To sum up the experience in diagnosis and differential diagnosis in complicated cyanotic congenital heart defects, the clinical symptoms,physical signs, electrocardiogram, echocardiography and angiocardiography were analysed retrospectively in 2 366 patients with six kinds of common cardiac deformities. The results suggest that: ①It is helpful in diagnosis to grasp unusual symptoms and physical signs; ②Specific electrocardiographic features and X ray findings are valuable in diagnosis and differential diagnosis; ③ Echocardiography is significant in the diagnosis, but it can not show the branches of pulmonary arteries.Its diagnostic rate is 97 2%; ④Angiocardiography can clearly display the pulmonary arteries, and it is valuable for surgical operation, its diagnostic rate is 98 1%.

patients with infective endocarditis were analyzed. Anong them, 75 were patients with congenital heart disease (72 1%), 21 were patients with rheumatic heart disease and 8 were patients without heart disease(7 7%). It is suggested that early diagnoses and treatment of CHD are the main pretective methods for reducing the incidence of IE; the incidence of fever, anaemia, embolism, hepatomegaly and splenomegaly, etc. declines notably; the possibility of excrescence invading aortic valve (44 2%) is higher than that of mitral valve (24 7%), and IE of aortic valve results in heart failure in a short while and the valve replacement should be done as early as possible; positive rate of blood culture declines because of extensive use of antibiotics; appropriate medical treatment combined with active surgical treatment plays an important role in the treatment of IE.

Objective To observe the changes in protein expression of NMDA receptor subunit NR1 in rat hippocampal subfields following transient forebrain ischemia. Methods immunohistochemistry and computer-assisted image analysis techniques were used. Results Early stage after reperfusion,NR1 protein expression levels were lower than that of sham control in all hippocampal subfields(P