Ventricular arrhythmias closely correlates with stress.Not only individuals with organic heart diseases have a high risk of ventricular arrhythmias,healthy individuals are also susceptible to ventricular arrhythmias during stress.Electrophysiological characteristics of myocardium changes apparently during stress and electrical unstability of myocardium increases,which makes reentry and early afterdepolarization easy to happen.

There are many factors which can affect the genesis and prognosis of the stress-induced arrhythmias,besides the automatic nerve system,the personality,central nervous system and hereditary factors have been involved.It is very important to comprehend the relationship and effects of these factors for prevention of stress-induced arrhythmias.

cases of plasma cell mastitis were treated from 1986 to 1999,of whom 37(32.5%) suffered from subareolar abcess and sclerosis,77(67 5%)had subareolar fistula.There were 58 cases(50 8%)of crater nipple.We adopted an arc incision along the edge of areolamammae to remove the necrotic tissues of the ducts,followed by everting suture and mamilliplasty.104 cases(91 2%)achieved healing by first intention.The operations were well done with little injury.Moreover,patients would be satisfied with the appearance.

Objective To investigate the effects of L-carnitine(L-CN)on electrophysiological changes induced by atrial ischemia in dogs.Methods Twelve dogs were divided into normal saline(NS)group and L-CN group.Atrial ischemia was induced by ligation of an atrial arterial branch of right coronary artery.Atrial effective refractory period(AERP)and conduction velocity(CV)of right atrium were measured before and after 3 hour's coronary artery ligation.Atrial wavelength(WL)and inducibility of atrial fibrillation(AF)were calculated.Histological examination was performed.Results (1)AERP and WL shortened dramatically after ligation of coronary artery in NS group;they showed no remarkable change in L-CN group.(2)There was no significant change of CV in the two groups.(3)AF was induced in 0 of 12 dogs under basic condition.(3)After ligation of the right coronary artery,AF was induced in all of the 6 dogs in NS group and 0 of 6 dogs in L-CN group.(5)Histological examination revealed that the ischemic changes occurred only in NS group.Conclusion Electrophysiological changes induced by atrial ischemia could be prevented by infusion of L-CN.

Objectives To evaluate the safety of intravenous amiodarone in patients with atrial fibrillation and rapid ventricular response via an accessory pathway. Methods Sixteen patients with Wolff Parkinson White syndrome (W P W group) and 16 patients with concealed accessory pathway (control group) were included. The anterograde effective refractory period of accessory pathway (ERP AP ) in W P W group and the effective refractory period of atrioventricular node (ERP AVN ) in control group were measured. Then 150mg of amiodarone was injected intravenously in 10min, the ERP AP and ERP AVN were remeasured 10min later. Results After amiodarone injection, ERP AP was increased slightly ( P

Chromosome Deletion ; Chromosomes, Human, Pair 9 ; Craniofacial Abnormalities ; diagnosis ; Heart Defects, Congenital ; diagnosis ; Humans ; Intellectual Disability ; diagnosis

AIM: To determine the effect of exogenous phosphocreatine (PCr) at different concentrations on transient outward potassium (Ito) current in rat ischemic ventricular mid-myocardial (M) cells and to explore the antiarrhythmia mechanism in the treatment of ischemic heart disease. METHODS: M cells were isolated enzymatically from left ventricular mid-myocardium of rats. Peak Ito current was recorded by patch-clamp technique in the whole-cell configuration when M cells were superfused with normal Tyrode solution,simple ischemic solution,and simulated ischemic solution containing PCr at concentrations of 5,10,20 and 30 mmol/L for 10 min. RESULTS: Peak Ito current density of M cells superfused with simple simulated ischemic solution was significantly reduced by (76.1±6.3)% (P<0.05) compared with M cells superfused with Tyrode solution. Ischemic solution containing 5,10,20 and 30 mmol/L PCr reduced peak Ito current density by (57.1±9.6)% (P<0.05),(40.3±10.3)% (P<0.05),(34.3±9.6)% (P<0.05) and (32.1±10.6)% (P<0.05),respectively. There was statistical difference among ischemic solution without PCr and containing PCr at concentrations of 5 and 10 mmol/L groups (P<0.05). No statistical difference among groups of 10,20 and 30 mmol/L PCr was observed (P>0.05). CONCLUSION: PCr reverses the inhibition of Ito current under ischemic condition in M cells,which may be the mechanism responsible for arrhythmia prevention in ischemic heart disease. PCr at concentrations of 0～10 mmol/L exerts significant dose-effect relationship.

Objective To study the characteristics and regularities of somatotype growth of Yugu adolescents.Methods The somato-type growth of 989 Yugu adolescents(male:512,female:477)in Sunan was evaluated by the Heath-Carter method.Results The average somatotype of YuGu adolescents in males was mesomorphic ectomorph(3.0-3.6-3.7),and in females,the average somatotype was ectomorphic endomorph(3.8-2.9-3.6).The somatotypes develop from central,endomorphic ectomorph to mesomorphic ectomorph in the male,however,in the female from central,ectomorphic endomorph,endomorphic ectomorph,to mesomorphic endomorph.Conclusion The somatotypes of Yugu adolescents are very different between males and females.In the male group,the somatotypes of the 7-12 year-old group of Yugu adolescents are similar to the Mongolia,Han ethnic,Zhuang ethnic and Hungary.The somatotypes of 13-17 year-old group are similar to Tibetan,Zhuang ethnic,Han ethnic and Daur.However for the female group,the somatotypes of the 7-9 year-old group are similar to Hungary,and the 10-17 year-old group are similar to Tibetan,Zhuang ethnic,Han ethnic and Finn.

AIM: To make a comparison between 64-multidetector computed tomography (64-MDCT) and coronary angiography (CAG) for assessing the clinical significance of coronary lesions and the coincidence rate of these two methods. METHODS: From May 2005 to July 2006, totally 85 patients, who were suspected or diagnosed as coronary atherosclerotic heart disease, were performed with both 64-MDCT and CAG in the General Hospital of Chinese PLA. They included 64 males and 21 females, aged 41-83 years, with a mean of 61 years. Informed consents were obtained from all the patients. Coronary artery stenosis was detected with the stenosis rate of diameter method and area method, which was calculated by 64-MDCT and analysis software for vessels. Coronary luminal diameter was evaluated as normal, mild stenosis (25%-49%), mild-moderate stenosis (50%-74%), moderate-severe stenosis (75%-94%), severe stenosis (95%-99%), and occlusion (100%). RESULTS: The 64-MDCT images were evaluated for the existence of occlusions or significant stenosis (≥50% lumen reduction) in native coronary arteries. Its coincidence rate with CAG was 89% in left coronary artery main stem, 93% in left anterior descending coronary artery, 68% in left circumflex coronary artery, and 48% in right coronary artery. CONCLUSION: The 64-MDCT has a high diagnostic accuracy in detecting coronary artery stenosis, and is identical with CAG in the assessment of left coronary artery main stem and left anterior descending coronary artery. Thus it is potential for the clinical application on the evaluation of coronary artery stenosis, qualitative and quantitative detection of coronary atherosclerotic plaque.