1.Detection of chromosomally abnormal fetuses by nuchal translucency
Chinese Journal of Ultrasonography 1993;0(01):-
Objective To assess the ultrasonographic detection of nuchal translucency or nuchal edema in identifying chromosomally abnormal fetuses.Methods Fetal nuchal translucency thickness was measured between 10~14 weeks of gestation,or nuchal fold thickness after 14 weeks,with serial follow-up ultrasound examinations.Results In a 2-year period,12 aneuploid fetuses had been identified,together with 5 fetuses of normal karyotype but fatal prognosis.Compared with the fetuses of increased nuchal translucency but normal karyotype and normal follow-up,they had a much thicker nuchal translucency in the first trimester (average 6.1 mm vs 3.6 mm),and in most cases the nuchal translucency evolved into nuchal edema in the second trimester,with other abnormalities detected by ultrasound.Conclusions Detection of increased nuchal translucency by ultrasound is effective in detecting chromosomally abnormal fetuses or fetuses with other abnomalities,and the changes of nuchal translucency observed by follow-up ultrasound may play an important role in differential diagnosis and predicting the prognosis.
2.Immunoprotection of gastric mucosa in newborn mice after oral immunization with inactived H.pylori
Chinese Journal of Immunology 2016;(2):201-204
Objective:To explore the Immunoprotection of gastric mucosa in newborn mice after oral immunization with inactived H.pylori.Methods:Thirty-two BALB/c mice were randomly divided into four groups, including PBS control group ( groupⅠ) ,the group of inactivated H.pylori ( groupⅡ) , the group of inactivated H.pylori and Escherichia cole heat-labile enterotoxin B subunit( LTB) ( groupⅢ) ,and normal group( groupⅣ).Newborn BLAB/c mice within 24 hours were immunized through oral gavage with corresponding antigen,Two weeks after final immunization,the mice were challenged with 1×108CFU live H.pylori strain SS1, twice once day,for 2 days.The twenty-eighth day post-challenge,all of mice were sacrificed and stomachs were removed for grades of in-flammation and The counting of H.pylori colonizing.Results:The mean scores of stomach tissue inflammation of groupⅠ,Ⅱ,Ⅲ andⅣwere 2.25±0.46,2.12±0.35,1.5±0.53,0.25±0.46,respectively,and the score of inflammatory activity of the above four groups were 2.12±0.35,2.12±0.35,1.37±0.52,0.25±0.46.Among these four groups,the results were statistically significant between any two groups except the result between groupⅠand groupⅡ.Finally,H.pylori colonization quantity in the stomachs of groupⅢwas lower than groupⅠand group Ⅱ( P<0.05 ) , as expected, the H.pylori colonization was undetectable in group Ⅳ.Conclusion: The oral gavage with inactived H.pylori plus LTB to newborn mice may be associate with the lightening of inflammation and the decrease of H.pylori colonizing number.
3.Pregnancy within a cesarean delivery scar with placenta accreta in first trimester: diagnosis and conservative management with ultrasonography
Chinese Journal of Ultrasonography 2003;0(11):-
0.6. Conclusions Ultrasonography plays an important role in the diagnosis and conservative therapy of pregnancy within a cesarean delivery scar with placenta increta.
5.Color Doppler ultrasonographic study of crural arterial diseases
Chinese Journal of Ultrasonography 2003;0(08):-
50%,0-patent lumen.Those legs with dominant crural arterial lesion (gradeⅠ,Ⅱor Ⅲ) on at least one segments and without femoropopliteal arterial obstructions were selected.Results Totally 75 legs were involved.There were 53 legs( 70.7%) with only 1 main artery damaged,14 legs( 18.7%) with 2 main arteries damaged,and 8 legs( 10.6%) with all 3 main arteries damaged.Among the 5 arterial segments,the anterior tibial arterial lesions were found most frequently ( 73.3%,55/75),in which the segmental occlusion (gradeⅡ) was the most common type.The peroneal arterial lesions appeared least ( 20.0%,15/75).In the damaged main arteries,1/3 anterior tibial-dorsal arteries and 1/5 posterior tibial arteries had greatly improved distal vascularity compared with their proximal and middle portion,owing to the collateral arteries around the ankle.Statistical analysis showed that there was close relationship between the blood flow damage of the distal portion of the posterior tibial arterial segments (medial trans-ankle flow) and the peroneal artery with the clinical ischemic manifestations.Conclusions The dominant occlusive crural arterial lesions and the collateral arteries can be well imaged and diagnosed by color Doppler ultrasonography,which is helpful in providing accurate information of the blood supply of the distal part of the lower extremity.
8.Analysis of professor ZHANG Lei's cleaning turbidity therapy
Feng JIANG ; Rongxin ZHANG ; Yuxin SUN
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(01):-
Professor ZHANG Lei is one of the most renowned doctors in traditional Chinese medicine. He is good at treating miscellaneous disease of internal medicine, and summarizes eight clinical therapy from long-term clinical practice, and cleaning turbidity therapy is one of the most characteristic therapy. Cleaning turbidity therapy is founded under today's improvement of living standards and changes of lifestyle where more and more turbidity syndromes are caused. Qianjin Weijing Decoction is used as main prescription and modified according to different zang-fu where turbidity syndromes are located. On account of cleaning turbidity therapy is one of the eliminating pathogens therapy, strengthening healthy qi must be used according to power of healthy qi, especially healthy qi of spleen and stomach.
9.Ultrasonography detection of parathyroid lesions in patients with hyperparathyroidism
He LIU ; Yuxin JIANG ; Jinxi ZHANG
Chinese Journal of Ultrasonography 2003;0(08):-
Objective To evaluate the usefulness of ultrasonography in detecting parathyroid lesions in the patients with hyperparathyroidism. Methods The results of ultrasonography were compared with operative and histologic findings, and other imaging techniques such as 99m-Tc-sestamibi scintigraphy and CT in 210 patients with proved hyperparathyroidism.Results The overall sensitivity and specificity of ultrasonography in detecting parathyroid lesions were 68.62%, 93.79%. Lesions at lower pole of thyroid were more likely to be detected than ectopic ones. Ultrasonography was helpful in diagnosis of parathyroid adenoma, hyperplasia or carcinoma when combined with clinical manifestations. Conclusions Ultrasonography is a useful means in preoperative localizing of hyperparathyroidism.
10.Color Doppler ultrasonography in the diagnosis of malignant mullerian mixed tumor
Meng YANG ; Yuxin JIANG ; Qing DAI
Chinese Journal of Ultrasonography 2010;19(3):241-244
Objective To investigate the correlation of ultrasonographic characteristics and pathologic features for malignant mullerian mixed tumor(MMMT)and determine the diagnostic value of ultrasonography.Methods The uItrasonographic features of 10 MMMTs were analyzed retrospectively and the sonographic findings were compared with histological results and discussed the correlation.Results The morphologic features of US and histology were well associated.Large,solitary lesion,ill-defined irregular shape,honeycombed heterogenous echo-pattern,scattered cystic areas and increased irregular peripheral/internal color flow were typical US findings.Logistic regression analysis showed the type of tumor liquefaction to be the most significant independent predictor of vascularity.Conclusions Ultrasonography is helpful for the diagnosis of MMMT,the uhrasonographic characteristics of MMMT are well correlated to its pathologic features.