2014;(9):1689-1690
To investigate the curative effect of retaining the peripheral anterior lens capsule combined lensectomy with vitrectomy for ocular trauma.
●METHODS: Totally 33 patients ( 33 eyes ) with eye trauma underwent combined lensectomy with vitrectomy, retaining the peripheral anterior lens capsule and phase Ⅱposterior chamber lOL implantation. After follow - up of 6mo, visual acuity, intraocular pressure ( lOP ), lOL position, and intraoperative and postoperative complications were observed.
●RESULTS: Visions of all the patients were improved at varying degrees. After follow-up of 6mo, no obvious lens deflected and serious complications ( glaucoma, retinal detachment) appeared.
●CONCLUSlON: Combined lensectomy with vitrectomy, retaining the peripheral anterior lens capsule for ocular trauma has good curative effects of lessening complications during operation and postoperation and good visual acuity recovery.
3.Inflammatory myofibroblastic tumors in dura mater of brain: one case report.
Hong ZENG ; Hai-gang LI ; Yun-jie ZENG
Chinese Journal of Pathology 2006;35(4):254-255
Actins
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metabolism
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Adult
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Brain Neoplasms
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metabolism
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pathology
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surgery
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Desmin
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metabolism
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Diagnosis, Differential
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Dura Mater
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chemistry
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pathology
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Female
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Granuloma, Plasma Cell
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metabolism
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pathology
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surgery
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Humans
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Immunohistochemistry
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Meningeal Neoplasms
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pathology
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Meningioma
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pathology
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Neoplasms, Muscle Tissue
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metabolism
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pathology
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surgery
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Vimentin
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metabolism
4.Hyponatremia induced by iodipamide: three cases report.
He HUANG ; Jian-ping ZENG ; Yun LONG
Chinese Journal of Cardiology 2009;37(7):621-621
5.Research progress of bladder cancer-related factors
Juanjuan ZHU ; Yun ZENG ; Baoxue YANG
Chinese Journal of Clinical Oncology 2013;(12):741-744
10.3969/j.issn.1000-8179.2013.12.015
6.Medical journal Yi Chao published in the period of Republic of China:Its contents and historical values
Yun ZHANG ; Yi ZENG ; Wenlin LI
Chinese Journal of Medical Library and Information Science 2014;(2):72-74
After the background, main contents and paper writers of the medical journal Yi Chao founded in Nanjing during the late period of Republic of China were analyzed with stress laid on its characteristics of nursing experiences and surgical treatment procedures for diseases, its historical values in studying the debate on traditional Chinese and Western medicine and the history of public health and medical cause during the period of Republic of China were elaborated.
7.Relationship between polymorphism of FcγRIIIA F158V genotype andsystemic lupus erythermatosus as well as lupus nephritis in Chinese Han population
Yun ZHANG ; Shufen LIU ; Xuejun ZENG
Basic & Clinical Medicine 2017;37(5):709-713
Objective To find the frequencies of FcγRIIIA polymorphisms in Chinese people and the potential role of these polymorphisms(SNPs) in systemic lupus erythermatosus(SLE) and lupus nephritis(LN).Methods The investigation covers 324 unrelated Chinese SLE patients and 319 controls.FcγRIIIA F158V polymorphism was genotyped by specific primer-polymerase chain reaction(PCR).Results The frequency of F allele of FcγRIIIA polymorphism is 60.8% in Chinese people.FcγRIIIA polymorphism revealed a significant difference of both genotype and allele distribution in SLE patients and controls.LN patients have a significant increase in carrier frequency of the FF genotype, while the VV genotype reveals a significant decreased risk of early onset of LN.ConclusionsFcγRIIIA polymorphisms is potentially related with SLE in Chinese people.The homozygous FF genotype of FcγRIIIA might be the risk factor for LN, while the homozygous VV genotype might be the protective factor for late onset lupus nephritis.
8.Application of failure mode and effect analysis on reducing the unplanned extubation rates for patients with severe craniocerebral injury
Yan JI ; Yun ZHEN ; Yunxiang ZENG
Chinese Journal of Practical Nursing 2017;33(6):450-453
Objective To explore the effect of failure mode and effect analysis (FMEA) on reducing the unplanned extubation rates for patients with severe craniocerebral injury. Methods FMEA model was used to analyze the main reasons of unplanned extubation patients with severe craniocerebral injury, 7 failure modes with higher RPN scores was selected. The nursing intervention for the fixation of the catheter were improved. The control group with 181 cases of patients without FMEA application were given routine care. FMEA group owning 196 cases were given the optimization process. The incidence rate of unplanned extubation of two groups was compared. Results After improvement of the nursing process of patients with severe craniocerebral injury for fixing the catheter, the RPN of 7 failure modes was lowered. Compared with the control group, the total rate of unplanned extubation in FMEA group decreased to 1.1% (9/832), less than 5.1% (40/779) of the control group. The statistical difference was significant (χ2=22.410, P < 0.01) . The rate of UEX in gastric tube, urinary catheter and central venous catheter were 3.1%(6/196), 1.0%(2/196), 0, lower than 8.8%(16/181), 4.9%(9/181), 3.9%(7/181) in the control group. The statistical difference was significant(χ2=5.718, 5.224, 7.724, P < 0.05). No statistical difference in tracheal cannula and drainage tube of head between the two groups was found(P>0.05). Conclusions The FMEA model can be effective in reducing the rate of unplanned extubation .
9.Treatment of acute retinal necrosis syndrome
International Eye Science 2015;(5):813-816
?Acute retinal necrosis syndrome ( ARN) is a serious eye disease, which caused by Herpes virus mostly, with unknown pathogenesis. Because of the aggressive progression, treatment of ARN is difficult, and the blindness rate is extremely high. Current treatment strategies are the combination of the drug therapy and the operative treatment. Drugs commonly used are antiviral drugs, glucocorticoids, and antiplatelet drugs, and the operative treatment includes laser photocoagulation and vitrectomy.
10.Inhibitory Effect of Chinese Herbal Compound Dongju on Tongue Carcinogenesis in Rats
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(10):-
Objective To examine the inhibitory effect of Chinese herbal Compound Dongju on 4-nitroquinoline 1-oxide(4NQO)-induced tongue carcinogenesis in rats. Methods A total of 85 Wistar rats were divided into four groups: model group(n=35),administration group(n=35),normal control group(n=5) and herb control group(n=10).4NQO dissolved in drinking water was administered orally to induce tongue carcinogenesis in rats.The herb compound was injected into the stomach of the rats during oral carcinogenesis.Rats were sacrificed at 9,13,20,24 and 32 weeks from the beginning of the experiment.The tongues of the rats were dissected for gross and histological assessment,and SP immunohistochemical method was also employed to detect the expression of cyclin D1 in the specimens. Results Compared with the model group,the incidence of dysplasia and the positive rate of cyclin D1 were suppressed by Compound Dongju(P