1.NURSING EFFICACY OF ENDOVASCULAR -HYPOTHERMIA IN TREATMENT OF SEVERE BRAIN INJURY
Modern Hospital 2015;(4):99-101
Objective To observe the clinical efficacy of endovascular -hypothermia in treatment of severe brain injury.Methods 40 cases of severe brain injury were given the endovascular -hypothermia treatment and the basic treatment accordingly.The time to reach target temperature and the stability to maintain target temperature were observed.The patients'ICP at different points were recorded .The cases were estimated by Glasgow Coma Scale (GCS) before and after treatment and their complications during treatment were observed .Results The time to reach target temperature was (136 ±42)min and only (6.20 ±1.68)% of the measurement time deviated from target tempera -ture.ICP was reduced as the temperature fell and maintained in normal range after re -warming process.The ICP af-ter treatment was significant difference (p <0.05).The GCS was also significant higher after treatment than before (p <0.05).The complications of the patients were fewer and can be controlled after corresponding treatments .Conclu-sion In the endovascular -hypothermia treatment, the time to reach target temperature was short and the stability to maintain target temperature was strong.The endovascular -hypothermia treatment can reduce patients 'ICP and improve their awareness.There was no serious complication during treatment .This treatment can be safe and reliable.
2.Trematode Aspidogastrea found in Huaihe River
Chinese Journal of Schistosomiasis Control 2015;(1):62-63
Objective To investigate the epidemic situation of trematode Aspidogastrea in the Huaihe River. Methods The mussels in the Huaihe River were collected numbered and dissected to detect the trematode and the species of trematodes were identified after dyeing. Results Totally 79 mussels were collected and the trematode Aspidogastrea were found from 23 mussels with the infection rate of 29.11% 209 trematode Aspidogastrea were collected and the average infectiosity of mussels was 9.09. Conclusion Trematode Aspidogastrea is endemic in the Huaihe River and the species is Aspidogaster sp.
3.Efficacy of domestic rhG-CSF on leucopenia induced by chemotherapy in patients with gynecological tumors
Chinese Journal of Clinical Pharmacology and Therapeutics 2004;0(11):-
0.05). But in repeated chemotherapy, the period of leukopenia recovered to normal was shorter in group B than that in group A or group C. The effects of the domestic rhG-CSF on leu-copenia induced by chemotherapy were similar to the imported products of same dose. CONCLUSION: Low dose of domestic rhG-CSF (75?g) can effectively treat the leukopenia caused by postchemotherapy in patients with gynecological tumors. 150?g of domestic rhG-CSF is more effective than 75?g of domestic or import rhG-CSF in treating leukopenia in repeated chemotherapy.
4.Exploration into the molding of humanistic spirit in high medical education
Chinese Medical Ethics 1994;0(05):-
The molding of humanistic spirit in medical colleges and universities has a direct bearing on whether or not the cultivated medical students can establish fundamentally the mental idea of humanistic solicitude and orientation of value.This article expounds the importance and urgency of strengthening the molding of humanistic spirit in medical colleges and universities,and analyzes the current situations of construction of humanistic spirit in colleges and universities of our country at present,and investigates the ways and countermeasures of strengthening the molding of humanistic spirit in medical colleges and universities.
5.CT perfusion imaging in patients with transient ischemic attack: a prospective case series study
Yuxia LI ; Yongqiu LI ; Suzhi LIU
International Journal of Cerebrovascular Diseases 2013;21(12):881-885
Objective To investigate the changes of CT perfusion (CTP) imaging and the risk factors for CTP abnormality in patients with transient ischemic attack (TIA).Methods TIA patients were enrolled; CTP and CT angiography were performed.The parameter values of cerebral blood flow (CBF),cerebral blood volume (CBV),mean transit time (MTT),and time to peak (TTP) were obtained.CTP abnormalities were identified by comparing the contralateral mirror area.Demography and baseline clinical data were compared in a CTP imaging abnormal group and a normal group.Multivariate logistic regression analysis was used to identify the risk factors for CTP abnormality in patients with TIA.Results A total of 69 patients with TIA were enrolled,and 52 of them had perfusion abnormalities corresponding to clinical symptoms.Their TTP and MTT were prolonged,but the decreased CBF and CBV was not obvious.Multivariate logistic regression analysis showed that the higher National Institutes of Health Stroke Scale (NIHSS) score (odds ratio [OR] 1.991,95% confidence interval [OR] 1.113-3.564; P=0.020),the longer duration of symptoms (OR 1.062,95% OR 1.013-1.114; P =0.013),and intracranial vascular stenosis (OR 15.410,95% OR 2.118-112.116; P=0.007) were the independent risk factors for CTP abnormality in patients with TIA.The correlation analysis showed that the prolonged TTP (r =0.389,P =0.001) and MTT (r =0.413,P=0.001) were significantly associated with the NIHSS score.Conclusions TTP and MTT may sensitivity reveal cerebral perfusion abnormalities in patients with TIA.The more severe the disease is,the higher the CTP abnormal rate will be.
6.Acarophenax tribalii found in stored grains
Ning TAO ; Yuxia ZHU ; Chaopin LI
Chinese Journal of Schistosomiasis Control 2016;28(5):584-585
Objective To observe and understand the morphology and structure of Acarophenax tribalii in order to create a new record of this mite in China. Methods The stored grain samples(rice and brown rice)were collected from the storage of lo?cal dwellers,and mites breeding in the products were isolated. Then mite samples were prepared and identified as the previous protocols,and the species was classified in accordance with Hughes. Results A. tribalii was detected in the grain samples. The light microscopic examination exhibited ovally shaped idiosoma of this species,and the abdomen of the male was more inflated than that of the female. By general view,the propodosomatal plate appeared triangle?like,and its anterior margin was covered by the gnathosoma. Leg I consisted of four segments,and its tibia and tarsus healing were fused into a stubby tibiotarsus. A tarsulus occurred at the end of legⅡ,ⅢandⅣ,with a claw born at each leg. Conclusion The morphology and structure of A. tribalii are characterized. This may lay a basis for following study on this species.
7.Effect of retinoic acid on the secretion of C3 and factor B in lung carcinoma cell line A549 induced by TNF-? and IL-6
Yuxia ZHAO ; Guang LI ; Runjiang YU
Chinese Journal of Immunology 1985;0(06):-
Objective:To study the effect of retinoic acid(RA) which is used in malignant tumor therapy on the secretion of C3 and factor B in human lung cancer cell line A549 induced by TNF-? and IL-6.Methods:C3 and factor B in the culture medium were measured by ELISA and Western blot,the mRNA expression of C3 and factor B was analyzed by RT-PCR.Results:When using TNF-?(10 ?g/L),IL-6(50 ?g/L) and RA(1 ?mol/L),the results of ELISA,Western blot and RT-PCR showed that TNF-? and IL-6 promoted A549 cells excreting C3 and factor B and their mRNA expression;RA alone did not affect C3 and factor B;in TNF-? group and TNF-?+RA group,the amounts of C3 were 91.40?12.59 and 133.59?11.25(ng/10~6 cells) respectively(P0.05),and the amounts of factor B were 13.07?2.50 and 32.89?4.22(ng/10~6 cells) respectively(P
8.Application of psychological intervention and rehabilitation training in patients with cerebral hemorrhage during postoperative recovery stage
Yan YUAN ; Decui LI ; Yuxia WANG
Chinese Journal of Practical Nursing 2012;28(12):1-3
ObjectiveTo investigate the effect of psychological intervention and rehabilitation training on self-care ability and quality of life in patients with cerebral hemorrhage during postoperative recovery stage. Methods180 patients with cerebral hemorrhage in our hospital from October 2008 to December 2010 were randomly divided into the observation group and the control group with 90 cases in each group.The control group was given with routine care and rehabilitation measures.The observation group adopted psychological intervention and rehabilitation training based on the routine care.After treatment,the functional independence measure (FIM)and the quality of life index (QLI)were used for the evaluation of the level of quality of life and self-care ability. ResultsIn the quality of life index,the QLI score after treatment in the observation group improved significantly compared with that before treat ment.The QLI score in the control group before and after treatment showed no statistical difference.In the self-care ability,FIM score after treatment in both of the two groups improved significantly than that before.And FIM score after treatment in the observation group was significantly higher than that of the control group. ConclusionsApplication of psychological intervention and rebabilitation training in patients with cerebral hemorrhage during postoperative recovery stage shows pivotal importance.It can improve self-care ability and quality of life of patients and promote recovery effectively.
9.Innovation of teaching supervision in higher medical institutions
Yuxia SUN ; Yihan WEI ; Xiaoxia LI
Chinese Journal of Medical Education Research 2013;(4):388-391
Constructing internal quality control system is an important measure to improve teaching quality in the universities.Teaching supervision plays an important role in the teaching quality guaranteeing system.This article introduced and summarized the practice of teaching supervision in Tianjin Medical University including the establishment of three-leveled teaching supervision,emphasis of process management,innovation,significance and achievements of teaching supervision.
10.Efficacy of flexible laryngeal mask airway and sevoflurane in pediatric strabismus surgery
Lihua TANG ; Yuxia JIAO ; Dongbai LI
Chinese Journal of Postgraduates of Medicine 2011;34(18):11-14
Objective To evaluate the efficacy of flexible laryngeal mask airway and sevoflurane in pediatric strabismus surgery. Methods Totally 60 children undergoing elective strabismus surgery were recruited and divided into two groups with 30 cases each by random digits table:group T, in which children accepted endotracheal tube intubation and combined intravenous and inhalation anesthesia with mechanically ventilation; and group F, in which children adopted both flexible laryngeal mask airway and inhalation anesthesia of sevoflurane with spontaneous breath. Airway peak pressure (Ppeak), average airway pressure (Pmean), blood pressure (Bp) and heart rate (HR) at induction (T1), 1 min (T2), 3 min (T3) and 5 min (T4) after induction, removal of endotracheal tube or laryngeal mask airway (T5), awaking time and extubation time, occurrence of cough, dysphoria and pharyngodynia from being awake to extubation, satisfaction of patients were recorded. Results When compared to baseline, systolic pressure was lower at T, and higher at T2, T3 and T5, and HR was higher at T2-T5 in group T(P< 0.05),Bp was lower at T1-T4 in group F (P < 0.05). Bp and HR at T2-T5 in group F were lower than those in group T (P < 0.05). The awaking time was (8.1 ?2.6) min, the extubation time was (12.6 ?3.2) min, the occurrence of cough and pharyngodynia was 66.7%(20/30), 40.0%( 12/30), the dysphoria (0-1 score) was 7 cases in group T,(5.2 ± 1.1) min, (6.3 ± 1.5) rain,0,6.7%(2/30),25 cases in group F. There were significant differences between two groups (P<0.05). The satisfaction of patients in group F was higher than that in group T, there was significant difference between two groups (P< 0.05). Conclusion Flexible laryngeal mask airway with sevoflurane could offer high efficacy in pediatric strabismus surgery.